Ecotoxicology and Environmental Safety, 2023 Ticlopidine exerts its anti-platelet effects mainly by antagonizing platelet p2y12 receptors. Previously, a few studies have shown that ticlopidine can induce liver injury, but the exact mechanism of hepatotoxicity remains unclear.
海燕 魏, Huiqiang Lu
exaly +3 more sources
THE EFFECTIVENESS OF CLOPIDOGREL AS AN ANTITHROMBOTIC COMPARED TO TICLOPIDINE AND ASPIRIN (META-ANALYSIS) [PDF]
Jurnal Farmasi Sains dan Komunitas, 2017 Clopidogrel, an antithrombotic drug, has been proven by FDA as Plavix® was initially used for the prevention of vascular occlusive that cause of myocardial infarction, stroke, and vascular death in patients with atherosclerosis and then it is used to ...
Titien Siwi Hartayu, Dewi Setyaningsih
doaj +6 more sources
Overcoming Clopidogrel Resistance in Carotid Artery Stenting: Experience with Ticagrelor and Ticlopidine [PDF]
Clinics and PracticeObjectives: The goal of this study is to establish the incidence of high on-treatment platelet reactivity (HTPR) to aspirin and clopidogrel in patients undergoing carotid stenting and to evaluate the efficacy of ticagrelor and ticlopidine in patients ...
Pavol Vigláš +6 more
doaj +2 more sources
When Delirium Unmasks a Silent Myocardial Infarction [PDF]
Journal of the American Geriatrics Society, Volume 74, Issue 2, Page 623-625, February 2026.Abbreviations: hs‐TnT: high sensitivity Troponin T; STEMI: ST‐elevation myocardial infarction.
Eugenia Casali +10 more
wiley +2 more sources
Aortic thrombus in a patient with myeloproliferative thrombocytosis, successfully treated by pharmaceutical therapy: a case report [PDF]
Journal of Medical Case Reports, 2010 Introduction Thrombosis in myeloproliferative thrombocytosis occurs usually in the microvessels and medium-sized arteries and veins and only rarely in the aorta. Aortic thrombosis is usually treated with thrombectomy.
Imai Norikazu +4 more
doaj +4 more sources
A Critical Review of the Molecular and Clinical Effects of Cilostazol After Percutaneous Coronary Intervention [PDF]
Journal of Cardiovascular Development and DiseaseBackground: Restenosis after coronary stent implantation remains a major clinical challenge, especially in patients with diabetes, long lesions, or multiple stents.
Roberto Ferrari +1 more
doaj +2 more sources
Potent Antisickling Furaldehyde Analogs for Acute Sickle Cell Therapy: Enhanced Efficacy and Intravenous Formulation Potential [PDF]
ChemMedChem, Volume 20, Issue 22, November 18, 2025.This study reports novel 5‐HMF analogs with potent antisickling activities. Lead compound MMA509 enhances hemoglobin oxygen affinity and prevents erythrocyte sickling. Crystal structure of hemoglobin‐MMA509 complex explains MMA509 mechanism of action. An IV formulation is successfully developed, positioning MMA509 as a promising fast‐acting treatment ...
Abdelsattar M. Omar +15 more
wiley +2 more sources
Ecotoxicology and Environmental Safety, 2022 Ticlopidine has inhibitory effects on platelet aggregation via ADP (adenosine diphosphate), platelet release reaction and depolymerization. In clinical practice, it is commonly used to prevent heart, cerebrovascular and other thromboembolic diseases ...
Rong Xu +9 more
doaj +1 more source
AASLD practice guidance on drug, herbal, and dietary supplement–induced liver injury
, 2022 Hepatology, EarlyView.
Robert J. Fontana +6 more
wiley +1 more source
Neuroborreliosis in patient with aplastic anaemia secondary to therapy with ticlopidine [PDF]
Srpski Arhiv za Celokupno Lekarstvo, 2010 Introduction. Aplastic anaemia is a rare but potentially fatal complication of treatment with ticlopidine. Case Outline. We present a 55-year-old male with aplastic anaemia which developed after 45 days of the therapy with 200 mg ticlopidine to ...
Čolović Milica +4 more
doaj +1 more source