Results 61 to 70 of about 12,121 (179)

Cilostazol reduces restenosis after carotid artery stenting [PDF]

, 2010
BACKGROUND: Although carotid artery stenting (CAS) has been proposed as an alternative to carotid endarterectomy in cerebral revascularization, restenosis remains an unsolved issue.
Hayakawa Mikito, Matsumaru Yuji, Matsumura Akira, Nemoto Shigeru, Takigawa Tomoji, 松村 明, 滝川 知司   +6 more
core   +1 more source

CYP2C19 genotype testing for clopidogrel: A guideline developed by the UK Centre of Excellence in Regulatory Science and Innovation in Pharmacogenomics (CERSI‐PGx)

British Journal of Clinical Pharmacology, Volume 92, Issue 2, Page 329-347, February 2026.
Clopidogrel, an antiplatelet agent, is currently licensed in the United Kingdom for the prevention and treatment of atherothrombotic events in cerebrovascular disease, coronary artery disease and peripheral arterial disease. Clopidogrel requires metabolic activation by the cytochrome P450 enzyme CYP2C19 to be effective.
Cinzia Dello Russo, Iain Frater, Rebecca Kuruvilla, Stefanie Lip, Hannah O'Neill, Kerry Burke, Vicky Chaplin, Alexander S. F. Doney, Salim Elyas, Nicholas Greaves, Sophie Harding, David Hargroves, Judith Hayward, Dyfrig A. Hughes, Tom A. T. Hughes, Sree Kondapally, Patrick Mok, Aaron Peace, Imran Rafi, Simon Ray, Vicky Stinton, Luigi Venetucci, Munir Pirmohamed   +22 more
wiley   +1 more source

Drugs for preventing red blood cell dehydration in people with sickle cell disease. [PDF]

, 2018
BACKGROUND: Sickle cell disease is an inherited disorder of hemoglobin, resulting in abnormal red blood cells. These are rigid and may block blood vessels leading to acute painful crises and other complications.
Ballas, Samir K., Nagalla, Srikanth
core   +1 more source

A Review on Ginkgo biloba: Nutritional Profile, Toxicity, and Its Therapeutic Potential in Stroke Management

eFood, Volume 7, Issue 1, February 2026.
Stroke is a neurological impairment caused by vascular injury of the central nervous system, and globally, stroke is ranked as the second most common cause of death and disability. Numerous risk factors, disease processes, and mechanisms can contribute to stroke, which is not a single disease. G.
Ali Ikram, Farhang Hameed Awlqadr, Hamna Tayyab, Mamoona Shehzadi, Muhammad Tayyab Arshad, Md. Sakhawot Hossain, Ahmadullah Zahir   +6 more
wiley   +1 more source

Antiplatelet combinations for prevention of atherothrombotic events

Vascular Health and Risk Management, 2011
Mario Bollat,i Fiorenzo Gaita, Matteo AnselminoDepartment of Internal Medicine, Division of Cardiology, University of Torino, ItalyAbstract: Antiplatelet therapy plays a fundamental role in reducing atherothrombotic events by several pathways.
Anselmino M, Bollati M, Gaita F
doaj  

Fibroelastoma of the mitral valve as a cause of transient ischemic stroke

Arquivos Brasileiros de Cardiologia, 2001
A 44-year-old woman had a transient ischemic stroke, fibroelastoma of the mitral valve being the source of the embolus. The patient evolved with neutropenia induced by ticlopidine after 10 days of treatment.
Alexandre Alessi, Roberto Gomes de Carvalho, Dalton Bertolin Précoma, Débora Fontoura, Luciano Rodrigo Oliveira, José Zanis Neto, Marcello Zapparoli   +6 more
doaj   +1 more source

Nonsteroidal Anti‐Inflammatory Drugs and Risk of Gastrointestinal Bleeding: A Systematic Review and Meta‐Analysis

Clinical Pharmacology &Therapeutics, Volume 119, Issue 1, Page 46-62, January 2026.
Nonsteroidal anti‐inflammatory drugs (NSAIDs) are widely used for pain and inflammation but are associated with gastrointestinal (GI) bleeding. While this risk is well established, most studies evaluate NSAIDs as a homogenous class, limiting clinical decision‐making based on individual agent safety.
Abdelrahman G. Tawfik, Ainhoa Gomez‐Lumbreras, Guilherme Del Fiol, Kensaku Kawamoto, Katy E. Trinkley, Thomas Reese, Aubrey Jones, Daniel C. Malone   +7 more
wiley   +1 more source

AGRANULOCYTOSIS AND MACULOPAPULAR RASH AFTER TREATMENT WITH TICLOPIDINE – CASE REPORT

Zdravniški Vestnik, 2003
Background. Ticlopidine is one of inhibitors of platelet aggregation indicated for reducing the risk of thrombotic stroke in patients who have experienced thrombotic stroke, ischemic attacks, unstable angina pectoris, coronary artery stenting and ...
Janja Blatnik, Gorazd Lešničar, Branko Šibanc, Stella Cvitan, Harry Strokol   +4 more
doaj  

Factors affecting adherence to guidelines for antithrombotic therapy in elderly patients with atrial fibrillation admitted to internal medicine wards [PDF]

, 2010
Current guidelines for ischemic stroke prevention in atrial fibrillation or flutter (AFF) recommend Vitamin K antagonists (VKAs) for patients at high-intermediate risk and aspirin for those at intermediate-low risk.
Altomare, E, Anastasio, L, Barreca, A, Bertolini, D, Bertolino, G, Bertucci, L, Bonelli, A, Cagnoni, C, Casella, G, Castoldi, L, Cavallo, P, Cazzaniga, M, Centenaro, GR, Colombo, S, Coralli, A, CORRAO, Salvatore, Cortellaro, M, Cuccuru, LM, Cuccurullo, O, Deidda, S, Dentamaro, G, Di Sciacca, R, Durante Mangoni, E, Fabio, G, Famularo, G, Fava, R, Ferrari, B, Fiorentini, A, Gaudenzi, P, Giannico, I, Giordano, A, Giusto, L, Gobbo, G, Gualandi, S, Hila, D, Incasa, E, Iorio, A, Liberato, NL, Longhini, C, Macura, A, Magagnotti, G, Mammarella, A, Mannucci, PM, Manucra, A, Marcucci, M, Marengoni, A, Mari, D, Matino, D, Meroni, MR, Micale, G, Molino, C, Monzani, V, Morabito, C, Moreo, G, Musca, G, Nobili, A, Pasina, L, Pasqui, AL, Perciccante, A, Picardi, A, Pinto, D, Puccetti, L, Quagliolo, M, Quercioli, A, Raparelli, V, Rasciti, L, Rizzoli, E, Rizzoni, D, Romanelli, G, Rondinella, S, Rossi, DP, Rossio, R, Rozzini, R, Sajeva, MR, Salerno, F, Savojardo, V, Semplicini, A, Serviddio, G, Tedeschi, A, Tettamanti, M, Tofi, C, TUTTOLOMONDO, Antonino, Vanoli, M, Vergani, C.   +83 more
core   +1 more source

Comparison of the Effects of Omeprazole and Rabeprazole on Ticlopidine Metabolism In Vitro

Journal of Pharmacological Sciences, 2011
.: The thienopyridine derivative ticlopidine (TCL) is an inhibitor of adenosine diphosphate-induced platelet aggregation. Combination therapy with a thienopyridine derivative and aspirin is standard after coronary stenting, although more hemorrhagic ...
Yuichi Kinoshita, Naoki Matsumoto, Minoru Watanabe, Yuko Takeba, Yutoku Yoshida, Keiichiro Ohba, Satoshi Suzuki, Fumio Itoh, Toshio Kumai, Shinichi Kobayashi   +9 more
doaj   +1 more source