Results 41 to 50 of about 156,135 (207)

Upper gastrointestinal lesions in patients receiving clopidogrel anti-platelet therapy

Journal of the Formosan Medical Association, 2012
Clopidogrel is associated with a high incidence of upper gastrointestinal bleeding in high-risk patients. However, the characteristic upper gastrointestinal lesions in symptomatic clopidogrel users remain unclear.
Tzung-Jiun Tsai, Kwok-Hung Lai, Ping-I. Hsu, Chiun-Ku Lin, Hoi-Hung Chan, Hsien-Chung Yu, Huay-Min Wang, Kung-Hung Lin, Kai-Ming Wang, Shiuh-Nan Chang, Chun-Peng Liu, Shin-Hung Hsiao, Hung-Ru Huang, Ching-Huang Lin, Feng-Woei Tsay   +14 more
doaj   +1 more source

Ticagrelor versus Clopidogrel in CYP2C19 Loss-of-Function Carriers with Stroke or TIA [PDF]

, 2021
BACKGROUND Comparisons between ticagrelor and clopidogrel for the secondary prevention of stroke in CYP2C19 loss-of-function carriers have not been extensively performed.
Li, Hao, Li, Wei, Liu, Liping, Lin, Jinxi, CHANCE-2 Investigators, Jing, Jing, Zhao, Xingquan, Li, Zixiao, Feng, Yefang, Xie, Xuewei, Wang, Lihua, Zhuang, Xiabo, Niu, Siying, Johnston, S. Claiborne, Dong, Qiang, Bath, Philip M., Wang, Baojun, Wang, Yilong, Jiang, Yong, Xu, Jie, Chang, Liguo, Meng, Xia, Pan, Yuesong, Xu, Anding, Wang, Anxin, Zhao, Jinguo, Li, Guozhong, Wang, Yongjun, Man, Honghao   +28 more
core   +1 more source

New therapeutic options for metabolic‐associated steatotic liver disease

British Journal of Clinical Pharmacology, EarlyView.
An increasing number of patients are being diagnosed with metabolic dysfunction‐associated steatotic liver disease (MASLD). MASLD results from disturbances in hepatic lipid metabolism and is associated with an increased risk of cirrhosis and hepatocellular carcinoma and significant extrahepatic morbidity, including cardiovascular disease and ...
Tessa Straatmijer, Midas Mulder
wiley   +1 more source

Cost-effectiveness of Platelet Function-Guided Strategy with Clopidogrel or Ticagrelor [PDF]

, 2019
Some patients treated with dual antiplatelet therapy (DAPT) following acute coronary syndrome (ACS) can still exhibit heightened residual platelet reactivity (HRPR), which is potentially linked to adverse vascular outcomes.
Liudmila Buryachkovskaya, Nikita Lomakin, Victor Serebruany, Anna Rudakova   +3 more
core   +1 more source

Clinical relevance of pharmacogenomic information for improving prescribing practices in acutely admitted older medical patients

British Journal of Clinical Pharmacology, EarlyView.
Aims Safe prescribing and effective medication review during acute hospitalization depends on accurate information about liver and kidney function because these organs are responsible for the elimination of most medications. While estimates for kidney function are widely used, comparable markers of hepatic drug‐metabolizing capacity are not routinely ...
Louise Westberg Strejby Christensen, Anne Kirstine Boas, Emilie Clausen, Nicoline Elers Koch, Anne Byriel Walls, Lotte Stig Nørgaard, Michael Asger Andersen, Anissa Aharaz, Rikke Lundsgaard Nielsen, Olivia Bornæs, Juliette Tavenier, Baker Nawfal Jawad, Helle Gybel Juul‐Larsen, Esben Iversen, Ove Andersen, Lona Louring Christrup, Kim Peder Dalhoff, Morten Baltzer Houlind   +17 more
wiley   +1 more source

The impact of pharmacogenetic‐informed care on medication adherence and psychological factors associated with adherence: A narrative review

British Journal of Clinical Pharmacology, EarlyView.
Improvement in medication adherence is often proposed as a potential advantage of pharmacogenetic‐guided prescribing over a traditional one‐size‐fits‐all approach. This paper provides a review of the published literature and presents the findings of studies that measure adherence to medication as an outcome of pharmacogenetic‐informed care, or that ...
Lucy Galloway, Alison Wright, John Weinman   +2 more
wiley   +1 more source

Periodontitis and atherosclerotic cardiovascular disease: A critical appraisal

Periodontology 2000, EarlyView., 2023
Abstract In spite of intensive research efforts driving spectacular advances in terms of prevention and treatments, cardiovascular diseases (CVDs) remain a leading health burden, accounting for 32% of all deaths (World Health Organization. “Cardiovascular Diseases (CVDs).” WHO, February 1, 2017, https://www.who.int/news‐room/fact‐sheets/detail ...
Maria Clotilde Carra, Hélène Rangé, Giuseppina Caligiuri, Philippe Bouchard   +3 more
wiley   +1 more source

Evaluation of clopidogrel response with light transmission aggregometry before extra- intracranial stenting

Ендоваскулярна нейрорентгенохірургія, 2020
Objective – to study the result of light transmission aggregometry with ADP for platelet reactivity before and after clopidogrel administration before extra-intracranial stenting. Materials and methods.
D.V. Shchehlov, M.B. Vyval, V.P. Khlopenova, S.M. Konobas   +3 more
doaj   +1 more source

Impact of clopidogrel in coronary artery bypass grafting [PDF]

, 2004
Objective: Clopidogrel has become the standard of care to prevent thrombotic complications following cardiological interventions, in particular intracoronary stenting.
Englberger, Lars, Carrel, Thierry, Faeh, Bettina, Eberli, Franz, Meier, Bernhard, Berdat, Pascal A.   +5 more
core   +2 more sources

Use of Intracoronary Pressure Wire Assessment and Association With Outcomes: Insights From the British Cardiovascular Intervention Society National Database

Catheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Background Despite recommendations in international guidelines, Intracoronary pressure wire assessment (PWA) utilization remains limited in clinical practice. This study aims to describe (i) trends of PWA during Percutaneous coronary interventional (PCI), (ii) factors that predict its application, and (iii) association with in‐hospital ...
Hussein Bashar, Muhammad Rashid, Mamas A. Mamas, Nick Curzen   +3 more
wiley   +1 more source