Results 21 to 30 of about 148,561 (252)

Safety of intravenous thrombolysis for acute ischemic stroke in patients receiving antiplatelet therapy at stroke onset [PDF]

open access: yes, 2010
<p><b>Background and Purpose:</b> Antiplatelets (APs) may increase the risk of symptomatic intracerebral hemorrhage (ICH) following intravenous thrombolysis after ischemic stroke.</p> <p><b>Methods:</b> We ...
Wahlgren, N.   +32 more
core   +1 more source

Thromboelastography evaluation of low response to clopidogrel in patients with acute coronary syndrome

open access: yesInternational Journal of Gerontology, 2018
Summary: Background: This study aims to measure platelet aggregation with thromboelastography (TEG) and observe low response to clopidogrel in patients with acute coronary syndrome (ACS) receiving dual antiplatelet therapy.
Lijia Zhao   +3 more
doaj   +1 more source

Outcome of stroke patients on clopidogrel plus proton-pump inhibitors: a single-center cohort study

open access: yesAnnals of Saudi Medicine, 2019
BACKGROUND: Recent studies suggest a higher risk of adverse cardiovascular outcome and mortality in patients co-prescribed clopidogrel with proton pump inhibitors (PPI). OBJECTIVE: Investigate the impact of concomitant prescription of clopidogrel and PPI
Rahaf A. Alghamdi   +4 more
doaj   +1 more source

Dramatic effect of early clopidogrel administration in reducing mortality and MACE rates in ACS patients

open access: yesSwiss Medical Weekly, 2012
BACKGROUND: Patients who have acute coronary syndromes with or without ST-segment elevation have high rates of major vascular events. We evaluated the efficacy of early clopidogrel administration (300 mg) (
Jean Christophe Stauffer   +5 more
doaj   +1 more source

Clopidogrel use After Myocardial Revascularization: Prevalence, Predictors, and One-Year Survival Rate

open access: yesBrazilian Journal of Cardiovascular Surgery
Introduction: Antiplatelet therapy after coronary artery bypass graft (CABG) has been used. Little is known about the predictors and efficacy of clopidogrel in this scenario. Objective: Identify predictors of clopidogrel following CABG.
Paulo Roberto L. Prates   +9 more
doaj   +1 more source

Influence of genetic polymorphisms in P2Y12 receptor signaling pathway on antiplatelet response to clopidogrel in coronary heart disease

open access: yesBMC Cardiovascular Disorders, 2022
Backgrounds Remarkable interindividual variability in clopidogrel response is observed, genetic polymorphisms in P2RY12 and its signal pathway is supposed to affect clopidogrel response in CHD patients.
Yan-Jiao Zhang   +6 more
doaj   +1 more source

The use of embolic signal detection in multicenter trials to evaluate antiplatelet efficacy: signal analysis and quality control mechanisms in the CARESS (Clopidogrel and Aspirin for Reduction of Emboli in Symptomatic carotid Stenosis) trial [PDF]

open access: yes, 2006
<p><b>Background and Purpose:</b> The CARESS (Clopidogrel and Aspirin for Reduction of Emboli in Symptomatic carotid Stenosis) trial proved the effectiveness of the combination of clopidogrel and aspirin compared with aspirin alone in ...
Ritter, M.A.   +9 more
core   +1 more source

A Comparison of Aspirin and Clopidogrel with or without Proton Pump Inhibitors for the Secondary Prevention of Cardiovascular Events in Patients at High Risk for Gastrointestinal Bleeding

open access: yes, 2011
Objective: This study was conducted to compare the risk of recurrent hospitalization for major gastrointestinal (GI) complications (peptic ulcer, bleeding, and perforation) in patients at high GI risk who require ongoing antiplatelet therapy (aspirin ...
蕭斐元;蔡憶文;黃文鴻;溫有汶;陳珮芬;郭耿南   +1 more
core   +1 more source

Interaction of Intraprocedural Antiplatelets and Intravenous Thrombolysis in Acute Intracranial Stenting: RESISTANT Registry Subanalysis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Introduction/Objective Acute intracranial stenting during endovascular thrombectomy (EVT) for ischemic stroke requires intraprocedural antiplatelet therapy (APT) to maintain patency. However, the hemorrhagic risk of combining APT with intravenous thrombolysis (IVT) remains uncertain.
Aaron Rodriguez‐Calienes   +75 more
wiley   +1 more source

Clopidogrel in Orthopaedic patients: a review of current practice in Scotland

open access: yesThrombosis Journal, 2007
Background Clopidogrel bisulfate is an antiplatelet agent used to prevent ischaemic events in patients with vascular disease. Current guidelines recommend withholding clopidogrel for 7 days pre-operatively.
Bramley Diane   +2 more
doaj   +1 more source

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