Results 11 to 20 of about 84 (84)

СONCOMITANT ADMINISTRATION OF CLOPIDOGREL AND PROTON PUMP INHIBITORS: ARE THERE ANY OPEN QUESTIONS LEFT TODAY?

Рациональная фармакотерапия в кардиологии, 2015
Concomitant administration of clopidogrel and proton pump inhibitors (PPI), the possible influence of PPI on the effectiveness of clopidogrel often raises questions among practitioners.
S. Yu. Martsevich, A. Yu. Suvorov
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A clinical case of acute coronary syndrome in patients with type 2 diabetes

Медицинский совет, 2015
The article reviews a clinical cases of acute coronary syndrome in a patient with type 2 diabetes (T2D). The causes of progression of atherosclerosis in patients with T2D are considered which leads to myocardial ischemia against a background of ...
S. V. Kakorin, E. N. Kononets
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INFLUENCE OF THE CYP3A4 ISOENZYME METABOLIC ACTIVITY AND CYP2C19 GENE POLYMORPHISMS ON CLOPIDOGREL ANTIPLATELET EFFECT IN PATIENTS WITH ACUTE CORONARY SYNDROME UNDERGOING PERCUTANEOUS CORONARY INTERVENTION

Рациональная фармакотерапия в кардиологии, 2015
Aim. Carriership of CYP2C19*2 allelic variant and reduced CYP3A4 activity can affect the formation of clopidogrel’s active metabolite and, respectively, its antiplatelet effect.
K. B. Mirzaev, R. E. Kazakov, V. V. Smirnov, D. A. Andreev, D. A. Sychev   +4 more
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Morphological determinants for the local hemostatic effect of exogenous fibrin monomer in its systemic administration after injury with inhibition of platelet aggregation in the experiment

Acta Biomedica Scientifica, 2023
Background. In our previously published studies, we demonstrated a high hemostatic activity of a low dose of exogenous fibrin monomer during its systemic administration in a model of dosed liver injury with preliminary inhibition of platelet aggregation.
V. M. Vdovin, E. V. Suzopov, I. I. Shakhmatov, I. P. Bobrov, D. A. Orekhov, A. Yu. Dolgatov, A. P. Momot   +6 more
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ДВОЙНАЯ АНТИТРОМБОЦИТАРНАЯ ТЕРАПИЯ: НЕОБХОДИМОСТЬ ПРИВЕРЖЕННОСТИ К ЛЕЧЕНИЮ И ВОЗМОЖНОСТИ ЕЕ ПОВЫШЕНИЯ

Атеротромбоз, 2014
Статья посвящена обсуждению вопросов приверженности к применению двойной антитромбоцитарной терапии (ДАТ) у пациентов, перенесших острый коронарный синдром (ОКС) или перенесших коронарное стентирование.

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EVALUATION OF PLATELET AGGREGATION IN CLINICAL PRACTICE

Рациональная фармакотерапия в кардиологии, 2015
Evaluation of platelet function with subsequent modification of antiplatelet therapy regimen is one of the areas of personalized medicine. Analysis of the causes of inadequate antiplatelet action of clopidogrel, the association of residual platelet ...
K. B. Mirzaev, D. A. Andreev, D. A. Sychev   +2 more
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THE ROLE OF MODERN ANTIPLATELET THERAPY IN PREVENTION OF ATHEROTHROMBOSIS: THE IMPORTANCE OF CLOPIDOGREL AND ITS GENERIC DRUGS

Рациональная фармакотерапия в кардиологии, 2016
Current issues of atherothrombosis prevention and treatment optimization with antiplatelet therapy in patients with cardioascular diseases are discussed.
O. V. Gaisenok
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THERAPEUTIC EQUIVALENCE OF ORIGINAL CLOPIDOGREL (PLAVIX) AND ITS GENERIC (EGITROMB). RESULTS OF COMPARATIVE RANDOMIZED CROSS-OVER BLIND STUDY

Рациональная фармакотерапия в кардиологии, 2016
Aim. To study therapeutic equivalence (efficacy, safety and tolerability) of original clopidogrel (Plavix) and its generic (Egitromb) in patients of high cardiovascular risk. Material and methods.
V. V. Yakusevich, A. S. Petrochenko, V. A. Simonov, N. Yu. Levshin, A. D. Deev   +4 more
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Patient-specific choice of an antiplatelet drug for long-term therapy of coronary heart disease: rationale and implementationL

Медицинский совет, 2014
In all urbanized countries, more than half of overall mortality is conditioned by diseases caused by atherothrombosis in the arteries of heart and brain.
NA Mazur
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Role of clopidogrel role in secondary prevention of ischemic stroke

Медицинский совет, 2014
The article tells discusses the role of antiplatelet therapy in the prevention of atherothrombotic stroke. There is data from large randomized studies which compared the effects of clopidogrel and acetylsalicylic acid drugs in reducing the risk of stroke.
K. S. Meshkova, V. V. Gudkova
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