Results 191 to 200 of about 50,242 (223)
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2019
Рданной ÑабоÑе иÑÑÐ»ÐµÐ´Ð¾Ð²Ð°Ð½Ñ ÑÑовни ÑкÑпÑеÑÑии калÑÑий ÑвÑзÑваÑÑÐ¸Ñ Ð±ÐµÐ»ÐºÐ¾Ð² в гиппокампе мÑÑей моделей болезни ÐлÑÑгеймеÑа APPPSEN1dE9. Ðо ÑезÑлÑÑаÑам ÐеÑÑеÑн-Ð±Ð»Ð¾Ñ Ð°Ð½Ð°Ð»Ð¸Ð·Ð° в гиппокампе мÑÑей APPPSEN1dE9 Ñ ...
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Рданной ÑабоÑе иÑÑÐ»ÐµÐ´Ð¾Ð²Ð°Ð½Ñ ÑÑовни ÑкÑпÑеÑÑии калÑÑий ÑвÑзÑваÑÑÐ¸Ñ Ð±ÐµÐ»ÐºÐ¾Ð² в гиппокампе мÑÑей моделей болезни ÐлÑÑгеймеÑа APPPSEN1dE9. Ðо ÑезÑлÑÑаÑам ÐеÑÑеÑн-Ð±Ð»Ð¾Ñ Ð°Ð½Ð°Ð»Ð¸Ð·Ð° в гиппокампе мÑÑей APPPSEN1dE9 Ñ ...
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2019
In this study was investigated the role of piperazine derivative 51164 on the activity of TRPC6 channels expressed in HEK293T cells. It was shown that 51164 is an agonist of TRPC6 channels, activating the cationic current into the cell by means of patch-clamp. A comparison of 51164 with hyperforin agonist was also carried out.
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In this study was investigated the role of piperazine derivative 51164 on the activity of TRPC6 channels expressed in HEK293T cells. It was shown that 51164 is an agonist of TRPC6 channels, activating the cationic current into the cell by means of patch-clamp. A comparison of 51164 with hyperforin agonist was also carried out.
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2023
The anti-apoptotic protein Bcl-2 is an intracellular regulator of calcium signaling, impaired in Alzheimers disease neurons. This work is devoted to the study of the effect of Bcl-2 protein overexpression in hippocampal neurons on the morphology of dendritic spines and recognition memory in the âNovel object recognitionâ test in 5xFAD mice ...
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The anti-apoptotic protein Bcl-2 is an intracellular regulator of calcium signaling, impaired in Alzheimers disease neurons. This work is devoted to the study of the effect of Bcl-2 protein overexpression in hippocampal neurons on the morphology of dendritic spines and recognition memory in the âNovel object recognitionâ test in 5xFAD mice ...
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2020
The work is devoted to study the dynamics of the astrocyte protein genes (GFAP, IP3R2, EAAT2, IL-1β, and TNFα) expression in rat brain in experimental models of epilepsy.The study was performed in the Laboratory of molecular mechanisms of neural interactions, IEPhB RAS.
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The work is devoted to study the dynamics of the astrocyte protein genes (GFAP, IP3R2, EAAT2, IL-1β, and TNFα) expression in rat brain in experimental models of epilepsy.The study was performed in the Laboratory of molecular mechanisms of neural interactions, IEPhB RAS.
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2023
In addition to the main anti-apoptotic function, Bcl-2 protein regulates the intracellular calcium metabolism. In this paper, the effect of Bcl-2 protein overexpression in hippocampal neurons on the accumulation of amyloid plaques in the brain and spatial memory in the Morris water maze test of 5xFAD Alzheimers disease model mice was analyzed.
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In addition to the main anti-apoptotic function, Bcl-2 protein regulates the intracellular calcium metabolism. In this paper, the effect of Bcl-2 protein overexpression in hippocampal neurons on the accumulation of amyloid plaques in the brain and spatial memory in the Morris water maze test of 5xFAD Alzheimers disease model mice was analyzed.
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2017
Ð ÑабоÑе иÑÑледовано влиÑние ÑкÑпÑеÑÑии белка HAP1A (Huntingtin-associated protein 1 A) на депо-ÑпÑавлÑемÑй Ð²Ñ Ð¾Ð´ калÑÑÐ¸Ñ Ð² клеÑÐºÐ°Ñ Ð½ÐµÐ¹ÑоблаÑÑÐ¾Ð¼Ñ Ñеловека SK-N-SH, моделиÑÑÑÑÐ¸Ñ Ð±Ð¾Ð»ÐµÐ·Ð½Ñ Ð¥Ð°Ð½ÑингÑона пÑÑем ÑкÑпÑеÑÑии
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Ð ÑабоÑе иÑÑледовано влиÑние ÑкÑпÑеÑÑии белка HAP1A (Huntingtin-associated protein 1 A) на депо-ÑпÑавлÑемÑй Ð²Ñ Ð¾Ð´ калÑÑÐ¸Ñ Ð² клеÑÐºÐ°Ñ Ð½ÐµÐ¹ÑоблаÑÑÐ¾Ð¼Ñ Ñеловека SK-N-SH, моделиÑÑÑÑÐ¸Ñ Ð±Ð¾Ð»ÐµÐ·Ð½Ñ Ð¥Ð°Ð½ÑингÑона пÑÑем ÑкÑпÑеÑÑии
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2021
Ð ÑбоÑнике пÑедÑÑÐ°Ð²Ð»ÐµÐ½Ñ Ð¼Ð°ÑеÑÐ¸Ð°Ð»Ñ 3-й ÐеждÑнаÑодной наÑÑно-пÑакÑиÑеÑкой конÑеÑенÑии «ÐолекÑлÑÑно-генеÑиÑеÑкие ÑÐµÑ Ð½Ð¾Ð»Ð¾Ð³Ð¸Ð¸ анализа ÑкÑпÑеÑÑии генов пÑодÑкÑивноÑÑи и ÑÑÑойÑивоÑÑи к заболевани
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Ð ÑбоÑнике пÑедÑÑÐ°Ð²Ð»ÐµÐ½Ñ Ð¼Ð°ÑеÑÐ¸Ð°Ð»Ñ 3-й ÐеждÑнаÑодной наÑÑно-пÑакÑиÑеÑкой конÑеÑенÑии «ÐолекÑлÑÑно-генеÑиÑеÑкие ÑÐµÑ Ð½Ð¾Ð»Ð¾Ð³Ð¸Ð¸ анализа ÑкÑпÑеÑÑии генов пÑодÑкÑивноÑÑи и ÑÑÑойÑивоÑÑи к заболевани
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Діяльнісний підхід як основний критерій ефективності навчання
Нові технології навчанняСтаттю присвячено розгляду аналізу, узагальненню та описанню того, як, використовуючи діяльнісний підхід, потрібно на науковій основі робити висновки про ефективність навчання.
Борис Кремінський +3 more
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This work is devoted to determining the effect of CRISPR interference on the expression of the ftsA and ftsZ genes in M. gallisepticum. Tasks that were solved during the research: 1. To develop a sample preparation protocol that allows to obtain cultures of different M. gallisepticum strains in the same growth phase; 2.
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ПОЛІТИЧНИЙ РИЗИК ЯК КРИТЕРІЙ ФУНКЦІОНАЛЬНОСТІ ПОЛІТИЧНОЇ СИСТЕМИ
Вісник Прикарпатського університету. Серія: ПолітологіяУ статті політичний ризик розглядається як ключовий критерій функціональності політичної системи в умовах зростання невизначеності, соціально-політичних трансформацій і воєнних викликів.
Юлія Кобець
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