Results 71 to 80 of about 569 (87)

Assessment of the influence of demographic and anthropometric indicators on the variability of pharmacokinetic parameters

Фармакокинетика и Фармакодинамика
Relevance. Planning the design of bioequivalence clinical studies of generic highly variable drugs requires non-standard approaches – the use of replicative (repeated) or adaptive design.
V. B. Vasilyuk, A. B. Verveda, M. V. Faraponova, G. I. Syraeva   +3 more
doaj   +1 more source

Main strategies of plant expression system glycoengineering for producing humanized recombinant pharmaceutical proteins

, 2020
В настоящее время большинство белков фармацевтического назначения получают не из первичных источников, а путем синтеза их рекомбинантных аналогов в различных системах экспрессии.
Дейнеко, Елена Викторовна, Пермякова, Наталья Владиславовна, Розов, Сергей Михайлович   +2 more
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Quantum analysis of pharmacodynamics in phytotherapy - research results

, 2017
В механизма на лекарствено действие се търсят и изследват взаимодействията на лекарствените молекули с определени биологични структури. Въведеният от нас квантов анализ с „Принцип на подобието` дава възможност за едно ясно теоретично и практически ...
Kaniskov, V.; NAA - Sofia, Krastev, K.; Vasil Levski NMU - Veliko Tarnovo   +1 more
core   +1 more source

Effect of cyclo-L-prolylglycine on pain response thresholds and morphine-induced analgesia in inbred BALB/c and C57Bl/6 mice

Фармакокинетика и Фармакодинамика
Relevance. Cyclo-L-prolylglycine (CPG), discovered as an endogenous compound in the central nervous system, is involved in the formation of a reaction to emotional stress in rodents with a pronounced fear reaction and has an analgesic effect in vivo ...
A. V. Nadorova, K. N. Koliasnikova, I. V. Chernyakova, L. G. Kolik   +3 more
doaj   +1 more source

Острое отравление этиловым алкоголем (алкогольная кома)

, 2019
The article summarizes years of the authors experience in the diagnosis and treatment of acute poisonings with ethyl alcohol and presents data on the epidemiology of poisoning with ethyl alcohol, as well as modern terminology and systematization of ...
Y. S. Goldfarb, V. N. Alexandrovsky, Y. N. Ostapenko, В. Н. Александровский, Ю. С. Гольдфарб, M. V. Kareva, Ю. Н. Остапенко, М. В. Карева, M. M. Potskhveriya, М. М. Поцхверия   +9 more
core   +1 more source

Ferroptosis and ageing

Фармакокинетика и Фармакодинамика
Ferroptosis is a regulated form of cell death characterized by iron-dependent lipid peroxidation. Since its initial description, it has garnered significant attention due to its implications in various diseases, including cancer, neurodegeneration, and ...
A. A. Garanin, T. E. Bogacheva, O. A. Gromova   +2 more
doaj   +1 more source

Ингибиторы ангиотензинпревращающего фермента в терапевтической клинике [PDF]

, 2009
Описана клиническая фармакология ингибиторов ангиотензинпревращающего фермента (ИАПФ) в рамках классификационной системы АТС. Представлена клиническая классификация, фармакокинетика и фармакодинамика препаратов.
Мартимьянова, Л.А., Власенко, О.А., Савченко, В.Н., Мальцева, М.С.   +3 more
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Study of the possibility of using metformin by intranasal administration for the correction of behavioral and cognitive dysfunctions of rats

Фармакокинетика и Фармакодинамика
Relevance. Metformin is an antidiabetic agent in the therapy of type 2 diabetes mellitus, which has a complex of pharmacological effects that may allow its use as a geroprotector and a means for the treatment of cognitive and behavioral disorders ...
A. Z. Hafizova, I. I. Semina
doaj   +1 more source

Valsartan pharmacokinetics in patients with controlled and uncontrolled arterial hypertension

Фармакокинетика и Фармакодинамика
Relevance. Arterial hypertension (AH) is widespread throughout the world. Unfortunately, only a small proportion of patients achieve target blood pressure (BP).
S. V. Seleznev, P. Yu. Mylnikov, A. V. Shchulkin   +2 more
doaj   +1 more source

Main strategies of plant expression system glycoengineering for producing humanized recombinant pharmaceutical proteins

, 2018
В настоящее время большинство белков фармацевтического назначения получают не из первичных источников, а путем синтеза их рекомбинантных аналогов в различных системах экспрессии.
Дейнеко, Елена Викторовна, Пермякова, Наталья Владиславовна, Розов, Сергей Михайлович   +2 more
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