Results 81 to 90 of about 5,396 (178)

Autophagy Orchestrates Anti‐Tumor Immunity to Enhance Chemosensitivity via the FBXW2/C/EBPβ/TIMP‐2 Axis in Colorectal Cancer

Advanced Science, EarlyView.
Chemotherapy leverages tumor‐cell autophagy to reshape the colorectal cancer immune microenvironment. Autophagy degrades FBXW2 to promote C/EBPβ‐mediated TIMP‐2 transcription and MMP‐9 suppression, driving intra‐tumoral CD8+ T‐cell infiltration. Targeting MMP‐2/9 or restoring TIMP‐2 overcomes chemo‐resistance in autophagy‐deficient tumors. ABSTRACT The
Bing Cheng, Chaoying Wei, Zhitong Niu, Jinxin Chen, Guojie Long, Yingzhen Weng, Qiufeng Liu, Yue Jiang, Panpan Wang, Ronghua Zhang, Qiang Yu, Xiaojian Wu, Wenyu Wang   +12 more
wiley   +1 more source

HIỆU QUẢ CỦA DỊCH CHIẾT BẠC HÀ, SẢ VÀ BẠCH ĐÀN ĐỐI VỚI VI KHUẨN Ralstonia solanacearum GÂY BỆNH HÉO XANH TRÊN TRÊN CÂY ỚT [PDF]

, 2019
Tóm tắt: Bệnh héo xanh do vi khuẩn Ralstonia solanacearum (Smith) Yabuuchilà một trong những bệnh quan trọng trên cây ớt, gây thiệt hại lớn về kinh tế và rất khó phòng trị.
Vũ, Trần Anh, Toàn, Lê Thanh
core   +1 more source

A Magnetic‐Driven Self‐Rotation‐Stabilized Miniature Swimming Robot

Advanced Science, EarlyView.
Inspired by the stable rotational descent of seeds in nature, this study designs a magnetic‐driven self‐rotation‐stabilized miniature swimming robot (MSMSR). Based on a resonance‐driven strategy, the robot exhibits high swimming performance, offering enhanced directional swimming and improved resistance to water flow disturbances compared to existing ...
Fujun Wang, Chuhan Zhang, Hao Zhang, Yanling Tian, Cunman Liang   +4 more
wiley   +1 more source

Phân lập và tuyển chọn chủng vi khuẩn thuộc nhóm Bacillus subtilis có khả năng đối kháng tốt với nấm Colletotrichum scovillei gây bệnh thán thư trên ớt ở Thành phố Hồ Chí Minh [PDF]

, 2020
Chilli anthracnose disease caused by Colletotrichum spp. has heavily damaged the quality and yield production of chili around the world. In Viet Nam, many chili growing regions namely Ho Chi Minh City have been enormously affected by the disease for many
Xô, Dương Hoa, Hoàng, Phạm Nguyễn Đức, Trang, Trần Thùy, Nguyệt, Nguyễn Thị Ánh, Châm, Lê Thị Mai, Đức, Nguyễn Tấn   +5 more
core   +1 more source

Ontogenesis of oxytocin pathways in the mammalian brain: late maturation and psychosocial disorders

Frontiers in Neuroanatomy, 2015
Oxytocin (OT), the main neuropeptide of sociality, is expressed in neurons exclusively localized in the hypothalamus. During the last decade, a plethora of neuroendocrine, metabolic, autonomic and behavioral effects of OT has been reported.
Valery eGrinevich, Michel eDesarménien, Bice eChini, Maithé eTauber, Françoise eMuscatelli   +4 more
doaj   +1 more source

Predicting Single‐Cell Perturbation Responses Across Biological Contexts With a Deep Generative Model Integrating Optimal Transport

Advanced Science, EarlyView.
Single‐cell perturbation responses are predicted across held‐out biological contexts using scPILOT, a query‐conditioned two‐stage latent response‐transfer framework. A shared latent representation supports cell‐level response estimation by latent optimal transport, followed by Leiden‐localized query‐specific transfer and adaptive weighting.
Jialiang Wang, Ziqi Liu, Zhengqian Zhang, Yikun Cao, Junjun Ren, Peng Cheng, Jingjing Tian, Lingyun Xie, Xin Lu, Zhanwei Du, Yongzhuang Liu   +10 more
wiley   +1 more source

Intestinal transepithelial permeability of oxytocin into the blood is dependent on the receptor for advanced glycation end products in mice

Scientific Reports, 2017
Plasma oxytocin (OT) originates from secretion from the pituitary gland into the circulation and from absorption of OT in mother’s milk into the blood via intestinal permeability.
Haruhiro Higashida, Kazumi Furuhara, Agnes-Mikiko Yamauchi, Kisaburo Deguchi, Ai Harashima, Seiichi Munesue, Olga Lopatina, Maria Gerasimenko, Alla B. Salmina, Jia-Sheng Zhang, Hikari Kodama, Hironori Kuroda, Chiharu Tsuji, Satoshi Suto, Hiroshi Yamamoto, Yasuhiko Yamamoto   +15 more
doaj   +1 more source

The organizational effects of oxytocin on the central expression of estrogen receptor α and oxytocin in adulthood

BMC Neuroscience, 2007
Background Previous studies have demonstrated that neonatal manipulation of oxytocin (OT) has effects on the expression of estrogen receptor α (ERα) and the central production of oxytocin observed in juveniles (at weaning, 21 days of age).
Papademetriou Eros, Yoshida Shigeto, Kramer Kristin M, Cushing Bruce S   +3 more
doaj   +1 more source

Efficacy of CaCl2 against some important postharvest fungi on orange, chilli and Cavendish banana fruits: Hiệu quả của CaCl2 đối với một số loại nấm quan trọng gây hại sau thu hoạch trên trái cam, ớt và chuối già [PDF]

, 2018
Fruit rot caused by Aspergillus niger or Colletotrichum musae is an important post-harvest disease on orange, chilli and Cavendish banana fruits. The use of synthetic fungicides has been a traditional strategy for the management of the fruit rot disease,
Trieu, Phuong Linh, Ngo, Van Toan, Nguyen, Huy Hoang, Vo, Trong Ky, Nguyen, Thi My Linh, Le, Thanh Toan   +5 more
core   +1 more source

Macrophage Trogocytosis of Tumor Cells Drives the Immunosuppression of Tumor Microenvironment

Advanced Science, EarlyView.
Trogocytosis efficiency varies significantly among different tumor cells and is inversely related to their cortical stiffness; this efficiency dictates the extent of immunosuppression via upregulation of CXCL5 and Arg‐1, ultimately driving CD8+T cell exhaustion and tumor escape.
Chao Liang, Jiaqi He, Wan‐Ru Zhuang, Yao Lei, Yanru Jiang, Xianbin Ma, Pan Liu, Zhujun Jiang, Yongheng Li, Hai‐Yan Xie   +9 more
wiley   +1 more source