Results 101 to 110 of about 115,028,515 (254)
ACADEMIC WRITING OFFICE OF SOUTH URAL STATE UNIVERSITY: GOALS, STRUCTURE, FUNCTIONING
Высшее образование в России, 2017 The article focuses on describing the structure and functional characteristics ofthe Academic Writing Office of South Ural State University (National Research University), member of the project 5-100, which provides for increasing competitive ability of ...
M. A. Chernysheva +2 more
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Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
Philanthropy Project. 1986 Minnesota Foundations List. [PDF]
, 1986 Philanthropy Project. (1986). Philanthropy Project. 1986 Minnesota Foundations List..
Philanthropy Project
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Molecular Oncology, EarlyView.Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
wiley +1 more source
Valdosta Project Change, Scrapbook, May 1998 [PDF]
, 1998 Valdosta Project Change. “Valdosta Project Change Scrapbook, May 1998,” Lowndes County Historical Society. Valdosta State University Archives and Special Collections, MS-181: Valdosta Project Change Collection, 1997-2023.
Valdosta Project Change
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Molecular Oncology, EarlyView.The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington +10 more
wiley +1 more source
Research on imaging detection technology for 10–100 keV medium-energy electrons
Earth and Planetary PhysicsElectrons in the energy range of 10–100 keV are important energetic particle components in the magnetosphere, and they play a key role in many physical processes in the magnetosphere.
JiaChen Sun +5 more
doaj +1 more source
Molecular Oncology, EarlyView.Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
Development of Performance Properties of Ternary Mixtures: Field Demonstrations and Project Summary, TPF-5(117), 2012 [PDF]
, 2012 Supplementary cementitious materials (SCM) have become common parts of modern concrete practice. The blending of two or three cementitious materials to optimize durability, strength, or economics provides owners, engineers, materials suppliers, and ...
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