Results 111 to 120 of about 115,028,515 (254)

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

Molecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang, Hyung Seok Kim, Geum Ok Baek, Moon Gyeong Yoon, Su In Lee, Jee‐Yeong Jeong, Ji Eun Han, Soon Sun Kim, Jae Youn Cheong, Jung Woo Eun   +9 more
wiley   +1 more source

2016 Self, Motivation & Virtue Project Conference Highlights

, 2016
This video features highlights from the 2016 Self, Motivation & Virtue Project Conference, held on May 5-7, 2016 at the University of Notre Dame in South Bend, Indiana.
The Self, Motivation & Virtue Project
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Essential Functionalities of ERA-NET Electric Mobility Europe PLATON Project

Механика машин, механизмов и материалов, 2018
The paper is an extension of the same name plenary report at the conference “Innovations in mechanical engineering-2018”, which has been held in Minsk, Belarus, on September 18–19, 2018.
Vladimir B. Algin, Olaf Czogalla, Mikhail Ya. Kovalyov, Krzysztof Krawiec, Sergey Chistov   +4 more
doaj  

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source

An investigation of linting and fluffing of offset newsprint. Project 2949, report five : a progress report to members of group project 2949.

, 1975
"May 16, 1975.""Members of the group project 2949: Bowaters Southern Paper Corp., International Paper Company, Southwest Forest Industries, Inc.""The Institute of Paper Chemistry, Betty John ... Russell F. Tyler... Robert M. Leekley ... John W. Swanson.
John, Betty M., Swanson, John W., Leekley, Robert M., Tyler, Russell F.   +3 more
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Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

Molecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou, Niki Tzenaki, Anna Tsapara, Maria Tzardi, Evangelia A. Papakonstanti   +4 more
wiley   +1 more source

I-5 Rose Quarter Improvement Project independent cover assessment

, 2020
[Report] -- Appendix A. ESC Values and Outcomes -- Appendix B. Community Cohesion Review -- Appendix C. Development Potential Review -- Appendix D. Urban Design Memo​ -- Appendix E. Technical Design Assessment​ -- Appendix F.

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ORGANIZATIONAL CHANGE AT UNIVERSITY FOR REACHING THE STRATEGIC DEVELOPMENT GOAL

Высшее образование в России, 2016
The paper presents the case study of strategic organizational change in Lobachevsky State University of Nizhni Novgorod, a participant of the «5-100 Program».
Alexander O. Grudzinskiy, Evgeniy V. Chuprunov   +1 more
doaj  

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

Molecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic, Rafael Stroggilos, Mladen Marinkovic, Ana Djuric, Suzana Stojanovic‐Rundic, Radmila Jankovic, Sergi Castellvi‐Bel, Remond J.A. Fijneman, Antonia Vlahou, Jerome Zoidakis, Milena Cavic   +10 more
wiley   +1 more source