Results 21 to 30 of about 140 (140)

Analyzing the Reproductive Characteristics of the Naked Carp Gymnocypris Przewalskii (Kessler) Based on the Oxygen Isotopes of Otolith Core Using SHRIMP

Yankuang ceshi, 2023
BACKGROUNDIt is of great significance to study the breeding environment of the naked carp in Qinghai Lake for the conservation and restoration of natural habitat. The naked carp is the only economic species in Qinghai Lake, colloquially called “Huang Yu”,
Ling ZHOU, Linbo QIAN, Sumei ZHAO, Xiulan ZHANG, Yinglie LIU, Qiaoling TANG, Jie YUAN   +6 more
doaj   +1 more source

Molten Uranium Breeder Reactor (MUBR) and Its Development Steps [version 2; peer review: 2 approved]

Nuclear Science and Technology Open Research
Background The Molten Uranium Breeder Reactor (MUBR) is a radical new mixed-energy spectrum breed and burn reactor concept. The MUBR is fueled with molten uranium metal fuel in large fuel tubes instead of thin fuel rods, and is cooled by circulating the ...
Neal Mann, Mihai (Mike) G. M. Pop, Zeyun Wu   +2 more
doaj   +1 more source

Review: Impact of Food and Climate Change on Pastoral Industries

Frontiers in Sustainable Food Systems, 2020
The industrialization of agriculture based on inexpensive fossil fuels allowed for unprecedented levels of food production and population growth, but simultaneously contributed to a threat to food systems and population well-being: climate change.
Md E. Uddin, Ermias Kebreab
doaj   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Effectiveness evaluation of application of niosomal gel "Regenerin" in the treatment of chemical burns of cornea [PDF]

Саратовский научно-медицинский журнал, 2017
The aim of the work was to study the effectiveness of using the ophthalmic gel "Regenerin" in the treatment of a simulated chemical burn of the cornea in an experiment. Material and Methods. The chemical composition of the drug "Regenerin" was studied by
Bazikov I.A., Botasheva V.S., Kalinkina N.I., Maltsev A.N., Kostyukova N.Yu., Domenyuk D. A.   +5 more
doaj  

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

Harnessing Manuka Honey: A Natural Remedy for Accelerated Burn Wound Healing in a Porcine Model

Pharmaceuticals
Backgrounds: Burn injuries present significant medical challenges due to their complexity in healing and potential for severe scarring. This study evaluates the efficacy of Manuka honey in accelerating burn wound healing compared to conventional ...
Boris Privrodski, Mladen Jovanović, Nikola Delić, Radomir Ratajac, Vladimir Privrodski, Aleksandar Stanojković, Bernadeta Gavlik, Ivan Čapo   +7 more
doaj   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source