Results 31 to 40 of about 140 (140)

The C‐terminal region of KIF26B is indispensable for nephron progenitor condensation and kidney formation in mice

FEBS Open Bio, EarlyView.
KIF26B plays an important role in kidney development. We engineered mice lacking the C‐terminal region of KIF26B and found severe kidney defects, including bilateral renal agenesis, similar to full Kif26b knockout mice. The mutation disrupted nephron progenitor condensation and reduced Gdnf‐Wnt11 signaling, showing that the KIF26B C‐terminal region is ...
Yuta Yamamura, Kengo Furuichi, Hiromitsu Akamatsu, Naoki Yamamoto, Sako Keisuke, Akihiko Koshino, Taichiro Minami, Megumi Oshima, Akinori Hara, Norihiko Sakai, Miho Shimizu, Kenta Takahashi, Minako Yamamura, Shin‐ichi Horike, Takiko Daikoku, Kenichi Harada, Yohei Shinmyo, Hiroshi Kawasaki, Takashi Wada, Yasunori Iwata   +19 more
wiley   +1 more source

Differences in the relationship between tibia breaking strength and ash in two fast-growing commercial strains of broiler

Journal of Applied Poultry Research
Summary: Leg problems are one of the biggest welfare and financial challenges in chicken farming. When researchers want to check how strong a chicken’s bones are, they typically use one of two tests: they either physically snap the bone to measure how ...
Gregory S. Archer
doaj   +1 more source

TERRAPOWER, LLC TRAVELING WAVE REACTOR DEVELOPMENT PROGRAM OVERVIEW

Nuclear Engineering and Technology, 2013
Energy security is a topic of high importance to many countries throughout the world. Countries with access to vast energy supplies enjoy all of the economic and political benefits that come with controlling a highly sought after commodity.
PAVEL HEJZLAR, ROBERT PETROSKI, JESSE CHEATHAM, NICK TOURAN, MICHAEL COHEN, BAO TRUONG, RYAN LATTA, MARK WERNER, TOM BURKE, JAY TANDY, MIKE GARRETT, BRIAN JOHNSON, TYLER ELLIS, JON MCWHIRTER, ASH ODEDRA, PAT SCHWEIGER, DOUG ADKISSON, JOHN GILLELAND   +17 more
doaj   +1 more source

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

FEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin, Naghme Radmannia, David N. Huynh, Liliane Ménard, Caroline Daneault, Maïté Veilleux, Ahsanullah Ahsanullah, André C. Carpentier, William D. Lubell, Matthieu Ruiz, Huy Ong, Sylvie Marleau, Simon‐Pierre Gravel   +12 more
wiley   +1 more source

How phagocytic cells kill bacteria: Lessons from a professional killer

FEBS Open Bio, EarlyView.
How phagocytic cells ingest and kill bacteria has been studied for more than a century, but many questions remain unanswered. The study of the amoeba Dictyostelium discoideum brings new answers, and new questions. Professional phagocytic cells such as neutrophils and macrophages, as well as free‐living soil amoebae like Dictyostelium discoideum, employ
Otmane Lamrabet, Pierre Cosson
wiley   +1 more source

Avidin is evolutionarily conserved in fish but dispensable for development and resistance against Streptococcus agalactiae in zebrafish

FEBS Open Bio, EarlyView.
The presence of biotin‐binding avidin proteins in fish and their biological significance are poorly characterized. We cataloged fish avidins and demonstrate that they are widely present and evolutionarily conserved. We created avd knockout zebrafish and show that zebavidin is dispensable for development and that resistance of avd knockout embryos in ...
Anni K. Saralahti, Markus J. T. Ojanen, Mataleena Parikka, Otto Kauko, Mika Rämet, Vesa P. Hytönen   +5 more
wiley   +1 more source

Estimate of genetic parameters for carcass traits and visual scores inmeat sheep using Bayesian inference via threshold and linear models

Ciência Rural
: The aim of this study was to estimate the variance components and genetic parameters for marbling in the ribeye area (MRA) and body condition score (BCS) using Bayesian inference via mixed linear and threshold animal models.
Luiz Antonio Silva Figueiredo Filho, José Lindenberg Rocha Sarmento, Alan Oliveira do Ó, Natanael Pereira da Silva Santos, Luciano Silva Sena, Antonio de Sousa Júnior   +5 more
doaj   +1 more source

ALDOA Promotes Glycolysis and NLRP3/GSDMD Pyroptosis to Accelerate ALS Progression

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is characterized by progressive motor neuron degeneration. Glycolytic dysregulation is implicated in disease progression, yet the underlying mechanisms remain unclear. This study investigates how Aldolase A (ALDOA) drives ALS progression through glycolysis‐mediated motor neuron pyroptosis.
Kaixin Yan, Yan Jiang, Yuxuan Yong, Tianshuo Zhang, Niannian Zhang, Qianqian Zeng, Xue Gong, Li Meng, Fangfang Bi, Yongmin Liu   +9 more
wiley   +1 more source

Nuclide inventory analysis and fission product monitoring for nuclear safeguards in molten chloride fast reactors

Nuclear Engineering and Technology
Fission product analysis offers a powerful means to real-time monitoring of fissile material evolution and sudden alterations in Molten Chloride Fast Reactors, where conventional safeguards techniques are challenged by continuously circulating fuel.
Saehyun Choi, Jeongwon Seo, Wonseok Yang, Jihun Kim, Taehoon Park, Sujeong Lee, Sungyeol Choi   +6 more
doaj   +1 more source

Semiconducting Polymers Post‐Functionalized With Ureido‐Pyrimidinone for Robust Stretchable Transistors

Advanced Functional Materials, EarlyView.
The design of intrinsically robust stretchable semiconducting polymers was achieved through OTBS‐mediated post‐functionalization of PDPP2T side chains with UPy units, generating dual hydrogen‐bonding motifs comprising weaker urethane linkages and strong quadruple UPy interactions along the long alkyl side chain, which is crucial for achieving desirable
Dinda Bazliah, Livy Laysandra, Kosuke Terayama, Xingyu Yang, Atsushi Isobe, Tai‐Chin Chiang, Tsuyoshi Michinobu, Yu‐Cheng Chiu   +7 more
wiley   +1 more source