Application of evolocumab in patients with coronary heart disease complicated with mild renal insufficiency [PDF]
, 2023 Objective To evaluate the efficacy and safety of evolocumab， a proprotein convertase subtilisin/kexin type 9 （PCSK9） inhibitor， in lowering LDL-C levels in patients with coronary heart disease complicated with mild renal insufficiency.
Zhang Yu, Wu Bin, Feng Jiaxu, Wang Rutao, Yuan Ming
core +1 more source
Development of a Personalized Pharmacologic Treatment Repository for Bronchial Asthma Based on the 2018 Guideline for the Diagnosis and Management of Bronchial Asthma in Primary Care（Practice Edition） [PDF]
, 2022 Bronchial asthma is a chronic inflammatory disease with high heterogeneity, polygenic inheritance, complex etiology and many complications. The effects of prevention and treatment for a bronchial asthma patient often depend on whether the patient has ...
HUO Hongmin, YANG Yaofang, DONG Jiatian, MAO Zixian, HU Ping, SONG Fengchun
core +1 more source
A Real-world Data Study on Comprehensive Control Rates in a Large Population of Type 2 Diabetes Patients [PDF]
, 2022 BackgroundThere are differences between RCTs and real-world data in reporting the rate of clinical control of patients with diabetes, which cannot solve the problem of continuous observation in large-scale populations.
HUANG Jingyuan, HUANG Yanli
core +1 more source
Research Progress of Pericoronary Adipose Tissue Radiomics Based on Coronary Computed Tomography Angiography [PDF]
Pericoronary adipose tissue (PCAT) is a type of adipose tissue tightly wrapped in the adventitia of the coronary artery, which communicates bidirectionally with the coronary artery wall and promotes the development of coronary atherosclerosis during ...
Jianhua ZHAO, Xin YAN
core +1 more source
, 2012 炎症在动脉粥样硬化(AS)中扮演重要的角色。炎症贯穿于疾病发生、发展的各个阶段,包括易损粥样斑块形成和最终的破裂。其过程涉及许多炎性细胞,如单核细胞源性巨噬细胞、T淋巴细胞及其合成和分泌的细胞因子、趋化因子和酶。这些炎性因子导致内皮细胞活化,平滑肌细胞增殖,纤维帽基质的降解而形成易损斑块。这些有关炎性因子通过各种方法可从外周血检测到,且循环血液中的炎症因子浓度与将来的心血管事件的发生密切相关 ...
王焱, 袁平年
core
Relationship between Depression,Anxiety and Cardiac Events after Coronary Artery Bypass Grafting [PDF]
, 2009 目的:前瞻、序列、对比研究我科行冠状动脉旁路移植术(coronary artery bypass grafting,CABG)的患者术后1年抑郁、焦虑的状况以及心血管事件的发生率。方法:2005年10月至2006年8月,以我科连续行择期CABG术的69例患者为对象,分别在术前1周内、术后出院前1天、术后1年使用ZUNG氏抑郁自评量表和焦虑自评量表进行抑郁、焦虑状态评分,同时随访术后1年的心血管事件的发生率。结果:术前24例(34.8%)存在抑郁焦虑状态,出院前33例(47.8%)存在抑郁焦虑状态 ...
李西慧, 王忠杰, 高文斌
core
The Study of Relationship Between Plasma Ceruloplasmin and Coronary Artery Plaque Stability in Patients with Coronary Heart Disease [PDF]
, 2012 目的：冠状动脉易损斑块的破裂是发生急性冠脉综合征（acutecoronarysyndrome，ACS）的主要原因，其中炎症反应在动脉粥样硬化中扮有重要的角色，包括易损斑块的形成和最终的破裂。本研究的主要目的是；通过灰阶血管内超声（intravascularultrasound，IVUS）和虚拟组织学血管内超声（virtualhistologyintravascularultrasound，VH-IVUS），探讨稳定性心绞痛（stableanginapectoris，SAP ...
袁平年
core
Expert Consensus on Screening and Prevention of Diabetic Microvascular Disease for Primary Care (2024) [PDF]
Diabetic microvascular disease (DMiVD) is the most common chronic complication of diabetes mellitus, and early identification and effective intervention can significantly improve patients' quality of life and prognosis.
Diabetes and Microcirculation Professional Committee of Chinese Society of Microcirculation, Primary Endocrine and Metabolic Diseases Group of the Chinese Society of Endocrinology
core +1 more source
重要性早期预警评分预测急性冠脉综合征住院患者心脏骤停效果评价 [PDF]
, 2018 目的探讨重要性早期预警评分(ViEWS)对急性冠脉综合征(ACS)患者发生心脏骤停的预测效能。方法选取发生心脏骤停的164例ACS患者为病例组,未发生心脏骤停的521例ACS患者为对照组。统计心脏骤停发生前24h各时间点ViEWS得分,比较其差异及变化趋势。结果病例组心脏骤停发生前24h、16h、8h、1h及30min ViEWS得分呈持续上升趋势,显著高于对照组 ...
刘培昌 +5 more
core
Progress in Clinical Application and Research Progress of Nicorandil [PDF]
, 2016 尼可地尔(Nicorandil)是第一个用于临床的具有硝酸酯类作用的离子通道开放剂,能够抑制Ca2+流入细胞以及促进K+的流出,从而促进血管平滑肌的舒张以及冠状动脉的扩张,因此在临床上将尼可地尔广泛用于治疗冠心病。尼可地尔能够改善稳定性及不稳定性心绞痛患者的生活质量,延长患者的生存时间。本文综合了国内外对尼可地尔的临床应用进行研究,对临床上使用尼可地尔治疗冠心病、保护心肌及改善预后具有指导意义。Nicorandil is a potassium channel opener with nitrate ...
魏香兰
core