P选择蛋白是一种在激活细胞表面表达的黏着分子,它能介导激活的上皮细胞或血小板与白细胞之间的反应。P选择蛋白在动脉粥样硬化斑处表达增加,在不稳定型心绞痛病人中也发现这种蛋白分子具有高血浆水平。P蛋白与组织发生血栓性炎症有明显的相关性[1]。因此我们推测大剂量的氯吡格雷也能有效减少血浆P蛋白的水平 ...
吴其明, 宋毓青
doaj
应用阿司匹林的ACS患者血清COX-2和TXA-2改变的临床意义研究
目的通过对服用阿司匹林的AMI、UAP、SAP患者和正常健康人血清中COX-2及TXA-2的浓度测定,探讨COX-2及TXA-2和服用阿司匹林的ACS的关系及其联合应用在应用阿司匹林的病人预防ACS出现的相关性临床研究。方法选择2004年10月到2009年2月在北华大学附属医院循环内科的住院患者74例。分为:急性心梗(AMI)组18例,不稳定型心绞痛(UAP)组33例,稳定型心绞痛(SAP)组25例,并设正常对照组36例。应用酶联免疫吸附法(ELISA)测定血清COX-2及TXA-2水平 ...
温玉新
doaj
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