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昭通市布鲁菌病流行特点及临床特征分析

open access: yesZhongguo shiyan zhenduanxue
目的探讨昭通市布鲁菌病(布病)患者的流行病学特征、临床表现及治疗转归,为当地布病防控及临床诊治提供参考依据。方法回顾性分析昭通市125例布病患者的人口学、流行病学资料、临床表现、血液学指标以及治疗转归情况。结果布病患者中男性占79.2%(99/125),女性占20.8%(26/125),92.7%的患者有明确接触史。最常见的发病年龄为30~69岁,占92%。主要临床症状为发热、骨关节痛、乏力、出汗,部分患者可出现寒战、肌痛、头痛、阴囊/睾丸痛、咳嗽、咳痰、腹痛等症状。50.4%的患者出现骨关节受累 ...
范怀艳   +5 more
doaj   +2 more sources

澳门地区产超广谱内酰胺酶大肠埃希菌基因型分析

open access: yesZhongshan Daxue xuebao. Yixue kexue ban, 2011
【目的】 了解澳门地区医院感染产超广谱β-内酰胺酶(ESBL)大肠埃希菌的临床分布特点和基因型特征。【方法】 收集2007年12月至2008年2月期间从澳门地区两家医院的临床患者中分离到的大肠埃希菌158株,用表型确定试验确定产ESBL大肠埃希菌。应用PCR方法分别扩增产酶菌株的CTX-M-3、CTX-M-9、TEM和SHV等常见的β-内酰胺酶基因,并结合临床分离菌株的分布特点对PCR扩增结果作进一步的分析。【结果】 澳门地区临床分离的158株大肠埃希菌中,有54株产ESBL,产酶率为34.2%。PCR
doaj   +1 more source

99m  Tc-NOET 心肌显像的临床初步研究

open access: yesZhongshan Daxue xuebao. Yixue kexue ban, 1999
目的:研究新型心肌灌注显像剂99mTc-NOET(N-乙氧基-N-乙基氨荒酸钠)的临床价值。方法:对 32 例冠心病 ( CHD)(其中冠脉造影 15例)、8例正常对照(其中冠脉造影 2 例)和 2 例扩张型心肌病患者进行99m Tc-NOET 心肌系列显像。结 果: 99mTc-NOET 运动心肌显像及再分布显像的适宜时间分别为 15 min和 2~ 4 h; 99m  Tc-NOET 有明显的再分布特征。 在本项研 究中, 99mTc-NOET 心肌显像诊断 CHD 的敏感性和特异性分别为 84.
doaj   +1 more source

WEABED-I—电子计算机辅助诊断和治疗临床水电解质和酸碱平衡紊乱

open access: yesZhongshan Daxue xuebao. Yixue kexue ban, 1988
WEABED—I电子计算机系统是为辅助诊断和治疗临床水、电解质和酸碱平衡紊乱而设计、编制的,分诊断主程序和治疗主程序二部分。诊断主程序利用简化的BAYES公式——评分法和智能分布建立数学模型而编写。可诊断临床常见各种水、电解质和酸碱平衡紊乱。治疗主程序综合现代国内外有关理论,原则,方法和公式,以指令和文本形式编写,根据病人所患紊乱综合症提出一个完整的治疗方案。临床应用150例结果表明:本系统的诊断和治疗水平基本达到本专业专家水平而高于一般临床医生。
陈国锐
doaj   +1 more source

类风湿关节炎不同滑膜淋巴细胞分布类型 的临床病理特点

open access: yesZhongshan Daxue xuebao. Yixue kexue ban, 2009
【目的】 探讨类风湿关节炎(RA)滑膜淋巴细胞分布与滑膜病理改变及临床病情活动性的关系。【方法】 细针滑膜活检获取48例活动期RA滑膜,连续切片HE及免疫组化染色观察淋巴细胞分布及病理改变,同时记录临床资料,对照组为骨关节炎14例和非炎性关节病16例。 【结果】 ① 48例RA滑膜根据衬里下层淋巴细胞分布特征分为生发中心(GC)型9例(18.8%)、聚集(Agg)型16例(33.3%)、弥漫型(Dif)型15例(31.2%)及无明显淋巴细胞浸润(Non)型8例(16.7%);②RA滑膜病理滑膜炎积分 ...
doaj   +1 more source

Combined detection of urinary biomarkers noninvasively predicts extent of renal injury in patients with early diabetic kidney disease with kidney qi deficiency syndrome: A retrospective investigation

open access: yesThe Anatomical Record, Volume 306, Issue 12, Page 2945-2957, December 2023., 2023
Abstract Incipient diagnosis and noninvasive forecasts using urinary biomarkers are important for preventing diabetic kidney disease (DKD) progression, but they are also controversial. Previous studies have shown a potential relationship between urinary tubular biomarkers (UTBs) and traditional Chinese medicine (TCM) syndrome in patients with DKD. Thus,
Wei Wu   +11 more
wiley   +1 more source

Trichophyton mentagrophytes complex: A retrospective study of 64 dogs from the Central United States (1997–2020)

open access: yesVeterinary Dermatology, Volume 34, Issue 4, Page 310-317, August 2023., 2023
Background – There are limited clinical studies evaluating the Trichophyton mentagrophytes complex, with most reports confined to small case studies. Additionally, the studies are dated and provide limited information on response to newer or currently available therapies.
Jason B. Pieper   +5 more
wiley   +1 more source

Transdermal drug delivery in horses: An in vitro comparison of skin structure and permeation of two model drugs at various anatomical sites

open access: yesVeterinary Dermatology, Volume 34, Issue 3, Page 235-245, June 2023., 2023
Background – Oral and parenteral drug delivery in horses can be difficult. Equine‐specific transdermal drug formulations offer improved ease of treatment; development of such formulations requires a deeper understanding of the structural and chemical tissue barrier of horse skin. Hypothesis/Objectives – To compare the structural composition and barrier
Samuel C. Bizley   +3 more
wiley   +1 more source

Development and validation of risk prediction models for large for gestational age infants using logistic regression and two machine learning algorithms 使用Logistic回归和两种机器学习算法开发和验证大于胎龄儿风险预测模型

open access: yesJournal of Diabetes, Volume 15, Issue 4, Page 338-348, April 2023., 2023
Highlights The logistic regression model consisted of seven commonly used clinical indicators (including lipid profile) and gestational diabetes mellitus subtypes, with an area under the curve (AUC) of 0.760 for the training set and 0.748 for the internal validation set.
Ning Wang   +11 more
wiley   +1 more source

Prevalence of type 1 and type 2 diabetes in children and adolescents in Germany from 2002 to 2020: A study based on electronic health record data from the DPV registry 2002~2020年德国儿童和青少年1型和2型糖尿病的患病率:一项基于来自DPV登记系统的电子健康记录数据的研究

open access: yesJournal of Diabetes, Volume 14, Issue 12, Page 840-850, December 2022., 2022
Highlights The prevalence rates of type 1 diabetes and type 2 diabetes in Germany are higher than estimated by the International Diabetes Federation (IDF). Since 2014, prevalence rates have increased only in 15–19‐year‐olds. Abstract Background To provide estimates of the nationwide prevalence of type 1 diabetes (T1D) and type 2 diabetes (T2D) in ...
Anna Stahl‐Pehe   +9 more
wiley   +1 more source

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