Whole genome analysis and molecular traceability of Pseudomonas aeruginosa in drinking water [PDF]
Objective: Provide data support for the source tracing and pollution prevention of Pseudomonas aeruginosa in drinking water in Hunan Province. Methods: According to the national food safety standards of GB 8538—2016, the bottled water was tested randomly
GAO Han +5 more
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Background – In clinical practice, the diagnosis of otitis externa (OE) normally is based on otoscopic examination and cytological findings, followed by empirical treatment with topic drugs. Biofilm‐producing bacteria are frequently present in OE, even if its presence is often underdiagnosed. Hypothesis/Objectives – The primary aim of this study was to
Luca Luciani +6 more
wiley +1 more source
Abstract Background Pseudomonas aeruginosa is the most commonly isolated bacterium from skin lesions of dogs with post‐grooming furunculosis (PGF). It is frequently found in human hair and skin care products, and may pose a health risk to consumers. Information regarding the prevalence of P. aeruginosa contamination of dog grooming products is lacking.
Elad Perry +5 more
wiley +1 more source
Background – Ceftazidime (CAZ) solutions are being used based on anecdotal reports for otitis externa complicated by multidrug‐resistant Pseudomonas aeruginosa (MDR PA). The chemical and microbiological stability of these proposed compounded solutions have not been evaluated, and likely are affected by the diluent and storage duration or temperature ...
Sarah E. Hoff +4 more
wiley +1 more source
Distribution of blood culture pathogens and clinical characteristics in children with acute leukemia complicated with septic shock [PDF]
Objective To explore the distribution of blood culture pathogens and clinical characteristics in children with acute leukemia complicated with septic shock.
Liu Tinghua, Lei Jiaying, Mai Yougang
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Development and evaluation of a real-time recombinase-aid amplification assay for rapid detection of Pseudomonas aeruginosa [PDF]
Objective To establish a real-time recombinase-aid amplification (RAA) method for rapid detection of Pseudomonas aeruginosa. Methods Specific primers and exo probes based on ecfX gene of P.
Jialin XIANG +8 more
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Analysis of global burden of bacterial infections: an interpretation of Global mortality associated with 33 bacterial pathogens in 2019 [PDF]
The Global Burden of Bacterial Infections report showed that in 2019, there were approximately 13.7 million deaths worldwide due to infection (95% UI ranging from 10.9 million to 17.1 million), and bacterial infection related deaths accounted for 13.6 ...
ZHANG Ying, JIANG Xiaofei
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Optimization of β lactam antibiotics regimens against bloodstream infection caused by Pseudomonas aeruginosa [PDF]
目的制定某院B内酰胺类在铜绿假单胞菌(PA)血流感染中的治疗方案。方法收集某院2015年至2016年血培养中铜绿假单胞菌共64株,测定B内酰胺类(哌拉西林/他唑巴坦,头孢他啶,头孢吡肟,亚胺培南,美罗培南)对铜绿假单胞菌的最低抑菌浓度(MIC)。用蒙特卡洛模拟计算多种治疗方案的达标率(PrA)和累积反应分数(CFR)。结果经验治疗时,哌拉西彬他唑巴坦4.5g(q6h),头孢他啶2g(q8h),头孢吡肟2g(q8h),亚胺培南1g(q6h),美罗培南1g(q8h,q6h),共6种方案的CFR值〉90 ...
于迪 +4 more
core +1 more source
Analysis of characteristics of infectious pathogens in malignant tumors combined with bloodstream infection and significance of serum glucose detection [PDF]
Background and purpose: The incidence rate of bloodstream infection (BSI) in patients with malignant tumor increases gradually with the progress of anti-tumor treatment. The treatment outcome is closely related to the infection of pathogen.
CHEN Zhujun, DING Zhimin, MA Xiaolu, WANG Yanchun, HU Haoyun, LU Renquan, GUO Lin
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抗生素发现\"黄金时代\"的结束以及日趋严重的抗生素耐药性问题给我们留下一个戏剧性的、缺乏新型药物来防治耐药病原体感染的难题。这使得从现有非抗生素药物中筛查抗菌活性药物成为一种新尝试。近期研究表明:美国食品药品监督管理局(FDA)批准的、本来用于治疗高血钙的药物硝酸镓具有良好的抗菌活性。不同于其他抗生素,镓的药理性质依靠化学拟态,它可以在目标酶分子中取代铁,从而干扰、扰乱细菌含铁蛋白的功能及细菌代谢,无论是在体外实验还是在体内实验中,镓对多种病原体,包括多重耐药病原体都表现出杀菌活性 ...
刘周 +6 more
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