用免疫组织化学桥联酶标APAAP法和PAP法对各型乙型肝炎113例检测了肝内的HLA-Ⅰ、Ⅱ类抗原、T细胞亚群、HBsAg和HBcAg,同时测定血清HBV DNA(斑点杂交)和β2微球蛋白(RIA)。结果表明;急性肝炎、慢性活动性肝炎、重症肝炎患者的肝细胞HLA-Ⅰ、Ⅱ类抗原表达增强,尤以Ⅰ类抗原明显,慢性迁延性肝炎则几乎无表达。肝细胞HLA-Ⅰ类抗原表达与肝内炎症反应、肝细胞膜型HBSAg和浆膜型HBcAg关系密切,肝内活动性病变主要浸润细胞为CD2+细胞,CD0+细胞构成主要的细胞亚群 ...
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[Icariside Ⅱ Inhibits Hepatitis B Virus and Modulates Mitochondrial Fission <i>in vitro</i>]. [PDF]
Liu Z +6 more
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[Altered oral microbiome and metabolites are associated with improved lipid metabolism in HBV-infected patients with metabolic dysfunction-associated fatty liver disease]. [PDF]
Zhang J +9 more
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[The consensus on the prophylaxis and treatment of HBV reactivation in B or plasma cell-directed CAR-T cell therapy(2021)]. [PDF]
Chinese Society of Lymphoma +3 more
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[Chronic HBV infection affects health-related quality of life in pregnant women in the second and third trimesters and postpartum period: a prospective cohort study]. [PDF]
Deng Y +8 more
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[Predictive Value of Baseline Serum Marker Levels for the Effect of Interferon Therapy in Patients With Chronic Hepatitis B]. [PDF]
Yan Y, Davgadorj C, Lyu C, Lu Z, Yu P.
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[The clinical characteristics and viral reactivation in B cell non-Hodgkin's lymphoma patients with hepatitis B virus infection]. [PDF]
Xu YQ +8 more
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提要83 例散发性慢性非甲乙丙丁戊型肝炎患者, 以逆转录聚合酶链反应检出庚型肝炎病 毒( H G v ) R N A 21 例( 25 . 3 % ) , 证实广州地区存在有慢性H G v 感染, H G v 感染是导致慢性病毒性 肝炎的病因之一。本研究证实H G V 感染可经非输血途径传播。 H G V 感染后所致的肝病, 临床表现 呈现多样性。 83 例散发性慢性非甲乙丙丁戊型肝炎患者中, 尚有62 例( 74 .
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[Risk assessment of hepatocellular carcinoma in patients with hepatitis B-related cirrhosis and hypertension: a propensity score matching-based retrospective cohort study]. [PDF]
Hu J, DU F, Ding L, Wang L, Zhao W.
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应用DNA电泳转移、生物素探针Southern杂交及不同探针重复杂交等3项新技术研究肝炎肝癌的肝内HBV DNA分子状态。经过方法学比较以电泳印迹取代毛细渗吸法对65例肝炎肝癌病人的101份肝内组织DNA进行尼龙膜快速转移和HBV DNA杂交,结果检出HBV DNA分子状态里整合型15份、游离型31份、整合型合并游离型30份。其中12例乙型肝炎标本为经生物素探针杂交检测,结果全部检出游离型HBV DNA。还有3例乙型肝炎标本和2例其它肝炎标本为经重复杂交检测 ...
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