Results 1 to 10 of about 29,393 (166)
, 2020 Plant phenomics is under rapid development in recent years, a research field that is progressing towards integration, scalability, multi-perceptivity and high-throughput analysis.
Guohui, Ding +6 more
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陕西地区静脉血栓栓塞症患者MTHFR和MTRR基因多态性分析以及对临床诊疗的指导意义
Zhongguo shiyan zhenduanxue, 2022 目的 探讨陕西地区静脉血栓栓塞症患者MTHFR和MTRR基因多态性分布情况。方法 选取西安交通大学第一附属医院静脉血栓栓塞症治疗患者439例，检测MTHFR和MTRR的基因型，统计基因型及等位基因分布特征，并对比国内外其他地区基因型及等位基因分布差异。结果 MTHFR和MTRR基因型分布CT、TT、CC;AA、AG、GG，分别占患者总数的48.06%、30.07%、21.87%;67.43%、28.93%、3.64%。MTHFR CC及TT等位基因频率分别为45.90%和54.10%;MTRR ...
张李婷, 马文兵, 关栋, 邓祥
doaj
Zhongguo shuxue zazhi, 2022 目的 探讨导致3例ABO血型正反定型不符的分子机制。方法 采用血型血清学方法对ABO正反定型不符标本进行亚型鉴定；采用PCR方法扩增ABO基因的6、7外显子；采用测序方法对ABO6、7外显子进行直接测序。结果 血型血清学试验结合基因测序证实3例标本为分别为：AwB(1例)、Ael(2例)。基因直接测序发现先证者1在A等位基因第7外显子发生了476C>T、595C>T突变，在B等位基因第7外显子526C>G、657C>T、703G>A、796C>A、803G>C、930G>A突变；先证者2 ...
Yishen LI, Yurong LI, Wenju ZHANG
doaj +1 more source
Regulation of Plasmodium yoelii Oocyst Development by Strain- and Stage-specific Small Subunit rRNA [PDF]
, 2015 疟疾是一种由疟原虫引起的，通过雌性按蚊作为媒介传播的全球性急性寄生虫病。疟原虫的一个独特的特点是在其生活史的不同发育阶段，有转录不同、结构发育期特异性的核糖体RNA（rRNA）起不同的作用；A型基因的转录主要在无性阶段，而S型基因主要在有性阶段或者是蚊期阶段特异表达。然而，至今还没有明确的功能性证据证明不同的rRNA在疟原虫发育的不同阶段能起到特异的作用。我们实验获得了一个具有卵囊发育缺陷表型的约氏疟原虫虫株，缺陷表型表现为卵囊发育较小、迟缓、并且不能发育为有感染力的子孢子 ...
齐艳伟
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Development of a novel fast immunoassay for HBV genotyping and study on the clinical significance of the quantitative hepatitis B core antibody level [PDF]
, 2015 乙型肝炎病毒（HepatitisBvirus,HBV）感染是一个严重的，世界范围内的公共卫生问题，可以导致肝炎，肝硬化（LC）和肝细胞癌（HCC），每年可以引起100万以上的人死亡。在HBV感染的临床诊断中，不同的HBV相关标志物指示了病毒产生，病毒多态性以及宿主免疫反应三个方面，从而全面了解HBV感染者的疾病状态，预测自然转归和治疗应答，监测疾病进展和治疗效果，对HBV感染者的管理和治疗起到关键的指导作用。目前在指示病毒产生的标志物方面，HBsAg，HBVDNA和HBeAg的检测手段相对成熟 ...
宋浏伟
core
Wildlife Letters, EarlyView.Climate change drives shifts in suitable habitats for Eurasian lynx and its prey (hare, roe deer) in Mohe, Daxing'anling Mountains. Under RCP scenarios, moderate warming (RCP4.5) promotes substantial habitat expansion, while high‐emission conditions (RCP8.5) lead to strong expansion in the 2050s but slower gains and partial contraction by the 2070s ...
Binglian Liu +5 more
wiley +1 more source
Association between Polymorphisms of ERCC1 and Response in Patients with Advanced Non-small Cell Lung Cancer Receiving Cisplatin-based Chemotherapy [PDF]
, 2010 Background and objective Results of studies on genetic polymorphisms of ERCC1 gene in DNA repair pathway which may affect response to platinum-based chemotherapy and survival in patients with non-small cell lung cancer are conflicting.
Hui ZHANG +6 more
core
Functional Ecology, EarlyView.Read the free Plain Language Summary for this article on the Journal blog. Abstract Root exudates play a key role as signals and nutrients in mediating plant–microbe communication. However, critical knowledge gaps remain regarding how root exudates mediate soil–microbe–plant interactions to regulate crop yield under long‐term straw mulching combined ...
Jiajie Song +7 more
wiley +1 more source
Association of the polymorphis ms in STIM1 / ORAI1 / TRPC1 genes with the risk of calcium u rolithiasis [PDF]
, 2015 目的：寻找基质相互作用因子1（Stromalinteractionmolecule1，STIM1）、钙释放激活钙通道调节分子1（Calciumrelease-activatedcalciummodulator1，ORAI1）和瞬时受体电位阳离子通道1（Transientreceptorpotentialcationchannel1，TRPC1）基因中与泌尿系含钙结石发病有关的易感位点及可能存在的单体型，探讨这三者基因多态性与泌尿系含钙结石发病的关联性。 方法：1、采用病例-对照研究策略 ...
林敬莱
core
Representation of obligate groundwater‐dwelling copepod diversity in European protected areas
Conservation Biology, EarlyView.Abstract Groundwaters sustain diverse surface ecosystems and are populated by metazoan species, mostly invertebrates, that provide fundamental ecological functions and are often of prominent conservation value due to narrow endemism and high phylogenetic rarity.
Francesco Cerasoli +7 more
wiley +1 more source