Optimization of beta lactam antibiotics regimens against bloodstream infection caused by Pseudomonas aeruginosa [PDF]
, 2017 目的制定某院beta内酰胺类在铜绿假单胞菌(PA)血流感染中的治疗方案。方法收集某院2015年至2016年血培养中铜绿假单胞菌共64株,测定; beta内酰胺类(哌拉西林/他唑巴坦,头孢他啶,头孢吡肟,亚胺培南,美罗培南)对铜绿假单胞菌的最低抑菌浓度(MIC)。用蒙特卡洛模拟计算多种治疗; 方案的达标率(PTA)和累积反应分数(CFR)。结果经验治疗时,哌拉西林/他唑巴坦4.5 g(q6 h),头孢他啶2 g(q8 h),头孢吡肟2; g(q8 h),亚胺培南1 g(q6 h),美罗培南1 g(q8 h,
于迪 +4 more
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血流感染的耐碳青霉烯类鲍曼不动杆菌的分子机制及临床研究 [PDF]
, 2018 目的探讨血流感染的耐碳青霉烯类鲍曼不动杆菌（CRAB）耐药机制,分析菌株同源性及患者的临床特征,为CRAB的感染控制提供实验依据。方法采用Bact/Alert 3D全自动血培养系统进行血培养,细菌鉴定和药敏使用Vitek-2 Compact全自动微生物分析系统。对2010年6月—2016年5月临床血流感染患者分离到的27株碳青霉烯类药物（亚胺培南和/或美罗培南MIC≥16μg/m L）耐药的CRAB复苏菌株,重新采用Vitek-MS质谱分析仪鉴定,采用改良Hodge试验检测碳青霉烯酶 ...
徐和平 +6 more
core +1 more source
Postoperative Application of Anti-infective Agents in 30 Patients Undergoing Stem Cell Transplantation in Our Hospital from 2003 to 2008 [PDF]
, 2010 目的:评价我院干细胞移植患者术后早期抗感染药的应用情况。方法:调查我院2003~2008年30例干细胞移植患者从预处理至术后早期抗感染药的应用情况,包括病原学检查、抗感染药费用、应用例/次、应用时间、用药频度(dddS)、药物利用指数(duI)及抗感染药联用情况,分析其应用合理性。结果:干细胞移植患者术后26例出现感染,感染率达86.67%,病原学检查阳性11例;抗感染药总费用327598.23元;术后早期使用频率列前10位的抗感染药中,duI1的3个;联合用药中,二联38例/次(占73.08 ...
欧阳华, 陈锦辉
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Infection status and etiological characteristics of diarrheogenic Escherichia coli among diarrhea patients in sentinel hospitals of Fujian Province in 2019 [PDF]
, 2020 Objective To investigate the infectious status, virulence gene, molecular typing and antibiotic resistance of diarrheogenic Escherichia coli (DEC) in sentinel hospitals of Fujian Province in 2019.
Haimei YE +4 more
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Monitoring and analysis of STEC in cow manure from a dairy farm and retail fresh beef around Chengdu City [PDF]
, 2023 ObjectiveTo understand the carrying status and strain characteristics of STEC strains in cattle and beef in the local area， provide scientific basis for evaluating the STEC pollution status， infection risk， prevention and control strategies in the region，
LEI Gaopeng +4 more
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, 2013 目的通过临床药师参与药物治疗实践,提高肾移植后肺部感染治疗的有效性、安全性与经济性。方法临床药师全程积极参与一例肾移植后肺部感染患者的治疗,在药物的选用、药物相互作用与不良反应的监护、患者出院宣教等方面提供药学服务。结果临床药师与医师紧密合作,患者治愈出院。结论临床药师积极参与肾移植后肺部感染患者的药物治疗,可提高药物治疗的有效性、安全性 ...
何乐 +4 more
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Analysis of virulence genes and antimicrobial resistance of Vibrio parahaemolyticus isolated from shellfish in 2018 [PDF]
, 2020 Objective To analyze the virulence genes and antimicrobial resistance of 140 Vibrio parahaemolyticus strains from shellfish collected from farms and markets.
Caiyun LIN +8 more
core +1 more source
Whole genome analysis and molecular traceability of Pseudomonas aeruginosa in drinking water [PDF]
, 2023 Objective: Provide data support for the source tracing and pollution prevention of Pseudomonas aeruginosa in drinking water in Hunan Province. Methods: According to the national food safety standards of GB 8538—2016, the bottled water was tested randomly
GAO Han +5 more
core +1 more source
Zhongguo shiyan zhenduanxue, 2011 目的分析耐亚胺培南铜绿假单胞菌对常用抗菌药物的耐药特征,并研究对亚胺培南的耐药机制。方法采用Micro-Walkaway-40进行细菌鉴定和药物敏感试验,应用PCR法对铜绿假单胞菌亚胺培南耐药相关基因（IMP、VIM、GIM、OXA）和膜微孔蛋白基因oprD2进行检测,琼脂稀释法检测氰氯苯腙（cccp）对耐亚胺培南铜绿假单胞菌MIC的影响。结果 65株耐亚胺培南铜绿假单胞菌对舒普深、特治星、阿米卡星的耐药率分别为38.5%、43.1%和44.6%,对头孢他啶、马斯平和环丙沙星的耐药率分别为50.8 ...
李杰, 苏维奇
doaj
, 2018 目的探讨儿童沙门菌感染的临床特点和耐药情况,为临床诊疗提供帮助。方法收集2013～2017年经粪便培养出沙门菌阳性的163例住院患儿的临床特征、沙门菌血清型分布情况及药敏试验结果,并进行回顾性分析。结果 163例沙门菌阳性患儿中,≤1岁患儿79例(48.5%);临床表现以发热、腹泻为主,体温>39℃达121例(74.2%),腹泻超过10次/d有52例(31.9%),且合并呼吸道感染多见,共56例(34.4%);沙门菌感染好发于夏秋季,5～10月共检出131例(80.4%)。血清分型以鼠伤寒沙门菌 ...
叶辉铭 +4 more
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