Results 11 to 20 of about 20,882 (170)
Highlights Lipid profiles of small extracellular vesicles (sEVs) in patients with diabetes or diabetic cardiovascular disease are rarely reported. n‐3 docosahexaenoic acid (DHA)‐enriched triacylglycerol (TG) was found to decrease in sEVs from serum of patients with diabetic cardiovascular disease (DM‐CAD).
Wei Ding +3 more
wiley +1 more source
Highlights Childhood obesity was significantly associated with the increased risk of insulin resistance (IR). There were 12 metabolites co‐associated with childhood obesity and IR, including seven amino acid and five fatty acid metabolites. The combination of body mass index standard deviation score and key metabolites could effectively predict the ...
Wu Yan +5 more
wiley +1 more source
Highlights Among 301 studies, diabetes mellitus was the most studied cardiometabolic risk factor. In the network meta‐analysis, cerebrovascular disease had the highest impact (relative risk [RR] 1.69; 95% CI, 1.65–1.73) on COVID‐19 outcomes compared to other cardiometabolic risk factors.
Alina Binbin Li +9 more
wiley +1 more source
Highlights We used data from the genome‐wide association studies database and two‐sample mendelian randomization method, we found that genetic evidence supporting that knee osteoarthritis is a potential risk factor for type 2 diabetes. Abstract Background Physical inactivity is an independent risk factor for type 2 diabetes (T2D).
Xing Xing +3 more
wiley +1 more source
Highlights Mild acquired impaired thyroid hormone sensitivity was widespread among the general populations. Reduced thyroid hormone sensitivity was related with metabolic syndrome and its components. Impaired thyroid hormone sensitivity might affect the distribution of adipose tissue and muscle.
Fang Lv +6 more
wiley +1 more source
Highlights Type 2 diabetes mellitus (T2DM) is characterized by progressive loss of beta‐cell function and mass. Numerous mechanisms of beta‐cell failure are involved. Preservation and/or enhancement of beta‐cell function is of great importance in delaying the progression of T2DM and the burden of its complications. Accurate evaluation of the effects of
Laure Sayyed Kassem +3 more
wiley +1 more source
Abstract This paper describes a method for investigating clinical process, Layered Analysis, which combines therapist countertransference reports and multi‐faceted microanalytic research approaches. Findings from the application of Layered Analysis to video‐recorded micro‐events of rupture and repair in four psychoanalytic parent–infant psychotherapy ...
Tessa Baradon +4 more
wiley +1 more source
目的比较食管鳞癌患者和健康志愿者的血清代谢谱,寻找食管鳞癌特有的代谢标志物。方法选择一组明确诊断的食管鳞癌患者作为实验组、一组健康志愿者作为对照组,以液相色谱-质谱法(LC-MS)检测其血清轮廓代谢谱,通过单变量分析和多变量(主成分分析及偏最小二乘回归分析法等)比较两组代谢谱并寻找差异性代谢物,通过代谢物质通路的富集分析探讨其可能异常生物学过程。结果入组食管鳞癌患者20例为实验组,健康对照20例为对照组,变异倍数分析和T检验等单因素分析结果得出21种差异性代谢物(P<0.05);选择单变量分析P ...
黄伟钊 +5 more
doaj
行为训练做一种丰容手段,在圈养野生动物管理中正逐渐运用。其目的是通过正强化刺激,让动物学会指令配合动物管理,从而减少胁迫。然而目前并没有合适的生理指标来评价训练对动物的影响。本实验对象是杭州动物园饲养的2只黑叶猴,通过对其中1只“大杭”个体进行持续30 d的正强化行为训练,训练目标为肌肉注射。通过GC-MS代谢组手段测定粪便所有代谢产物。模型显示,行为训练后大杭粪便代谢组与训练前具有显著的区别(PLS-DA:R2y=0.951,Q2=0.502;(O)PLS-DA:R2y=0.95,Q2=0.454 ...
何鑫, 王福云, 张秀秀, 朱岩
doaj
代谢综合征(MS)是一组以肥胖、高脂血症、糖尿病、高尿酸血症以及高血压等聚集发病的代谢紊乱症候群。随着人们生活方式改变,生活压力增大,以及不良饮食习惯的增加,代谢综合征的发病率逐渐升高。代谢综合征发病率的提高大大增加了其下游疾病,如动脉粥样硬化性心血管疾病、肝功能障碍等发生的风险,代谢综合征已成为威胁大众健康的严重公共卫生问题。随着对代谢综合征研究的不断深入,现已逐渐达成共识,认为代谢综合征发生的根本原因可能是慢性低度炎症反应[1]。
詹妮 +4 more
doaj

