Results 41 to 50 of about 20,998 (187)
Research on the effect of DHA on glucose metabolism in human lung cancer cells and its anti-tumor mechanism [PDF]
, 2015 研究背景及目的： 肺癌是人类最常见的恶性肿瘤之一，尽管近年来治疗取得了很大进展，治疗效果仍然较差。癌细胞具有偏向通过糖酵解方式来进行糖代谢获得能量的代谢特征使得肿瘤细胞能够比正常细胞具有更强的葡萄糖代谢能力，为肿瘤细胞的快速增殖与生长提供了能量来源，也使其具备更强的凋亡抵抗能力。天然产物凭借其来源广泛、类型多样、不良反应小，具有开发为化疗药物增效减毒辅助药物的潜力等特点备受关注。双氢青蒿素是青蒿叶中分离的有效抗疟成分，体内代谢活性产物为双氢青蒿素。药物学研究证实青蒿素类药物具有抗疟、抗血吸虫 ...
米彦军
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Functional Ecology, Volume 40, Issue 4, Page 800-815, April 2026.Read the free Plain Language Summary for this article on the Journal blog. Abstract Studies have shown that organisms may adjust metabolic rates in response to thermal variability, highlighting metabolic plasticity as a key adaptive mechanism. Understanding the extent of metabolic plasticity of an organism is key to predicting its adaptation to climate
Qian Hu +6 more
wiley +1 more source
中西医结合护理With the acceleration of global aging, the prevalence of diabetes among the elderly has been rising year by year. Physical activity, as an essential component of comprehensive diabetes management, plays a positive role in improving the health status of ...
HU Yixiang (胡怡香) +7 more
doaj +1 more source
Abnormal lipid metabolism in pterygium [PDF]
, 2015 研究背景：翼状胬肉作为一种常见的眼科疾病，其发病机理尚未明确，目前缺乏有效的药物治疗方法，手术切除是唯一有效的治疗方式。深入研究翼状胬肉的病理改变将有助于揭示翼状胬肉的病理生理过程，为发展新的治疗方法奠定基础。近年来，有研究发现翼状胬肉组织中存在异常脂类代谢，但是异常脂类代谢在翼状胬肉发生发展中的作用仍不清楚。 实验目的：检测翼状胬肉组织中的异常脂类代谢，探究脂类代谢异常在翼状胬肉发生发展过程中的作用。 实验方法：本实验收集35例翼状胬肉患者的病理组织和5例患者的正常结膜组织，用于冰冻包埋 ...
邹笃雷
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Advances in Elemene Nanodelivery Systems: From Material Design to Disease Treatment
Rare Metals, Volume 45, Issue 2, February 2026.ABSTRACT Elemene (ELE) is a bioactive sesquiterpenoid extracted from traditional Chinese herbs, demonstrating broad‐spectrum antitumor, anti‐inflammatory, and analgesic properties with significant therapeutic potential. However, its clinical utility is constrained by inherent physicochemical limitations, including volatility and hydrophobicity, which ...
Xiao Wang +9 more
wiley +1 more source
Lughawiyah: Journal of Arabic Education and Linguistics, 2019 Ϭ┘åϺ┘ê┘ä ┘çÏ░┘ç Ϻ┘ä┘à┘éϺ┘äÏ® ϺÏ│ϬϫϻϺ┘à Ϻ┘äϬ┘â┘å┘ê┘ä┘êϼ┘èϺ ┘âϺϬϼϺ┘ç Ϻ┘äÏ¡Ï»┘èϽ ┘äϬÏ╣┘ä┘è┘à Ϻ┘ä┘äÏ║Ï® Ϻ┘äÏ╣Ï▒Ï¿┘èÏ® ┘ü┘è Ï╣ÏÁÏ▒ 4.0. ┘è┘à┘â┘å ┘ä┘äÏÀ┘äϺϿ ϺÏ│ϬϫϻϺ┘à Ï¿Ï▒Ϻ┘àϼ ┘àϫϬ┘ä┘üÏ® Ï╣Ï¿Ï▒ Ϻ┘äÏÑ┘åϬÏ▒┘åϬ ϿϺÏ│ϬϫϻϺ┘à Ϻ┘äϡϺÏ│┘êÏ¿ Ïú┘ê Ϻ┘ä┘çϺϬ┘ü Ϻ┘äÏ░┘â┘è ┘ü┘è ┘â┘ä ┘à┘âϺ┘å ┘êÏ▓┘àϺ┘å Ï¿Ï│┘ç┘ê┘äÏ®.
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Functional Ecology, Volume 40, Issue 2, Page 534-552, February 2026.Read the free Plain Language Summary for this article on the Journal blog. Abstract Non‐structural carbohydrates (NSC) are critical mediators of plant adaptation to fluctuating light environments. They are tightly coordinated with plant economic strategy, that is, leaf economics spectrum (LES) and root economics spectrum (RES).
Lulu Xie +6 more
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浙江大学学报. 医学版睾丸支持细胞在精子发生过程中起重要作用。精子发生的异常与睾丸支持细胞糖脂代谢紊乱密切相关。睾丸支持细胞的代谢环境为缺氧，其主要的代谢方式包括糖酵解和脂肪酸β氧化，其中糖酵解是睾丸支持细胞为生精细胞提供能量的经典途径，而脂肪酸β氧化可能是睾丸支持细胞产生腺苷三磷酸的主要途径。目前睾丸支持细胞糖脂代谢与生精细胞发育的关系、糖代谢与脂代谢之间的联系尚不明确。包括性激素在内的多种激素可以通过调控内分泌影响睾丸支持细胞糖代谢。AMPK、mTOR ...
李 舒豪, 孔 亮, 梁 景岩, 马 坦
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Study on the mechanism of FBXW7 protects against insulin resistance via regulating FetuinA protein level [PDF]
, 2016 目的：FBXW7属于SCF类泛素连接酶E3，可调控脂质代谢关键转录因子和胰岛功能相关蛋白的泛素化降解。FetuinA是一类参与机体糖脂代谢调控的重要肝脏因子，与胰岛素抵抗发生密切相关，但在肥胖状态下肝脏中蛋白水平异常升高机制不得而知。本研究拟探究FBXW7在肥胖状态下对FetuinA蛋白水平调节机制，有助于进一步完善肥胖致胰岛素抵抗机制。 方法：本课题结合高脂饮食诱导的HFD肥胖小鼠模型和正常饮食诱导的ob/ob小鼠肥胖模型，检测小鼠糖脂代谢相关指标，采用Real-timePCR和ELISA ...
刘祺
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Optimization of mixed fermentation technology of Lactobacillus helveticus andLactobacillus rhamnosus based on high viable count [PDF]
, 2016 以瑞士乳杆菌和鼠李糖乳杆菌混合发酵培养,利用两菌株细胞代谢的差异,以静置发酵24 h后得到的活菌数目为指标,通过单因素实验和正交实验,研究了瑞士乳杆菌和鼠李糖乳杆菌高活菌数混合发酵的最适发酵条件。结果表明,瑞士乳杆菌和鼠李糖乳杆菌高活菌数混合发酵的最优条件为:发酵温度37℃,初始pH=6.8,接种量6%,瑞士乳杆菌:鼠李糖乳杆菌=1∶2,瑞士乳杆菌优先接种3 h。最终得到乳酸菌总活菌数为7.2×10~9m L~(-1)。与在相同条件下单独发酵的瑞士乳杆菌和鼠李糖乳杆菌活菌数相比,分别提高了1∶8倍和10.
李敬龙 +3 more
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