Results 51 to 60 of about 20,998 (187)
International Journal of Applied Linguistics, Volume 36, Issue 1, Page 714-724, February 2026.ABSTRACT Interlingual translation, as defined by Roman Jakobson, refers to the transfer of meaning between languages. However, this concept has often been conflated with linguistic shifts between distinct cultures and nation‐states. To challenge this misconception, I propose the concept of self‐consumption translation (SCT), a subfield of interlingual ...
Bilin (Belen) Liu
wiley +1 more source
The Regulation of Transforming Growth Factor β Signaling Activity by Nuclear Receptor Nur77 [PDF]
, 2015 孤儿核受体Nur77是核受体（NuclearReceptors，NRs）超家族中非常重要的一员。它作为细胞内立早基因的产物，能够响应包括各类生长因子在内的多种刺激。同时，Nur77广泛参与到机体的生理以及病理学过程中，如：糖脂代谢，细胞自噬，炎症发生发展以及肿瘤的生长凋亡等过程。转化生长因子（TransformingGrowthFactorβ，TGF-β）信号通路在体内广泛参与包括糖代谢，脂质代谢，胞外基质的更替，细胞的增殖、分化，组织的纤维化以及肿瘤的发生发展等多种生理以及病理过程的调控。对TGF ...
林佳城
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Integrative Conservation, Volume 4, Issue 4, Page 675-685, December 2025.We demonstrated that Anguilla japonica eDNA concentration was allometrically scaled with their body size in both the laboratory and riverine environments. Integrating body size allometry has the potential to improve population abundance estimates in the field, whereas further clarification is required for understanding eDNA production mechanisms ...
Toshiaki S. Jo +2 more
wiley +1 more source
Zhongguo shiyan zhenduanxue, 2021 的身心健康[1]。充足的睡眠对正常的生长发育、代谢和免疫等至关重要。实验和流行病学研究均表明,睡眠时间和（或）质量的下降,尤其是阻塞性睡眠呼吸暂停（OSA）等睡眠障碍是心血管代谢异常的危险因素[2-4]。以胰岛素抵抗、高血脂、肥胖、冠心病等为主的心血管代谢性疾病患病率不断上升;而睡眠新近被认为是心血管代谢风险的预测因子[5]。本文综述了睡眠与心血管代谢性疾病的相关研究进展。1睡眠对糖代谢的影响睡眠不足和（或）睡眠障碍增加糖尿病发病风险。一项报告[6]称,0 ...
曾繁杰, 杨宝霞, 黎萍
doaj
The diversity and physiological characteristics of microbes involved in hydrogen metabolism from deep-sea hydrothermal vent fields [PDF]
, 2015 由微生物介导的发酵产氢由于具有众多的优点，在制氢方面可能具有更大的生产潜力。深海热液系统具有特殊生态环境,与陆地和海洋中的其他生物群落有着根本的区别。本研究针对深海热液环境开展氢代谢菌的研究工作,以期获得特殊生境中的氢代谢微生物资源和氢酶资源。 利用西南印度洋，南大西洋，东太平洋等不同来源的深海热液环境样品，进行了氢代谢菌的分离培养工作。共获得7个高温发酵产氢富集培养物。细菌16SrRNA基因序列分析表明，富集培养物中的主要类群是Calroanaerobacter，Clostridium ...
姜丽晶
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Integrative Conservation, Volume 4, Issue 4, Page 652-664, December 2025.We profiled nutritional and physiological markers in captive sifakas, endangered primates from Madagascar, managed in expansive, non‐native forest enclosures. Variation in many markers reflects freely foraged diets and the energy required to maintain homeostasis under more naturalistic conditions.
Lydia K. Greene +5 more
wiley +1 more source
The scale-up fermentation of DAM and preliminary study of DAM-induced apoptosis in HeLa cells [PDF]
, 2015 丰富的海洋生物资源为天然产物提供了重要来源，红树内生真菌由于独特的生理和代谢系统，产生了一些新颖独特的次级代谢产物。去乙酰真菌环氧二烯（Deacetylmycoepoxydiene，DAM）是本课题组杨丽珊同学从红树植物秋茄内生拟茎点霉属真菌A-1-2-3次级代谢产物中分离得到，具有新颖的含氧桥结构骨架，前期实验表明，该化合物具有较强的抗肿瘤活性。 本论文通过对菌株发酵技术参数的优化，确立了DAM液体发酵放大的工艺控制流程并进行了规模制备，初步阐明了DAM的抗肿瘤作用及其诱导HeLa细胞凋亡的作用机制 ...
林鹏
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Integrative Conservation, Volume 4, Issue 3, Page 362-380, September 2025.Occurrences of dust storms and long‐distance movement of dust across landscapes is constantly increasing in south Asia. This dust is expected to have profound impact on vegetation health and sustainability as dust may contribute to nutrient budgets of the forest ecosystems, while it could impart various stresses to the plants.
Shree P. Pandey +2 more
wiley +1 more source
Zhongguo cuzhong zazhi代谢性脑血管病是一个新近提出的概念，指由传统代谢危险因素和残余代谢危险因素引起的脑血管损害，通过干预代谢危险因素可有效改善其预后的一种临床综合征。代谢途径并非独立存在，脑、心脏、肝脏、肾脏和肠道等多个器官的各种代谢途径相互影响、共同作用、交织成网，构成了人体的代谢网络，而代谢网络的异常导致了代谢性脑血管病的发生。同时，代谢危险因素的存在可同时造成多个靶器官损害，且神经系统与心血管系统、内分泌系统、消化系统等可通过多种病理生理过程相互影响。因此 ...
许杰, 王拥军 XU Jie, WANG Yongjun
doaj +1 more source
Structure and function research of the nuclear receptor PPARγ and its novel selective regulator [PDF]
, 2016 过氧化物酶体增殖剂激活受体家族(PPARs)是一类配体依赖型的激活因子，它们是核受体超家族中的重要成员。PPARs是机体调节新陈代谢平衡的关键转录因子，因此PPARs也成为了研发治疗糖尿病，心血管疾病等代谢相关疾病药物的热门分子靶标。 糖尿病是困扰现代人健康的一组常见代谢性疾病，但是目前临床上仍然缺乏安全且有效的糖尿病治疗药物。噻唑烷二酮（Thiazolidinedione，TZD)类药物是经典的PPARγ完全激动剂，由于它能够改善由糖尿病引起的胰岛素耐受等症状，目前已经运用于临床治疗Ⅱ型糖尿病 ...
邱琳
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