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浙江大学学报. 医学版皮肤纤维化主要是指成纤维细胞过度增殖和细胞外基质过度沉积这一过程，会导致增生性瘢痕、瘢痕疙瘩、系统性硬化病等疾病。皮肤纤维化是一个动态变化的复杂过程，各种皮肤常驻细胞以及炎症细胞互相作用，最终导致细胞外基质沉积，甚至呈现侵袭性生长特征。细胞的表型及其功能的实现依赖于动态的细胞代谢反应，而细胞信号转导又与细胞代谢密切偶联。由于皮肤纤维化微环境中的细胞代谢-信号偶联对于炎症反应和纤维化活化至关重要，调节这些代谢途径可以为抑制甚至逆转皮肤纤维化进展的治疗提供新视角。本文系统回顾了皮肤纤维化中各类细胞的代谢特征，
钱 姝桐 +3 more
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Zhongshan Daxue xuebao. Yixue kexue ban, 2021 目的比较食管鳞癌患者和健康志愿者的血清代谢谱，寻找食管鳞癌特有的代谢标志物。方法选择一组明确诊断的食管鳞癌患者作为实验组、一组健康志愿者作为对照组，以液相色谱-质谱法（LC-MS）检测其血清轮廓代谢谱，通过单变量分析和多变量（主成分分析及偏最小二乘回归分析法等）比较两组代谢谱并寻找差异性代谢物，通过代谢物质通路的富集分析探讨其可能异常生物学过程。结果入组食管鳞癌患者20例为实验组，健康对照20例为对照组，变异倍数分析和T检验等单因素分析结果得出21种差异性代谢物（P<0.05）；选择单变量分析P ...
黄伟钊 +5 more
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代谢组学在代谢性脑血管病中的应用研究 Application of Metabolomics in Cerebro-Metabolic Disease
Zhongguo cuzhong zazhi脑血管病是全球范围内导致人类死亡和残疾的主要原因，其中很高比例与代谢紊乱相关。代谢性脑血管病是指由传统代谢危险因素和残余代谢危险因素导致的脑血管损害，以血管结构受损及功能障碍为主要病理生理学表现，干预代谢危险因素可有效改善预后的一种临床综合征。代谢组学是采用高通量组学技术对所有代谢物进行鉴定和定量的手段，是未来研究代谢性脑血管病的重要抓手。本文总结了代谢组学、脂质组学在代谢性心脑血管疾病方面的研究，旨在为代谢性脑血管病的代谢组学研究开展及其临床防治提供参考。 Abstract ...
钟文华1，薛婧2，许杰1，2 ( ZHONG Wenhua1, XUE Jing2, XU Jie1,2 )
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中西医结合护理, 2022 Objective To investigate the effect of multidisciplinary team management by using the PDCA approach in blood glucose control of elderly patients with type 2 diabetes in the non-endocrinology department.
FAN Meihong (樊美红) +1 more
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Progress of clinical observation and nursing of patients with pituitary apoplexy (垂体危象患者的临床观察与护理进展)
中西医结合护理, 2022 Given the complex of clinical classification in pituitary apoplexy, it is required to carry out detailed observation, timely treatment and comprehensive nursing for patients with pituitary apoplexy. This paper reviewed studies of clinical observation and
LIANG Qian (梁倩) +1 more
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Lughawiyah: Journal of Arabic Education and Linguistics, 2023 This article aims to analyze the beautiful verses of As─ülib Bal─üghiyyah┬á and its meaning in Surah Al-Fath, because Surah Al-Fath has Uslub which contains secrets and wisdom of the victory of Muslims, the forgiveness of Allah S.W.T, as well as the events of B─üiÔÇÖu Ridw─ün and Shulhu-l-Hudaibiyyah, by using very beautiful languages and has a high m ...
Fairuz Subakir Ahmad +3 more
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Application Progress of Omics Technology in Monascus sp. Research(组学技术在红曲霉研究中应用的进展) [PDF]
Shipin kexue jishu xuebao, 2023 The development of omics technologies (OTs) has expanded our understanding of growth and development, synthesis of metabolites, and the mechanisms of metabolic regulation in Monascus sp..
WANG Changlu(王昌禄) +4 more
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Lughawiyah: Journal of Arabic Education and Linguistics, 2021 Online learning is a learning via internet without meeting face-to-face between teachers and students. This online learning system is relatively new, therefore teachers and students should adapt quickly. This study aims to determine the online Arabic learning system during the COVID-19 pandemic at Madrasah Tsanawiyah Negeri (MTsN) 1 Surakarta ...
Yuliana Prativi, Muhammad Zaenuri
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Lughawiyah: Journal of Arabic Education and Linguistics, 2021 This study aims to determine the development of Arabic semantics in Diwan Abi Tammam book. Abu Tammam is a modern Arabic poet. He has poetry books which have been printed several times and all of his poetry is collected in a book that is known as Diwan Abi Tammam. This research is limited to the types of semantic development.
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