Results 91 to 100 of about 5,828 (148)

低分子量肝素治疗的临床实验监测

Zhongguo shiyan zhenduanxue, 2003
目的　进一步探讨活化的部分凝血活酶时间 （APTT）对低分子量肝素 （LMWH）治疗的实验监测价值。方法　对LMWH治疗前及治疗后的 2 6 2份血浆标本进行了APTT和抗 Ⅹa的测定 ,观察不同抗 Ⅹa活性水平的LMWH对APTT的影响。结果　当LMWH的抗 Ⅹa活性在 0 .8～ 1.2U/ml时 ,APTT中度延长 ,当LMWH的抗 Ⅹa活性大于 1.2U/ml时 ,APTT明显延长。结论　当使用治疗剂量的LMWH ,特别是剂量≥ 1mg/kg体重时 ...
刘贵建, 王静, 张永宏, 赵淑芳, 刘锦丽   +4 more
doaj  

细胞色素C及相关细胞凋亡蛋白、基因在原发性肝癌组织表达的临床意义

Zhongguo shiyan zhenduanxue, 2011
目的观察外源性凋亡通路中Caspase8和Bid及内源性凋亡通路中Bcl-2、Bax、细胞色素C（Cyt-C）和Cas-pase9在50例原发性肝细胞癌（肝癌组）及30例正常肝组织（对照组）中的表达,并分析其与病理分期、肿瘤分化程度和淋巴结转移的关系。方法应用免疫组织化学方法检测Bax表达,应用核酸原位分子杂交方法检测Caspase8、Bid、Bcl-2、Cyt-C和Caspase9表达。结果 Caspase8表达强度与对照组比较呈升高趋势（P0.05）。Bid阳性表达率与对照组比较呈下降趋势（P0 ...
陈昊, 陈乃玲, 张春芳, 张昶, 王红霞, 赵文海   +5 more
doaj  

[<i>Jiangzhi Quban</i> Recipe improves type 2 diabetes mellitus complicated with hyperlipidemia by multi-target regulation of the inflammation-metabolism network: network pharmacology analysis and clinical validation]. [PDF]

Nan Fang Yi Ke Da Xue Xue Bao
Li Z, Zhou F, Sun X, Zhao H, Jin Y, He P, Jia Y.   +6 more
europepmc   +1 more source

[ERI3 expression is elevated in hepatocellular carcinoma and correlates with poor patient prognosis]. [PDF]

Nan Fang Yi Ke Da Xue Xue Bao
Zhao X, Wang H, Song Y, Yuan S, Zhang Z, Zhou X, Li S, Li X, Li F.   +8 more
europepmc   +1 more source

LncRNA OIP5-AS1调节miR-186a-5p促进肝细胞癌凋亡及糖酵解

Zhongguo shiyan zhenduanxue
目的 探讨lncRNA OIP5-AS1在肝细胞癌(HCC)中的表达及其对肿瘤发展的影响，并揭示其潜在的分子机制。方法 采用实时荧光定量PCR(RT-qPCR)分别检测LncRNA OIP5-AS1和miR-186a-5p在肝癌组织、癌旁组织的表达以及肝癌细胞系HepG2、Hep3B、Huh-7和正常肝细胞系LO2中的表达情况。Pearson相关分析评估LncRNA OIP5-AS1与miR-186a-5p表达水平的相关性。双荧光素酶报告实验检测LncRNA OIP5-AS1与miR-186a ...
臧书宁, 杨正波, 吴惧
doaj  

[EVA1A overexpression improves non-alcoholic fatty liver disease in mice by regulating lipid metabolism and promoting lipophagy]. [PDF]

Nan Fang Yi Ke Da Xue Xue Bao
Xu J, Yang D, Zang K, Chu M, Zhao Q, Li Q, Lu S, Chen X, Li N.   +8 more
europepmc   +1 more source

[Impact of aspirin use on pregnancy outcomes in patients with systemic lupus erythematosus]. [PDF]

Beijing Da Xue Xue Bao Yi Xue Ban
Li X, Zhao J, Mu R.
europepmc   +1 more source

鞍上肿瘤伽玛刀术后下丘脑综合征1例分析 [PDF]

, 2007
董闽田
core  

[Gandou Bushen decoction ameliorates ovarian injury in murine hepatolenticular degeneration via the AGE/RAGE/NF-κB signaling pathway]. [PDF]

Zhejiang Da Xue Xue Bao Yi Xue Ban
Jiang P, Wu L, Han H.
europepmc   +1 more source

[Research progress on toxic shock syndrome due to group A <i>Streptococcus</i> infection in children]. [PDF]

Zhongguo Dang Dai Er Ke Za Zhi
Wang HY, Zhou W, Huang LS.
europepmc   +1 more source