EGCG对人肝癌细胞株HepG2裸鼠移植瘤COX-2、VEGF和bFGF表达的调控
探讨表没食子儿茶素没食子酸脂EGCG对人肝癌细胞株HepG2裸鼠移植瘤生长和肿瘤血管生成的抑制作用及EGCG对移植瘤环氧合酶-2(COX-2)?血管内皮生长因子(VEGF)和碱性成纤维生长因子(bFGF)表达的调控?【方法】 将肝癌细胞HepG2种植至裸鼠背部皮下,10 d后开始用不同浓度EGCG治疗,38 d后处死?观测裸鼠移植瘤的体积和质量?并采用间接免疫流式细胞术和Western Blot法检测移植瘤COX-2?VEGF和bFGF的表达,用免疫组化法检测微血管密度(MVD)?【结果 ...
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[Exercise-induced hyperinsulinism: genetic basis and clinical management]. [PDF]
Zhang QT, Hou L.
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[Angio-associated migratory cell protein is highly expressed in hepatocellular carcinoma and promotes tumor cell invasion and metastasis]. [PDF]
Li C, Yin G, Cheng X, Jiang Y.
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摘 要: 【目的】 评价生物素化CD45单抗介导的99mTc-生物素在人Raji细胞移植瘤裸鼠模型中三步法预定位放免显像的价值。【方法】 CD45单抗及DTPA-生物素的99mTc标记采用直接标记法。取人Raji细胞移植瘤裸鼠18只,随机分为2组,每组9只。实验组为三步法预定位放免显像组,静注生物素化CD45单抗100 μg,48 h后静注亲和素200 μg,再过48 h静注99mTc-生物素7.4 MBq(20 μg);对照组为99mTc-CD45单抗放免显像组,静注99mTc-CD45单抗100 ...
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[<i>Hugan</i> Decoction alleviates non-alcoholic fatty liver disease in rats by activating the AMPK/m-TOR signaling pathway and reducing lipid synthesis]. [PDF]
Shang D, Li W, Cui L, Chen M.
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[Knockdown of <i>Cav1</i> inhibits mitochondrial function and mRNA m<sup>6</sup>A modification and expression of key genes in mouse hepatocytes]. [PDF]
Ding S +4 more
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[Extracellular matrix materials and tissue regeneration and repair]. [PDF]
Zhao L, Xie H.
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[Clinical and genetic characteristics of 14 children with sodium taurocholate co-transporting polypeptide deficiency]. [PDF]
Ma RX +7 more
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[Performance evaluation of different filtration fractions during daytime continuous renal replacement therapy]. [PDF]
Wang L, Chen Y, Xu G, Xu C.
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[Puerarin alleviates rheumatoid arthritis in rats by modulating TAK1-mediated TLR4/NF-κB signaling pathway]. [PDF]
Xu M +9 more
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