Results 11 to 20 of about 12,687 (169)

Rationale and design for the Blood Pressure Control Target in Diabetes (BPROAD) study 糖尿病血压控制目标(BPROAD)研究的原理和设计

Journal of Diabetes, Volume 15, Issue 12, Page 1029-1040, December 2023., 2023
Highlights The Blood Pressure Control Target in Diabetes (BPROAD) study is a multicenter, randomized controlled trial conducted in mainland China to test the hypothesis of whether intensive blood pressure (BP) management (systolic BP <120 mm Hg) has additional benefits over standard BP management (systolic BP <140 mm Hg) over a follow‐up period of up ...
The BPROAD Study Group, Guang Ning, Jiang He, Weiqing Wang, Yufang Bi, Dalong Zhu, Jiguang Wang, Shengdi Chen, Yu Xu, BPROAD coordinating team at Ruijin Hospital, Lawrence J. Appel, William C. Cushman, Vivian A. Fonseca, Jeff D. Williamson, David M. Reboussin, Yaling Han, Hongbing Shen, Minghui Zhao, Hui Wang   +18 more
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Blood pressure targets for prevention of cognitive decline in patients with diabetes and hypertension: Design of the Blood Pressure Control Target in Diabetes (BPROAD) Cognitive Study 高血压目标对于预防糖尿病和高血压患者的认知下降:BPROAD认知研究的设计

Journal of Diabetes, Volume 15, Issue 12, Page 1041-1047, December 2023., 2023
Highlights The optimal blood pressure (BP) target in patients with type 2 diabetes mellitus (T2DM) for the management of cognitive decline remains unknown. The Blood Pressure Control Target in Diabetes (BPROAD) Cognitive Study was designed to determine whether intensive BP treatment (systolic BP <120 mm Hg) reduces risk of dementia and mild cognitive ...
The BPROAD Study Group, Guang Ning, Jiang He, Weiqing Wang, Yufang Bi, Dalong Zhu, Jiguang Wang, Shengdi Chen, Yu Xu, BPROAD coordinating team at Ruijin Hospital, Lawrence J. Appel, William C. Cushman, Vivian A. Fonseca, Jeff D. Williamson, David M. Reboussin, Yaling Han, Hongbing Shen, Minghui Zhao, Hui Wang   +18 more
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Decreased in n‐3 DHA enriched triacylglycerol in small extracellular vesicles of diabetic patients with cardiac dysfunction 糖尿病合并心脏功能障碍患者细胞外小囊泡中n‐3 DHA 富集的三酰甘油减少

Journal of Diabetes, Volume 15, Issue 12, Page 1070-1080, December 2023., 2023
Highlights Lipid profiles of small extracellular vesicles (sEVs) in patients with diabetes or diabetic cardiovascular disease are rarely reported. n‐3 docosahexaenoic acid (DHA)‐enriched triacylglycerol (TG) was found to decrease in sEVs from serum of patients with diabetic cardiovascular disease (DM‐CAD).
Wei Ding, Xuejuan Zhang, Dandan Xiao, Wenguang Chang   +3 more
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Fatty acid β‐oxidation and mitochondrial fusion are involved in cardiac microvascular endothelial cell protection induced by glucagon receptor antagonism in diabetic mice 脂肪酸β‐氧化和线粒体融合参与胰高血糖素受体拮抗剂对糖尿病小鼠心脏微血管内皮细胞的保护作用

Journal of Diabetes, Volume 15, Issue 12, Page 1081-1094, December 2023., 2023
Highlights Glucagon receptor (GCGR) monoclonal antibody (mAb) improves cardiac function and attenuates microvascular damage in db/db mice. GCGR mAb ameliorates the oxidative stress of cardiac microvascular endothelial cells in diabetic mice. GCGR mAb counteracts the diabetes‐induced upregulation of carnitine palmitoyltransferase 1B, optic atrophy type ...
Peng Wang, Rui Wei, Xiaona Cui, Zongzhe Jiang, Jin Yang, Lingyun Zu, Tianpei Hong   +6 more
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A network meta‐analysis of association between cardiometabolic risk factors and COVID‐19 outcome severity 心血管代谢危险因素与COVID‐19严重程度关联的网络荟萃分析

Journal of Diabetes, Volume 15, Issue 11, Page 968-977, November 2023., 2023
Highlights Among 301 studies, diabetes mellitus was the most studied cardiometabolic risk factor. In the network meta‐analysis, cerebrovascular disease had the highest impact (relative risk [RR] 1.69; 95% CI, 1.65–1.73) on COVID‐19 outcomes compared to other cardiometabolic risk factors.
Alina Binbin Li, Bo Yang, Yufei Li, Rachel Huynh, Samuel Shim, Kenneth Lo, Jie Li, Andrew Zullo, Wen‐Chih Wu, Simin Liu   +9 more
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Effect of dipeptidyl peptidase‐4 inhibitor on the progression of coronary artery disease evaluated by computed tomography in patients receiving insulin therapy for type 2 diabetes mellitus DPP‐4抑制剂对接受胰岛素治疗的2型糖尿病患者冠状动脉疾病进展的影响

Journal of Diabetes, Volume 15, Issue 11, Page 944-954, November 2023., 2023
Highlights Preclinical data showed that dipeptidyl peptidase‐4 inhibitors (DPP‐4is) may prevent insulin‐induced atherosclerosis. In patients treated with insulin for type 2 diabetes who underwent ≥2 serial coronary computed tomography angiographies(CCTA), a new obstructive coronary artery disease (OCAD) was less developed on the follow‐up CCTA in those
Young Choi, Seung‐Hyun Ko, Kiyuk Chang, Ki Dong Yoo, Sang‐Hyun Ihm   +4 more
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Exosomal miR‐let‐7c‐5p is involved in the cognitive function of type 2 diabetes mellitus patients by interleukin 10: A cross‐sectional study 外泌体miR‐let‐7c‐5p通过白细胞介素10参与2型糖尿病患者的认知功能:一项横断面研究

Journal of Diabetes, Volume 15, Issue 11, Page 978-986, November 2023., 2023
Highlights Both interleukin‐10 levels and exosomal miR‐let‐7c‐5p levels are correlated with cognitive function in patients with type 2 diabetes mellitus. There is a negative association between interleukin‐10 levels and exosomal miR‐let‐7c‐5p levels in the plasma of patients with type 2 diabetes mellitus. Abstract Background Interleukin (IL)‐10 plays a
Hui Zhang, Shufang Yang, Wenwen Zhu, Tong Niu, Jue Wang, Mingyue Yang, Enlin Liu, Jumei Wang, Sumei Li, Haoqiang Zhang   +9 more
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Associations of blood biomarkers with arterial stiffness in patients with diabetes mellitus: A population‐based study 糖尿病患者血液生物标志物与动脉硬化的关系: 一项基于人群的研究

Journal of Diabetes, Volume 15, Issue 10, Page 853-865, October 2023., 2023
Highlights Few studies have investigated the association of large‐scale biomarkers and pulse wave velocity (PWV) among diabetic patients. This study investigates the relationships of serum laboratory tests with PWV and explored the associations between PWV and all‐cause mortality among diabetic patients.
Yong‐Qi Liang, Rui Zhou, Hao‐Wen Chen, Bi‐Fei Cao, Wei‐Dong Fan, Kuan Liu, Qi Zhong, Yi‐Ning Huang, Xian‐Bo Wu, Meng‐Chen Zou   +9 more
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The serum creatinine to cystatin C to waist circumference ratios predicts risk for type 2 diabetes: A Chinese cohort study 血清肌酐/胱抑素C与腰围比例预测2型糖尿病的风险: 一项中国队列研究

Journal of Diabetes, Volume 15, Issue 10, Page 808-816, October 2023., 2023
Highlights Higher creatinine to cystatin C to waist circumference ratio (CCR/WC ratio) was associated with decreased risk of type 2 diabetes mellitus (T2DM) among Chinese people. A nonlinear association was found between CCR/WC and T2DM risk. Abstract Background There is a lack of research regarding the relationship between creatinine to cystatin C to ...
Yinfei Chen, Weiheng Wen, Zhiliang Mai, Ming Wang, Hong Chen, Jia Sun   +5 more
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Association between serum LDL‐C concentrations and risk of diabetes: A prospective cohort study 血清低密度脂蛋白胆固醇浓度与糖尿病风险之间的关联: 一项前瞻性队列研究

Journal of Diabetes, Volume 15, Issue 10, Page 881-889, October 2023., 2023
Highlights Serum low‐density lipoprotein cholesterol (LDL‐C) levels were positively and significantly associated with a high risk of incident diabetes. Even in participants with normal LDL‐C levels (<130 mg/dL), a 1‐SD increase in LDL‐C levels was significantly associated with a higher risk of diabetes development.
Jiaojiao Huang, Hong Lin, Shuangyuan Wang, Mian Li, Tiange Wang, Zhiyun Zhao, Yu Xu, Min Xu, Jieli Lu, Yuhong Chen, Guang Ning, Weiqing Wang, Yufang Bi, Long Wang   +13 more
wiley   +1 more source