Results 1 to 10 of about 9,176 (119)

糖尿病酮症酸中毒合并心衰及糖尿病大疱病1例

Zhongguo shiyan zhenduanxue, 2021
糖尿病大疱病是一种少见的糖尿病并发症,发病率为0.16%-0.5%[1-2],发病时皮肤水疱突然形成,可自行消退,一般在2-5周愈合,不遗留疤痕或萎缩,常有反复发作病史,多合并有糖尿病周围神经病变[3-4]、大血管病变[5]、微血管病和血糖控制不佳[6],以及钙,镁代谢紊乱等。目前糖尿病酮症酸中毒合并心衰是否能够诱发糖尿病大疱病,或是该状态下快速补液能否诱发糖尿病大疱病尚不明确。本文报道1例糖尿病酮症酸中毒(DKA)合并心衰及糖尿病大疱病的患者,探讨该状态下诱发糖尿病大疱病的可能因素。
乔月, 李阳阳, 程妍, 王丽娟, 杨茂光, 刘琳, 蔡寒青, 张秀娟   +7 more
doaj  

MiRNA在糖尿病心肌病中的研究进展

Zhongguo shiyan zhenduanxue, 2020
糖尿病心肌病(DCM)会加速心肌细胞凋亡,使心肌细胞收缩机制发生异常改变以及发生心力衰竭等。根据国际糖尿病联合会的数据,2013年全球糖尿病患者有3亿8 200万人,预计到2035年将上升至5亿9 200万人[1]。作为临床上最常见的疾病之一,糖尿病晚期可能会出现糖尿病神经病变、糖尿病肾病、糖尿病心肌病等多种并发症,而糖尿病心肌病则是全球糖尿病人群致死的主要原因之一[2]。目前糖尿病心肌病的治疗方法多以口服降糖药物 ...
谭林琳, 吴箴言, 马光朋, 费运微, 王智慧   +4 more
doaj  

Taiwanese consensus statement on the use of diabetes‐specific formula: Scientific evidence

Journal of Diabetes Investigation, Volume 17, Issue 8, Page 1442-1450, August 2026.
ABSTRACT Introduction Medical Nutrition Therapy remains the cornerstone of diabetes management. Clinical evidence shows that early intervention with medical nutrition therapy can significantly improve cardiometabolic markers, thereby delaying or preventing diabetes‐related complications.
Chih‐Hsun Chu, Hui‐Yu Peng, Chun‐Chuan Lee, Chih‐Yuan Wang, Yuh‐Jane Ko, Wen‐Hui Chen, Pi‐Hui Hsu, Chien‐Ning Huang, Yi‐Sun Yang, Kuei‐Mei Yeh, Chung‐Mei Ouyang, Horng‐Yih Ou   +11 more
wiley   +1 more source

An Organo‐Pt(II) Photosensitizer With Robust Photo‐Assisted Antibacterial and Wound Recovery Performances in Diabetic Mice Wound Model

Rare Metals, Volume 45, Issue 7, July 2026.
ABSTRACT The pathogenesis of diabetic foot ulcers is complex, often involving polymicrobial infection and persistent inflammatory responses, which lead to delayed or nonhealing wounds, posing a formidable clinical challenge. Existing photodynamic therapy reagents and traditional treatments generally address only a single pathological aspect, and the ...
Yu Zhang, Mengyao Han, Qianqian Cheng, Yin Jie, Qianqian Zheng, Ziwei Xu, Beixi Shi, Yueqi Zhao, Xiaofei Yang, Guangjie Zhong, Chenchen Chang, Xiaoxiao Yin, Xinai Zhong, Zhengru Fu, Shuying Bai, Hui Chong, Chengyin Wang   +16 more
wiley   +1 more source

血尿酸、血同型半胱氨酸与糖尿病肾病相关性的研究进展

Zhongguo shiyan zhenduanxue, 2023
糖尿病肾病(diabetic kidney disease,DKD)是糖尿病代谢异常引发的肾小球硬化症，是其全身微血管病的组成部分，也是导致终末期肾脏病的重要原因。据第10版《全球糖尿病地图》统计，2021年中国糖尿病患者数量可达1.4亿，预计2045年将超过1.74亿[1]。Zhang等人[2]的荟萃分析表明，在中国，21.8%的2型糖尿病患者合并有糖尿病肾病。微量白蛋白尿的出现，被认为是早期糖尿病肾病的标志，但近些年来发现部分2型糖尿病合并肾功能衰退患者无异常蛋白尿，这为糖尿病肾病的诊治带来困难 ...
梁爽, 郭贺, 李洪军
doaj  

Risk of minor congenital heart defect in infants conceived via assisted reproductive technology: cohort study from the Copenhagen Baby Heart Study

Ultrasound in Obstetrics &Gynecology, Volume 68, Issue 1, Page 59-67, July 2026.
ABSTRACT Objective Infertility affects up to 20% of couples in high‐income countries, which has led to an increased use of assisted reproductive technology (ART). While previous studies have linked ART to a higher risk of major congenital heart defects (CHD), less is known about the associated risk of minor CHD.
F. Kyhl‐Svart, J. S. Jensen, R. O. B. Vøgg, D. Vassard, J. Forman, H. A. Boyd, V. Hjortdal, A.‐S. Sillesen, A. A. Raja, S. Dannesbo, A. F. Mariager, C. Torp‐Pedersen, M. P. Andersen, K. Iversen, H. Bundgaard, P. L. Madsen, A. Pinborg   +16 more
wiley   +1 more source

Deletion of Tgf‐β1 From CD206+ M2 Macrophages Ameliorates Obesity‐Induced Suppression of Myogenesis and AMPK Phosphorylation in Skeletal Muscle

Journal of Cachexia, Sarcopenia and Muscle, Volume 17, Issue 3, June 2026.
ABSTRACT Backgrounds Obesity and diabetes impair the ability of the muscle to regenerate, repair and remodel, resulting in a gradual decrease in muscle mass and function. However, the underlying mechanisms and effective therapeutic strategies remain poorly understood.
Muhammad Bilal, Le Duc Anh, Nguyen Quynh Phuong, Sana Khalid, Allah Nawaz, Memoona, Muhammad Rahil Aslam, Tomonobu Kado, Yoshiyuki Watanabe, Ayumi Nishimura, Yoshiko Igarashi, Aamir Sharif, Yasuhiro Onogi, Tsutomu Wada, Ryuji Hayashi, Kenichi Hirabayashi, Seiji Yamamoto, Takashi Nakagawa, Hisashi Mori, Isao Usui, Masaru Kato, Shiho Fujisaka, Kazuyuki Tobe   +22 more
wiley   +1 more source

ChREBP drives β‐cell proliferation under metabolic stress but not in pregnancy‐induced β‐cell expansion

Journal of Diabetes Investigation, Volume 17, Issue 6, Page 938-950, June 2026.
ChREBP is a context‐dependent regulator of adaptive β‐cell proliferation. It plays a pivotal role in driving β‐cell expansion under pathophysiological metabolic stress, such as insulin resistance and hyperglycemia, but has a limited role during physiological expansion in pregnancy.
Sodai Kubota, Seiya Banno, Katsumi Iizuka, Hiromi Tsuchida, Saki Kubota‐Okamoto, Teruaki Sakurai, Yoshihiro Takahashi, Toshinori Imaizumi, Takehiro Kato, Yukio Horikawa, Shin Tsunekawa, Ryota Usui, Hisato Tatsuoka, Shinsuke Tokumoto, Takaaki Murakami, Yuuka Fujiwara, Hitoshi Kuwata, Yuji Yamazaki, Yuichiro Yamada, Yutaka Seino, Daisuke Yabe   +20 more
wiley   +1 more source

成人迟发性自身免疫性糖尿病的研究进展

Zhongguo shiyan zhenduanxue, 2019
糖尿病是由多种原因引起的一类以慢性高血糖为特征的代谢性疾病,近年来,糖尿病的患病率在迅速上升,根据国际糖尿病联合会的糖尿病图谱,世界上大约有4亿人患有2型糖尿病,每年有1000万人被诊断患有糖尿病[1]。按现行的分类标准,糖尿病主要分为1型糖尿病(T1DM)、2型糖尿病(T2DM)、妊娠期糖尿病等特殊类型糖尿病。有些T1DM患者发生在成年期,即成人迟发性自身免疫性糖尿病(laten-
宁利俐, 燕艳, 付希英, 李沫, 蔡寒青   +4 more
doaj  

Impact of COVID‐19 restrictions and their relaxation on body composition and glycemic control in individuals with glucose intolerance in Japan: A single‐center observational study

Journal of Diabetes Investigation, Volume 17, Issue 6, Page 1063-1074, June 2026.
This study examined glycemic control, body composition, and lifestyle changes in 221 outpatients with glucose intolerance (GI) in Japan across the pre‐state of emergency (SOE), SOE, and post‐SOE periods. HbA1c increased despite body weight reduction, with progressive muscle loss.
Ami Kobayashi, Yamato Keidai, Takaaki Murakami, Ryo Tsukaguchi, Miharu Fujita, Keiko Wada, Daisuke Yabe   +6 more
wiley   +1 more source