Results 41 to 50 of about 270,599 (159)
Zhongguo shiyan zhenduanxue, 2019 目的检测2型糖尿病早期肾病患者的尿中性粒细胞明胶酶相关脂质运载蛋白(NGAL)和胱抑素-C的水平,并与无糖尿病肾病的患者进行比较,分析尿NGAL和胱抑素C水平与尿微量白蛋白相关性。方法入组126名2型糖尿病患者和30名无糖尿病肾病作为对照组进行横断面比较研究。分为3个研究组:2型糖尿病有微量白蛋白尿组,2型糖尿病无微量白蛋白尿组和无任何肾脏疾病的患者。统计研究对象中2型糖尿病病程时间和血糖状态。对所有受试者的血样集中储存在-20℃的冰箱中,批量检测尿微量白蛋白以及NGAL和胱抑素-C水平 ...
陈英 +5 more
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Zhongguo shiyan zhenduanxue, 2022 中华医学会内分泌学会流行病学调查显示,我国18岁及以上人群糖尿病患病率为11.2%[1-2],我国糖尿病流行特点是以2型糖尿病糖(T2DM)为主、汉族患病率最高、未诊断糖尿病比例高、肥胖和超重人群患糖尿病比率显著增高。由于糖尿病患者血糖控制不佳其并发症多、死亡率显著增高[3-4],所以糖尿病治疗面临巨大挑战。手术治疗糖尿病是治疗糖尿病有效方法之一,本研究目的是确定腹腔镜空肠回肠吻合术对瘦素水平的影响。1资料与方法1 ...
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Rare Metals, Volume 45, Issue 4, April 2026.ABSTRACT Diabetic wound infections are a common complication of diabetes, which severely impact patients' quality of life. Effective treatment of diabetic wound infections remains one major challenge in the clinic, partially due to the formation of bacterial biofilm and antibiotic resistance.
Liang Zhou +8 more
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Diabetes, Obesity and Metabolism, Volume 28, Issue 4, Page 3033-3043, April 2026.Abstract Aims We investigated whether dipeptidyl peptidase‐4 inhibitor (DPP‐4i) use was associated with a higher risk of acute pancreatitis compared with sodium–glucose cotransporter 2 inhibitor (SGLT2i) use in antidiabetic medication‐naïve individuals.
Takashi Tatewaki +3 more
wiley +1 more source
血清糖化白蛋白与内源性分泌型糖化终末产物受体比值对糖尿病并发冠心病危险的评估价值
Zhongguo shiyan zhenduanxue, 2007 目的测定糖尿病及糖尿病并发冠心病患者血清糖化白蛋白（GA）和内源性分泌型糖化终末产物受体（es-RAGE）水平,探讨GA与esRAGE比值对判断糖尿病并发冠心病和冠状动脉病变严重程度的价值。方法入选单纯2型糖尿病患者64例（糖尿病组）,2型糖尿病合并冠心病患者70例（糖尿病合并冠心病组）,并根据冠状动脉病变支数分为三个亚组:一支病变组（22例）,两支病变组（19例）和三支病变组（29例）。以42例健康者为对照（对照组）。测定各组血清GA和esRAGE水平,计算GA/esRAGE比值 ...
陈秋静 +6 more
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Endogenous GIP signaling is indispensable for DPP‐4 inhibitor‐mediated metabolic control in mice
Journal of Diabetes Investigation, Volume 17, Issue 4, Page 567-575, April 2026.This study reveals that the metabolic benefits of DPP‐4 inhibitors, including improved glucose tolerance and reduced body weight, are completely abolished in GIP receptor‐deficient mice. These findings establish that endogenous GIP signaling, rather than GLP‐1, is the indispensable key player for the efficacy of this drug class.
Saki Kubota‐Okamoto +17 more
wiley +1 more source
Zhongguo shiyan zhenduanxue, 2013 随着2型糖尿病发病率的不断增加,糖尿病肾病（DN）已成为我国最常见的继发性肾脏疾病之一[1]。同时,DN也逐渐成为终末期肾病的主要原因,但并非所有糖尿病患者的肾损伤都为糖尿病肾病[2]。本文就疑似合并非糖尿病肾病的185例2型糖尿病患者的临床及病理做一下回顾性分析。
潘文波 +3 more
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Advances in Elemene Nanodelivery Systems: From Material Design to Disease Treatment
Rare Metals, Volume 45, Issue 2, February 2026.ABSTRACT Elemene (ELE) is a bioactive sesquiterpenoid extracted from traditional Chinese herbs, demonstrating broad‐spectrum antitumor, anti‐inflammatory, and analgesic properties with significant therapeutic potential. However, its clinical utility is constrained by inherent physicochemical limitations, including volatility and hydrophobicity, which ...
Xiao Wang +9 more
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Zhongshan Daxue xuebao. Yixue kexue ban, 2010 我国目前糖尿病正处于快速增长期,且糖尿病发病呈现年轻化趋势65377;本文就作者近年来在糖尿病领域的系列研究工作做一综述,主要涉及糖尿病及其相关疾病的流行病学65380;糖尿病的分子遗传学和2型糖尿病早期诊断治疗等65377;提倡对糖尿病患者进行个体化的诊断,实施个体化的治疗65377;
翁建平
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Diabetes, Obesity and Metabolism, Volume 28, Issue 1, Page 701-710, January 2026.Abstract Aims To analyse prescribing trends in antidiabetic agents stratified by background characteristics among individuals with type 2 diabetes. Materials and Methods This retrospective study used a large‐scale database between 2015 and 2024 in Japan.
Kazuki Aoyama +14 more
wiley +1 more source