Results 31 to 40 of about 270,599 (159)

尿NAG和LAP对糖尿病早期肾损害的诊断价值

open access: yesZhongguo shiyan zhenduanxue, 2008
目的检测糖尿病无肾损害组和糖尿病合并肾损害组患者尿N-乙酰--βD氨基葡萄糖苷酶(NAG)、亮氨酸氨基肽酶(LAP)的活性,探讨尿NAG、LAP对糖尿病早期肾损害的诊断价值。方法58例糖尿病患者随机分为两组:37例糖尿病无肾损害组和21例糖尿病有肾损害组,采用速率法检测糖尿病患者尿NAG、LAP的活性。结果糖尿病无肾损害组和肾损害组尿NAG、LAP的活性高于对照组 ...
宗成国   +4 more
doaj  

Deletion of Tgf‐β1 From CD206+ M2 Macrophages Ameliorates Obesity‐Induced Suppression of Myogenesis and AMPK Phosphorylation in Skeletal Muscle

open access: yesJournal of Cachexia, Sarcopenia and Muscle, Volume 17, Issue 3, June 2026.
ABSTRACT Backgrounds Obesity and diabetes impair the ability of the muscle to regenerate, repair and remodel, resulting in a gradual decrease in muscle mass and function. However, the underlying mechanisms and effective therapeutic strategies remain poorly understood.
Muhammad Bilal   +22 more
wiley   +1 more source

糖尿病跟腱的超声研究的进展

open access: yesZhongguo shiyan zhenduanxue, 2016
糖尿病足是糖尿病治疗的难题之一,是糖尿病患者下肢截肢致残的主要原因[1]。许多糖尿病患者初诊后是有较长的存活期的[2],案例报道和流行病学调查分析显示糖尿病与跟腱断裂是有明显关系的[3],糖尿病导致的下肢综合征与糖尿病发病率和致死率有显著的相关性[2],预防糖尿病下肢的病变是糖尿病患者晚期生活质量明显改善的关键之一,所以对糖尿病患者下肢早期异常改变的发现是至关重要的 ...
黄文慧   +5 more
doaj  

ChREBP drives β‐cell proliferation under metabolic stress but not in pregnancy‐induced β‐cell expansion

open access: yesJournal of Diabetes Investigation, Volume 17, Issue 6, Page 938-950, June 2026.
ChREBP is a context‐dependent regulator of adaptive β‐cell proliferation. It plays a pivotal role in driving β‐cell expansion under pathophysiological metabolic stress, such as insulin resistance and hyperglycemia, but has a limited role during physiological expansion in pregnancy.
Sodai Kubota   +20 more
wiley   +1 more source

中西医结合治疗糖尿病肾病疗效观察 [PDF]

open access: yes, 2012
目的观察益气养阴、活血祛瘀中药联合西药治疗早期糖尿病肾病的疗效。方法将早期糖尿病肾病患者46例随机分为2组,治疗组23例,采用基础治疗方案加用益气养阴、活血祛瘀中药治疗,对照组23例仅采用基础方案治疗,2组均治疗8周。结果治疗组总有效率为87%,对照组总有效率为70%,2组比较有显著性差异 ...
陈敏, 俞翔
core   +1 more source

血清HCY及尿NAG、β2-MG、mALB对糖尿病肾病的应用价值

open access: yesZhongguo shiyan zhenduanxue, 2013
糖尿病(DM)是一组以慢性血糖水平增高为特征的代谢性疾病,糖尿病肾病(DN)是糖尿病微血管并发症之一,是糖尿病患者的重要死亡原因。近年来国外研究表明糖尿病大血管病变和微血管病变的发生也与高HCY血症有关[1]。为此我们对糖尿病肾病患者的血清HCY进行测定,并探讨HCY与糖尿病肾病的关系,同时检测糖尿病肾病患者尿NAG、β2-MG、mALB浓度,本文就HCY与其他三项指标相关性做了研究,现报道如下。
邹丽娟, 张浩
doaj  

Impact of COVID‐19 restrictions and their relaxation on body composition and glycemic control in individuals with glucose intolerance in Japan: A single‐center observational study

open access: yesJournal of Diabetes Investigation, Volume 17, Issue 6, Page 1063-1074, June 2026.
This study examined glycemic control, body composition, and lifestyle changes in 221 outpatients with glucose intolerance (GI) in Japan across the pre‐state of emergency (SOE), SOE, and post‐SOE periods. HbA1c increased despite body weight reduction, with progressive muscle loss.
Ami Kobayashi   +6 more
wiley   +1 more source

糖基化终末产物与糖尿病肾病关系的研究进展

open access: yesZhongguo shiyan zhenduanxue, 2017
糖尿病是一种全球性公共卫生挑战。在最近的国际糖尿病联盟发布的糖尿病地图中报告,世界上糖尿病患者流行人数估计达8.3%,约3.87亿,每7秒就有一人因糖尿病死亡[1]。2013年中华医学会糖尿病学分会公布糖尿病流行病学调查结果显示,我国18岁以上人群糖尿病患病率为9.
顾天菊, 王清
doaj  

An Ultrasound‐Triggered Antibacterial Hydrogel With Integrated Antioxidant and Angiogenic Functions for Infected Wound Care

open access: yesRare Metals, Volume 45, Issue 5, May 2026.
ABSTRACT Managing diabetic wounds requires simultaneously addressing their infectious, oxidative, and regenerative impairments. To address this, this study integrates a piezoelectric BiOCl@CuSe heterojunction (PFM‐verified) into an injectable F127/HA hydrogel, creating an ultrasound‐responsive smart dressing.
Jiayan Guo   +5 more
wiley   +1 more source

糖尿病患者の同病者支援システムの開発:システムの改良と運用方法の検討 [PDF]

open access: yes, 2017
2型糖尿病患者に対する同病者による支援(ピア・サポート)のためのシステムを開発し1年間運用した。本研究は、その後のシステム改良の過程と、患者が療養生活の中でシステムをより効果的に活用するための運用方法について検討した。新システムは、専門家によるコンテンツの作成と運用、マルチデバイス対応化、ピア・サポートを重視したコンテンツ設計、参加者及び専門家との双方向的な交流、会員制によるプライバシーの確保といった対応をとり、文献に基づくシステム機能を評価した結果 ...
0000-0002-4827-3249   +20 more
core   +1 more source

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