Results 31 to 40 of about 215,989 (167)
Journal of Diabetes Investigation, Volume 16, Issue 10, Page 1941-1949, October 2025.In East Asian individuals with type 2 diabetes, increases in alcohol consumption were inversely associated with HbA1c levels in men, whereas the amount of alcohol consumption was associated with HbA1c levels in a J‐shaped manner in women. The alcohol–HbA1c associations were similarly observed, regardless of genetic susceptibility to alcohol metabolism.
Toshiaki Ohkuma +4 more
wiley +1 more source
Journal of Diabetes Investigation, Volume 16, Issue 9, Page 1653-1662, September 2025.Distribution of cases by subgroup. Dots indicate each case. Lines connect each case to the centroid of each subgroup. BMI, body mass index; HbA1c, glycated hemoglobin. ABSTRACT Introduction Despite the increasing number of studies using machine learning to develop individualized treatment strategies, only a few have been conducted in patients with type
Takafumi Masuda +6 more
wiley +1 more source
Zhongshan Daxue xuebao. Yixue kexue ban, 2017 糖尿病微血管并发症累及全身各个器官，导致糖尿病患者寿命下降和生活质量降低。血管新生是糖尿病微 血管并发症的基本病理特征，而血管新生抑制因子在血管新生平衡调控和糖尿病微血管并发症发生发展中起了重要作 用。本文就血管新生抑制因子与糖尿病微血管并发症的研究进展及治疗前景作一综述，包括血管新生抑制因子与糖尿病 各种微血管并发症（糖尿病视网膜病变、糖尿病足、糖尿病勃起功能障碍和糖尿病肾病等）等的关系，最后概述了糖尿病微 血管并发症的临床治疗现状与内源性新生血管抑制因子在其中的应用前景。
高国全
doaj
Journal of Clinical Nursing, Volume 34, Issue 7, Page 2918-2932, July 2025.ABSTRACT Aim To explore the perceptions and factors that influence intentions to prevent diabetes among at‐risk individuals. Design A descriptive qualitative study design was used. The Consolidated criteria for Reporting Qualitative Research (COREQ) checklist guided the presentation of findings.
Jun Yi Claire Teo +5 more
wiley +1 more source
糖尿病患者の同病者支援システムの開発：システムの改良と運用方法の検討
, 2017 2型糖尿病患者に対する同病者による支援（ピア・サポート）のためのシステムを開発し1年間運用した。本研究は、その後のシステム改良の過程と、患者が療養生活の中でシステムをより効果的に活用するための運用方法について検討した。新システムは、専門家によるコンテンツの作成と運用、マルチデバイス対応化、ピア・サポートを重視したコンテンツ設計、参加者及び専門家との双方向的な交流、会員制によるプライバシーの確保といった対応をとり、文献に基づくシステム機能を評価した結果 ...
0000-0002-4827-3249 +20 more
core +1 more source
Zhongguo shiyan zhenduanxue, 2018 随着糖尿病发病率的增加,我国糖尿病患病人数已居全球首位,糖尿病肾病（DN）已成为我国慢性肾脏病第一大病因[1]。近年来肾穿刺活检术广泛开展,非糖尿病性肾脏疾病（NDRD）在糖尿病合并肾脏损害患者中的诊断率越来越高。据统计,糖尿病合并NDRD的各种病理类型中以IMN最多见[2,3]。与DN不同,糖尿病合并特发性膜性肾病（IMN ...
陈雨, 田庚, 卢雪红, 罗萍
doaj
Pyruvate kinase modulates the link between β‐cell fructose metabolism and insulin secretion
The FASEB Journal, Volume 39, Issue 7, 15 April 2025.Left: Supraphysiological fructose amplifies glucose‐induced insulin secretion (GIIS) through sweet taste receptor (STR)‐mediated PLCβ2 signaling in pancreatic β‐cells. Concurrently, the phosphorylation of fructose to fructose 1‐phosphate (F1P) occurs in conjunction with the conversion of ATP to ADP. Subsequently, F1P inhibits pyruvate kinase M2 (PKM2).
Naoya Murao +8 more
wiley +1 more source
血清糖化白蛋白与内源性分泌型糖化终末产物受体比值对糖尿病并发冠心病危险的评估价值
Zhongguo shiyan zhenduanxue, 2007 目的测定糖尿病及糖尿病并发冠心病患者血清糖化白蛋白（GA）和内源性分泌型糖化终末产物受体（es-RAGE）水平,探讨GA与esRAGE比值对判断糖尿病并发冠心病和冠状动脉病变严重程度的价值。方法入选单纯2型糖尿病患者64例（糖尿病组）,2型糖尿病合并冠心病患者70例（糖尿病合并冠心病组）,并根据冠状动脉病变支数分为三个亚组:一支病变组（22例）,两支病变组（19例）和三支病变组（29例）。以42例健康者为对照（对照组）。测定各组血清GA和esRAGE水平,计算GA/esRAGE比值 ...
陈秋静 +6 more
doaj
Pharmacology Research &Perspectives, Volume 13, Issue 2, April 2025.At high concentrations (> 10 μM), the β‐adrenergic blocker propranolol paradoxically increased intracellular cAMP levels in pancreatic β‐cells. This led to PKA‐induced RYR2 phosphorylation and extracellular Ca2+ influx, leading to CICR from the ER. CICR activated TRPM5, which augmented β‐cell electrical activity, extracellular Ca2+ influx, and insulin ...
Naoya Murao +6 more
wiley +1 more source
, 2015 平成２７年度日赤糖尿病講演会（2015年11月7日 9：40～12：15 とりぎん文化会館第一会議室 鳥取赤十字病院主催）conference ...
安東, 史博 +3 more
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