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Zhongshan Daxue xuebao. Yixue kexue ban, 2010 我国目前糖尿病正处于快速增长期,且糖尿病发病呈现年轻化趋势65377;本文就作者近年来在糖尿病领域的系列研究工作做一综述,主要涉及糖尿病及其相关疾病的流行病学65380;糖尿病的分子遗传学和2型糖尿病早期诊断治疗等65377;提倡对糖尿病患者进行个体化的诊断,实施个体化的治疗65377;
翁建平
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[Roles of ferroptosis in the development of diabetic nephropathy]. [PDF]
Zhejiang Da Xue Xue Bao Yi Xue Ban糖尿病肾病是常见的糖尿病微血管并发症，也是糖尿病患者死亡的主要原因之一。铁死亡是一种铁依赖性调节性细胞死亡，其在糖尿病肾病的发生发展中具有一定作用。腺苷一磷酸活化的蛋白质激酶（AMPK）介导的铁死亡相关信号通路可以延缓糖尿病肾病的进程，但AMPK信号过度激活可能会诱导细胞发生自噬性死亡；激活核转录因子红系2相关因子（Nrf）2和血红素加氧酶（HO）-1介导的信号通路能够抑制细胞铁死亡并改善糖尿病肾病，但HO-1在铁死亡中的调节作用是双向的，激活HIF-1α/HO-1信号通路可能导致细胞内铁过载 ...
Liu P, Zhang Z, Chen Q.
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, 2021 “不可以吃糖、不能喝粥、不能吃水果,如果这些都不能做,活着还有什么意思?”“以前吃不饱饭,现在能吃饱,却因为糖尿病而不让吃,我怎么会这么倒霉?”患上糖尿病,很多人都知道了控制饮食、运动锻炼、药物治疗和监测血糖,然而,大多数糖尿病患者还不知道心理调适也是控制d血糖非常重要的一个环节。
闵宝权 +5 more
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Journal of Diabetes Investigation, Volume 17, Issue 6, Page 938-950, June 2026.ChREBP is a context‐dependent regulator of adaptive β‐cell proliferation. It plays a pivotal role in driving β‐cell expansion under pathophysiological metabolic stress, such as insulin resistance and hyperglycemia, but has a limited role during physiological expansion in pregnancy.
Sodai Kubota +20 more
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, 1981 近年来,糖尿病患病率似有逐渐增高的趋势。据报道,西欧各国糖尿病患病率为2～4％;美国约5％,其中45～64岁为4.3％,65岁以上为7.9％,1938～1978年间糖尿病患病率增加6倍。我国上海地区在1978年进行调查,糖尿病患者约占1％。轻型糖尿病可无症状,但如不及时发现并给予良好控制,随着病情发展和病程的延长,常并发各种慢性病变,特别是大血管及/或微血管病变,可使病人丧失劳动力,甚至影响寿限。目前,在一些国家因糖尿病并发症而死亡者,仅次于肿瘤及心血管病,而为致死的第三原因 ...
广州地区糖尿病调查协作组
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Journal of Diabetes Investigation, Volume 17, Issue 6, Page 1063-1074, June 2026.This study examined glycemic control, body composition, and lifestyle changes in 221 outpatients with glucose intolerance (GI) in Japan across the pre‐state of emergency (SOE), SOE, and post‐SOE periods. HbA1c increased despite body weight reduction, with progressive muscle loss.
Ami Kobayashi +6 more
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Rare Metals, Volume 45, Issue 5, May 2026.ABSTRACT Managing diabetic wounds requires simultaneously addressing their infectious, oxidative, and regenerative impairments. To address this, this study integrates a piezoelectric BiOCl@CuSe heterojunction (PFM‐verified) into an injectable F127/HA hydrogel, creating an ultrasound‐responsive smart dressing.
Jiayan Guo +5 more
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Rare Metals, Volume 45, Issue 4, April 2026.ABSTRACT Diabetic wound infections are a common complication of diabetes, which severely impact patients' quality of life. Effective treatment of diabetic wound infections remains one major challenge in the clinic, partially due to the formation of bacterial biofilm and antibiotic resistance.
Liang Zhou +8 more
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, 2006 A村の糖尿病有病者と、非糖尿病者の生活において生活習慣に違いがあるかどうかを比較することにより糖尿病予防を探る手がかりとするため、糖尿病の実態と生活習慣に関するアンケート調査を実施した。その結果以下のことが明らかとなった。(1)糖尿病有病者は97名(8.2%)で狭心症と並んで2番目に多い疾患であった。また過去に尿糖が出ている、血糖が高いと指摘され医療機関に行っていない人は120名だった。(2)家族性では非糖尿病者では約1割、糖尿病有病者では約4割の人が家族に糖尿病歴があった。(3 ...
白川, あゆみ, 安田, 貴恵子
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Diabetes, Obesity and Metabolism, Volume 28, Issue 4, Page 3033-3043, April 2026.Abstract Aims We investigated whether dipeptidyl peptidase‐4 inhibitor (DPP‐4i) use was associated with a higher risk of acute pancreatitis compared with sodium–glucose cotransporter 2 inhibitor (SGLT2i) use in antidiabetic medication‐naïve individuals.
Takashi Tatewaki +3 more
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