Results 51 to 60 of about 49,529 (252)

NIR‐Responsive Nano‐Integrated Magnesium Phosphate Cement Promotes Bone Regeneration via Osteoblast‐Exosome‐Osteoclast Crosstalk

open access: yesRare Metals, EarlyView.
ABSTRACT The limited osteogenic capacity of magnesium phosphate cement (MPC) has constrained its biomedical applications, underscoring the necessity to develop MPC with enhanced physical properties and bone‐forming capabilities. In this study, a multifunctional MPC system was developed by incorporating zoledronic acid‐loaded near‐infrared (NIR ...
Bin Wang   +8 more
wiley   +1 more source

外泌体环状RNA诱导HK-2细胞凋亡在感染性休克AKI中的研究

open access: yesZhongguo shiyan zhenduanxue
目的 探究外泌体环状RNA诱导HK-2细胞凋亡在感染性休克相关性急性肾损伤的作用机制。方法 分为感染性休克相关性急性肾损伤患者组和健康人对照组,采集血标本。检测外泌体标记蛋白,鉴定出两组外泌体,对外泌体环状RNA进行实时PCR分析。对两组的HK-2细胞进行凋亡检测。结果 10例感染性休克AKI入院患者,10例健康人对照。鉴定表面外泌体标记蛋白包括HSP70和TSG101。两组均鉴定出外泌体。与对照组相比,感染性休克AKI组circ-Ttc3 ...
李秀君, 李岩, 张春媚, 杨海玲
doaj   +2 more sources

Progress in Surface‐Enhanced Raman Scattering‐Based Volatile Organic Compounds Detection: Materials, Application, and Prospects

open access: yesRare Metals, EarlyView.
ABSTRACT The detection of volatile organic compounds (VOCs) holds significant implications in environmental monitoring and disease diagnosis. Traditional gas detection technologies are constrained by complex operation and high cost, thereby failing to satisfy real‐time detection demands.
Yuening Wang   +11 more
wiley   +1 more source

大鼠体外循环模型肺部炎症反应的研究

open access: yesZhongguo shiyan zhenduanxue, 2005
目的在体外循环(CBP)过程中产生的全身炎症反应与术后呼吸功能不全有关,本实验研究p38丝裂原激活蛋白激酶(p38MAPK)与体外循环中肺损伤的内在关系。方法复制大鼠体外循环模型,随机分为2组,实验组和对照组,每组9只。实验组体外循环30分钟后,开放肺动脉,接呼吸机,30分钟后取左肺肺组织;对照组只是行胸部正中切口,全身肝素化。检测大鼠肺组织p38MAPK活性,测定p38MAPK的表达。肺组织的炎症反应通过检测TNF-α、IL-1β和组织学改变来测定。肺水肿通过估计组织中水的百分比来测定 ...
吕民   +5 more
doaj  

Activatable Hybrid Nanoparticles for Cancer Theranostic [PDF]

open access: yes, 2016
众所周知癌症已经成为人类在健康领域中面临的重大问题。临床研究控制和治愈肿瘤最有效的方式是实现早期的诊断和治疗,而如何使肿瘤早期诊断成为现实,提高治疗效果已成为这一研究领域的一个热门话题。纳米医学,即纳米技术在医学中的应用,推动了脂质体,纳米颗粒,胶束等载药型纳米颗粒的发展。而重要的是这些医学纳米材料作为有效的诊断治疗试剂用于多种疾病的诊断和治疗。一个优秀的纳米材料应该具备多重优势:(1)实现肿瘤或其他疾病的早期可视化,(2)有效转运药物到目标部位,(3)诊断治疗试剂在体内的分布和(4 ...
张力文
core  

Fermi Surface Structure Revealed by Quantum Oscillations in Half‐Heusler Semimetal LuAuSn

open access: yesRare Metals, EarlyView.
ABSTRACT The Fermi surface structure in the half‐Heusler semimetallic compound LuAuSn was systematically investigated using quantum oscillation studies of high‐quality single crystals and first‐principles calculations. Clear bulk quantum oscillation signals were observed for multiple complementary physical properties, including magnetization, Hall ...
Yue Lu   +12 more
wiley   +1 more source

Renal autotransplantation for ureteral lesions--the indication and the results of operation [PDF]

open access: yes, 1984
5例中4例は術後良好な移植腎機能を示したが1例は静脈吻合部縫合不全にて死亡したRenal autotransplantation has been a treatment of choice for renovascular hypertension, renal artery aneurysm, complicated staghorn calculi, ureteral disorders and others.
北川, 元昭   +6 more
core  

Selective Lithium Deposition Through 3D Copper Collector With Lithiophilic Alloy “Skins” and Curvature Boundaries for Dendrite‐Free Lithium‐Metal Anodes

open access: yesRare Metals, EarlyView.
ABSTRACT Although lithium metal has been regarded as an ideal anode material for high‐energy‐density batteries, its practical applications remain hindered by many serious challenges. Three‐dimensional (3D) porous Cu current collectors demonstrate potential in ensuring uniform Li deposition.
Meng‐Qi Zhu   +7 more
wiley   +1 more source

下颌单侧游离端冠外精密附着体义齿三维有限元模型的建立

open access: yesZhongguo shiyan zhenduanxue, 2006
目的建立下颌单侧游离端冠外精密附着体三维有限元模型,为附着体义齿应力分析提供基础。方法采用CT扫描和I-DEAS软件,手工建模。结果建立了能够应用接触单元的下颌单侧游离端冠外精密附着体三维有限模型。结论采用I-DEAS软件可建立游离端冠外精密附着体三维有限元模型,此模型能反映冠外精密附着体构件之间义齿的接触关系,提高模型的仿真性。
王伟   +4 more
doaj  

Mechanistic Analysis of Immunomodulation by Human Induced Pluripotent Stem Cells Derived Mesenchymal Stem Cells in Mice [PDF]

open access: yes, 2015
背景:间充质干细胞是具有自我更新能力和分化能力的组织细胞前体细胞,能够分化为一系列的间质细胞,包括成骨细胞、成软骨细胞、脂肪细胞、肌细胞和内皮细胞等。细胞治疗是再生医学发展的一个重要分支。越来越多的研究发现,间充质干细胞能够修复组织损伤,达到一定治疗效果。因此,间充质干细胞被视为天然组织工程材料的重要种子细胞,具有广阔的应用前景。此外,间充质干细胞具有负性免疫调节能力。在体外共培养条件下,间充质干细胞能够抑制免疫细胞功能,包括抑制T细胞反应,抑制树突状细胞的成熟和抗原提成,抑制B细胞激活和增殖 ...
李成林
core  

Home - About - Disclaimer - Privacy