Results 31 to 40 of about 52,960 (211)
Zhongguo shiyan zhenduanxue, 2022 目的 探索外泌体来源的miR-21作为胃癌奥沙利铂化疗过程中评价药物敏感性生物标志物的价值。方法透射电镜观察外泌体的形态；构建SGC7901奥沙利铂耐药细胞株，并利用RT-qPCR检测耐药细胞和亲本细胞中miR-21的表达水平；CCK8检测miR-21对SGC7901耐药细胞株增殖抑制率的影响；Western blot检测外泌体的标记蛋白；使用受试者工作特征曲线（ROC）分析奥沙利铂治疗胃癌的过程中miR-21评估药物敏感性的价值。结果miR-21过表达后，亲本细胞对奥沙利铂的敏感性由IC50 16 ...
杜沛, 李婷, 文雯
doaj
Conservation Biology, EarlyView.Abstract Human development is a driver of global change and a major threat to biodiversity. Protected areas maintain and support biodiversity, but outside stressors, such as climate change and land use change, can negatively influence natural resources within protected areas.
Leah J. Rudge +2 more
wiley +1 more source
Zhongguo shiyan zhenduanxue, 2020 体外膜肺氧合技术(Extracorporeal Membrane Oxygenation,ECMO),作为一种呼吸和心脏功能的支持技术,出现于1970s[1]。由传统的心肺转流(cardiopulmonary bypass,CPB)技术发展而来。ECMO是体外生命支持系统的其中一种表现形式,它的基础是体外循环,却和体外循环相比具有很多优势,它的功能不止局限于循环支持,还可以支持呼吸衰竭患者的呼吸功能 ...
赖冰洁 +4 more
doaj
フニン チリョウ オ ウケル フウフ ノ カカエル モンダイ ト シエン ノ アリカタ [PDF]
, 2009 本稿では,不妊治療を受ける夫婦の身体的・精神的・社会的側面の問題と支援のあり方について,先行研究を基に論考した.不妊治療を受ける夫婦にとっては,治療そのものやホルモン療法による副作用や不妊治療にかかる高額な費用が,日常生活を脅かし大きなストレスとなっている.これらが関係に大きな影響を与えることが考えられる.不妊治療を受ける夫婦の心理的ストレスの実態や,ストレス対処,社会的支援については報告されるようになった.しかし,不妊治療を受けている夫婦の日常生活に焦点をあてた調査報告は見当たらない ...
林谷 啓美, 鈴井 江三子
core +1 more source
Harnessing social media data to track species range shifts
Conservation Biology, EarlyView.Abstract Biodiversity monitoring programs and citizen science data remain heavily biased toward the Global North. Especially in megadiverse countries with limited biodiversity records, incorporating social media data can help address existing data gaps.
Shawan Chowdhury +15 more
wiley +1 more source
Zhejiang Daxue xuebao. Lixue ban, 2010 用豆油作为氧载体加入发酵液中形成双液相发酵体系,以改善灵芝胞外多糖的发酵状况.实验表明：常见的氧载体材料在双液相发酵过程中不为灵芝菌体所利用,仅起到促进溶氧的效果；在灵芝胞外多糖的双液相发酵体系中, KLa值明显提高,溶氧水平(DO)有显著改善,发酵液的运动黏度µ有所降低,有助于降低搅拌能耗；氧载体改善了质量传递,提高了细胞的代谢水平,使胞外多糖的产量提高了44%,发酵周期缩短了约17%.说明双液相发酵体系对灵芝胞外多糖发酵是一种新型有效的途径.
LIWei-qi(李卫旗) +4 more
doaj +1 more source
Biodiversity‐driven spatial conservation planning to delineate temporally stable regions
Conservation Biology, EarlyView.Abstract The accelerating loss of biodiversity underscores the critical need for effective conservation strategies, particularly in the face of climate change and anthropogenic pressures. We devised a conservation planning framework that adopts a temporal stacking approach to species distribution models and landscape connectivity analyses. These models
Mattia Iannella +5 more
wiley +1 more source
外泌体microRNA-212/132与创伤性颅脑损伤严重程度及Rotterdam CT评分的相关性研究
Zhongguo shiyan zhenduanxue, 2022 目的 探讨创伤性颅脑损伤（TBI）患者外泌体microRNA-212/132(miR-212、miR-132)表达水平，及其与患者脑损伤严重程度和Rotterdam CT评分的相关性。方法 76例TBI患者根据格拉斯哥昏迷评分（GCS）分为轻度组（13-15分）19例，中度组（9-12分）35例，重度组（3-8分）22例。另选择38例体检健康者作为对照。所有受试者均给予颅脑CT检查并行Rotterdam CT评分；提取血浆外泌体RNA并采用实时荧光定量PCR技术检测miR-212、miR-132表达水平，
杨明, 刘瑛, 余华, 阳荣
doaj
Signal-averaged ECGの開心術への応用 [PDF]
, 1993 筑波大学University of Tsukuba博士（医学）Doctor of Philosophy in Medical Sciences1992付:参考論文doctoral ...
50719 +2 more
core
Perceived costs as drivers of wildlife management preferences in rural Tanzanian communities
Conservation Biology, EarlyView.Abstract Effectively managing human–wildlife interactions is crucial for fostering coexistence on shared landscapes. Management options are most effective when aligned with the preferences of people directly affected by wildlife, yet little is known about how socioecological factors influence these preferences.
Christian Kiffner +10 more
wiley +1 more source