Results 11 to 20 of about 10,635 (160)

Fatty acid β‐oxidation and mitochondrial fusion are involved in cardiac microvascular endothelial cell protection induced by glucagon receptor antagonism in diabetic mice 脂肪酸β‐氧化和线粒体融合参与胰高血糖素受体拮抗剂对糖尿病小鼠心脏微血管内皮细胞的保护作用

Journal of Diabetes, Volume 15, Issue 12, Page 1081-1094, December 2023., 2023
Highlights Glucagon receptor (GCGR) monoclonal antibody (mAb) improves cardiac function and attenuates microvascular damage in db/db mice. GCGR mAb ameliorates the oxidative stress of cardiac microvascular endothelial cells in diabetic mice. GCGR mAb counteracts the diabetes‐induced upregulation of carnitine palmitoyltransferase 1B, optic atrophy type ...
Peng Wang, Rui Wei, Xiaona Cui, Zongzhe Jiang, Jin Yang, Lingyun Zu, Tianpei Hong   +6 more
wiley   +1 more source

The influence of posttraumatic stress disorder treatment on anxiety sensitivity: Impact of prolonged exposure, sertraline, and their combination

Journal of Traumatic Stress, Volume 36, Issue 1, Page 157-166, February 2023., 2023
Abstract Trauma‐informed beliefs often decrease during posttraumatic stress disorder (PTSD) treatment. This may also extend to anxiety sensitivity (AS), defined as a fear of anxiety‐related sensations and beliefs that anxiety is dangerous and/or intolerable.
Matthew T. Luciano, Sonya B. Norman, Carolyn B. Allard, Ron Acierno, Naomi M. Simon, Kristin L. Szuhany, Amanda W. Baker, Murray B. Stein, Brian Martis, Peter W. Tuerk, Sheila A. M. Rauch, for the PROGrESS Study Team   +11 more
wiley   +1 more source

Exploring metapopulation‐scale suppression alternatives for a global invader in a river network experiencing climate change

Conservation Biology, Volume 37, Issue 1, February 2023., 2023
Abstract Invasive species can dramatically alter ecosystems, but eradication is difficult, and suppression is expensive once they are established. Uncertainties in the potential for expansion and impacts by an invader can lead to delayed and inadequate suppression, allowing for establishment.
Brian D. Healy, Phaedra Budy, Charles. B. Yackulic, Brendan P. Murphy, Robert C. Schelly, Mark C. McKinstry   +5 more
wiley   +1 more source

Effect of an ear cleaner instillation containing lipacids in a model of re‐acidification of the external auditory canal in dogs

Veterinary Dermatology, Volume 33, Issue 5, Page 402-406, October 2022., 2022
Abstract Background In humans, the acidic pH of the ear canal plays a protective role against infection and a change towards alkalinity of the external auditory canal (EAC) is a local factor in the progression of acute to chronic otitis externa (OE).
Pauline Panzuti, Marion Mosca, Oscar Fantini, Guillaume Noel, Julien Cappelle, Didier Pin   +5 more
wiley   +1 more source

The effect of a mixed cannabidiol and cannabidiolic acid based oil on client‐owned dogs with atopic dermatitis

Veterinary Dermatology, Volume 33, Issue 4, Page 329-e77, August 2022., 2022
Background– Cannabidiol (CBD) and cannabidiolic acid (CBDA) are reported to have antinociceptive, immunomodulatory and anti‐inflammatory actions. Objectives – To determine if CBD/CBDA is an effective therapy for canine atopic dermatitis (cAD). Conclusions and clinical relevance – Cannabidiol/CBDA as an adjunct therapy decreased pruritus, and not skin ...
Melissa Loewinger, Joseph J. Wakshlag, Daniel Bowden, Jeanine Peters‐Kennedy, Andrew Rosenberg   +4 more
wiley   +1 more source

Health utilities in Chinese patients with coronary heart disease and impaired glucose tolerance (ACE): A longitudinal analysis of a randomized, double‐blind, placebo‐controlled trial 中国冠心病合并糖耐量异常患者的健康相关生活质量:一项随机、双盲、安慰剂对照试验的纵向分析

Journal of Diabetes, Volume 14, Issue 7, Page 455-464, July 2022., 2022
Highlights The Acarbose Cardiovascular Evaluation (ACE) trial assessed the effects of acarbose in patients with coronary heart disease (CHD) and impaired glucose tolerance (IGT) in China. Acarbose treatment did not impact on health‐related quality of life in ACE trial participants with CHD and IGT. Myocardial infarction (MI), stroke, heart failure, and
José Leal, Frauke Becker, Lee‐Ling Lim, Rury R. Holman, Alastair M. Gray   +4 more
wiley   +1 more source

Plant diversity ameliorates the evolutionary development of fungicide resistance in an agricultural ecosystem

Journal of Applied Ecology, Volume 58, Issue 11, Page 2566-2578, November 2021., 2021
The development of fungicide resistance greatly threatens food security and ecological sustainability, and it is urgent need to develop agricultural practices which can ameliorate this problem. Our results show that potato crop with a genetic diversity is associated with a late blight pathogen of higher fungicide sensitivity and lower potential of ...
Li‐Na Yang, Oswald Nkurikiyimfura, Zhe‐Chao Pan, Yan‐Ping Wang, Abdul Waheed, Ruey‐Shyang Chen, Jeremy J. Burdon, Qi‐Jun Sui, Jiasui Zhan   +8 more
wiley   +1 more source

A masked, randomised clinical trial evaluating the efficacy and safety of lokivetmab compared to saline control in client‐owned dogs with allergic dermatitis

Veterinary Dermatology, Volume 32, Issue 5, Page 477-e131, October 2021., 2021
Background – Interleukin (IL)‐31 is an important mediator in canine atopic dermatitis (cAD) and also may be dysregulated in other allergic diseases. Hypothesis/Objectives – To demonstrate the efficacy and safety of lokivetmab (canine anti‐IL‐31 monoclonal antibody) for treatment of pruritus associated with allergic dermatitis in dogs.
Leen Van Brussel, Hilde Moyaert, Monica Escalada, Sean P. Mahabir, Michael R. Stegemann   +4 more
wiley   +1 more source

Research Progress in Oxidation Stability of Antarctic Krill (Euphausia superba) Oil and Review of Methods for Its Control [PDF]

, 2023
Antarctic krill oil is rich in phospholipid eicosapentaenoic acid and docosahexaenoic acid with high bioavailability. It is a high-quality source of ω-3 fatty acids and is a potential substitute for fish oil.
LIN Liu, CAO Zhenhai, TAO Ningping, MIAO Junjian, WANG Xichang
core   +1 more source

MMC celebrating 6 years of experience and expansion 庆祝MMC六年的经验和壮大

, 2022
Journal of Diabetes, Volume 14, Issue 5, Page 356-357, May 2022.
Itamar Raz
wiley   +1 more source