[Research progress on the quercetin target role and signaling pathway in anti-liver fibrosis]. [PDF]
Zhao RQ +9 more
europepmc +1 more source
[Serum from rats with electroacupuncture activates the PI3K/Akt signaling pathway to improve synaptic plasticity in HT22 neurons with oxygen and glucose deprivation]. [PDF]
Shi X +8 more
europepmc +1 more source
Biomolecular condensates in Hippo pathway regulation. [PDF]
Shao Y, Zhang Y, Zhu W, Lu H.
europepmc +1 more source
[Role and mechanisms of FoxO3a-related signaling pathways in breast cancer cell apoptosis]. [PDF]
Wang Z +5 more
europepmc +1 more source
Sonic Hedgehog信号通路参与椎间盘退变的研究进展
随着社会老龄化的加剧,越来越多的患者受到腰背痛的困扰,给患者和社会带来负担。椎间盘退变(IVDD)是导致慢性腰背痛的主要原因,阐明IVDD的致病机制对解决当前所面临的健康问题具有重要意义。近年来,关于Sonic Hedgehog(Shh)通路在IVDD中的研究报道不断出现,Shh信号通路在椎间盘的形成和出生后维持中具有重要作用,并且该通路的表达变化伴随着椎间盘的年龄相关性退行性改变,靶向Shh信号通路可能在IVDD治疗中具有重要意义。本研究对Shh通路在IVDD中的研究进展进行总结 ...
刘永, 张海鸿
doaj
[Fecal microbiota transplantation inhibits colonic tumor growth in mice by suppressing the TLR4/MyD88/NF-κB signaling pathway]. [PDF]
Zhang J +7 more
europepmc +1 more source
脂噬是一种新型的脂质代谢,是细胞内脂滴选择性自噬降解的过程。脂噬与脂代谢相互作用,对维持机体能量平衡至关重要。生长因子、能量等多种信号参与了mTOR信号通路的调控并对脂噬产生影响。大量研究表明mTOR通路介导的脂噬对多种疾病的发生和发展起关键作用。本文综述了mTOR信号通路介导的脂噬在肝脏疾病、病毒感染疾病及神经系统疾病的调控机制,靶向脂噬可能成为未来治疗多种疾病的新策略。
吴璟玥, 包晓丹, 乔璐, 包丽丽
doaj
[Expression of Notch signaling pathway in children with Henoch-Schönlein purpura and its correlation with inflam-matory cytokines]. [PDF]
Chen H, Li F, Tang Y, Zeng P.
europepmc +1 more source
[<i>Qingda</i> Granules inhibit cerebral microvascular endothelial cell apoptosis in hypertensive mice by suppressing the P53 signaling pathway]. [PDF]
Lin Y +8 more
europepmc +1 more source
[Inhibition of ferroptosis by geniposide via activation of the SIRT3 signaling pathway to alleviate inflammatory injury in endothelial cells]. [PDF]
Sun WT, Zhao MM, Shi ZL.
europepmc +1 more source

