Association between TNF-α polymorphisms and responsiveness to TNF-α blockers in ankylosing spondylitis and psoriatic arthritis: a meta-analysis [PDF]
Scientific ReportsTo investigate the association between tumor necrosis factor-alpha (TNF-α) polymorphisms and the responsiveness to anti-TNF-α therapy in patients with ankylosing spondylitis (AS) and psoriatic arthritis (PsA).
Young Ho Lee, Gwan Gyu Song
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Multiple Modes of Action of Anti-TNF-α Antibodies for Inflammatory Bowel Diseases Beyond TNF-α Neutralization [PDF]
AntibodiesInflammatory bowel diseases (IBDs), chronic inflammatory disorders of the gastrointestinal tract, are classified into Crohn’s disease (CD) and ulcerative colitis (UC).
Tomohiro Watanabe, Masatoshi Kudo
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Assessment of IL6 and TNF α in Chronic Lymphocytic Leukemia [PDF]
International Journal of Medical Arts, 2022 Background: Among the cytokines and inflammatory markers, Interleukin 6 [IL6] and TNF α are the most common markers in the practice of medicine. Many studies determine the values of these two markers among the patients with chronic lymphocytic leukemia ...
Mohamed Abd-El-Haleem Mousa +3 more
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Study of TNF α gene polymorphism in Type 2 Diabetes [PDF]
Minia Journal of Medical Research, 2020 DM is one of the five principal causes of death universally. It is a growing heath problem of multifactorial origin, understanding its genetic background might help in early detection and disease prevention.
Sahar El-Hin +5 more
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Assessment of Anti-TNF-α Activities in Keratinocytes Expressing Inducible TNF- α: A Novel Tool for Anti-TNF-α Drug Screening. [PDF]
PLoS ONE, 2016 Tumor necrosis factor alpha (TNF-α) is a pro-inflammatory cytokine important in normal and pathological biological processes. Newly synthesized pro-TNF-α is expressed on the plasma membrane and cleaved to release soluble TNF-α protein: both are ...
Sutthirat Udommethaporn +3 more
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Experimental Gerontology, 2023 Tumor necrosis factor (TNF)-α is a proinflammatory cytokine involved in the pathogenesis of sarcopenia, but its short half-life and inconsistent reproducibility limit the potential of TNF-α to be an ideal sarcopenia biomarker.
Wei-Ju Lin +7 more
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Tristetraprolin Down-Regulation Contributes to Persistent TNF-Alpha Expression Induced by Cigarette Smoke Extract through a Post-Transcriptional Mechanism. [PDF]
PLoS ONE, 2016 Tumor necrosis factor-alpha (TNF-α) is a potent pro-inflammatory mediator and its expression is up-regulated in chronic obstructive pulmonary disease (COPD).
Xue-Ke Zhao +20 more
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Correlation Between TNF- α and Degree of Gastritis
The Indonesian Journal of Gastroenterology, Hepatology and Digestive Endoscopy, 2018 Background: TNF- α is a cytokine that plays an active role in the pathogenesis of gastritis. The correlation of TNF-α levels in the gastric mucosa with the severity of gastritis has long been known.
Ricky Rivalino +2 more
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Impact of TNF-α Inhibitors on Body Weight and BMI: A Systematic Review and Meta-Analysis
Frontiers in Pharmacology, 2020 ObjectiveThe aim of this systematic review and meta-analysis of longitudinal studies was to ascertain to effects of TNF-α inhibitor therapy on body weight and BMI.MethodsThree databases (PubMed, OVID, and EMBASE) were systematically searched from ...
Olivia Patsalos +4 more
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Tumor necrosis factor-α promotes cholestasis-induced liver fibrosis in the mouse through tissue inhibitor of metalloproteinase-1 production in hepatic stellate cells. [PDF]
PLoS ONE, 2013 Tumor necrosis factor (TNF)-α, which is a mediator of hepatotoxicity, has been implicated in liver fibrosis. However, the roles of TNF-α on hepatic stellate cell (HSC) activation and liver fibrosis are complicated and remain controversial.
Yosuke Osawa +5 more
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