Results 1 to 10 of about 1,383,229 (318)

Promising TNF-α inhibitors: Targeting pathogenic TNF-α/TNFR signaling to restore Th17/Treg balance in rheumatoid arthritis

Journal of Pharmaceutical Analysis
The pleiotropic regulatory effect of tumor necrosis factor-alpha (TNF-α), an essential cytokine involved in immune regulation, is of significant importance in the immune response.
Jiajie Kuai, Zhuo Chen, Ju He, Fengling Wang, Wei Wei   +4 more
doaj   +1 more source

TNF-α Deficiency Prevents Renal Inflammation and Oxidative Stress in Obese Mice

Kidney & Blood Pressure Research, 2017
Background/Aims: Obese patients and experimental animals exhibit high levels of inflammatory cytokines, such as tumor necrosis factor (TNF)-α. However, the role of TNF-α in the pathophysiologic process in obesity induced kidney damage is still unknown ...
Huaiguo Wang, Jian Li, Zhibo Gai, Gerd A. Kullak-Ublick, Zewei Liu   +4 more
doaj   +1 more source

THE EFFECT OF MASSAGE STIMULATION TO REDUCTION OF TUMOR NECROTIC FACTOR-ALFA (TNF-α) AND INTERLEUKIN-6 (IL-6) IN PRETERM, LOW BIRTH WEIGHT APPROPRIATE WITH GESTATIONAL AGE INFANTS

Indonesia Journal of Biomedical Science, 2015
Preterm condition gives a new stressful environment to infants. This condition needs a good and gradual adaptation. External environmental conditions, treatment, care and good nutrition are needed. Massage stimulation in preterm infants is a method that can prepare preterm infants’ adaptation through the critical post-birth period.
I G. A. Trisna-Windiani, Soetjiningsih Soetjiningsih, N. Mantik-Astawa, Kusnandi Rusmil   +3 more
openaire   +1 more source

The efficacy of maintenance therapy after remission induction with tacrolimus in ulcerative colitis with and without previous tumor necrosis factor‐α inhibitor

JGH Open, 2019
Background and Aim Tacrolimus (TAC) is an important therapeutic option for remission induction in patients with refractory ulcerative colitis (UC). However, there is little evidence available on long‐term outcomes and maintenance treatments after TAC ...
Taketo Suzuki, Tsutomu Mizoshita, Satoshi Tanida, Naomi Sugimura, Takahito Katano, Hirotada Nishie, Hiromi Kataoka   +6 more
doaj   +1 more source

TNF-α Levels Are Increased in Patients with Subjective Cognitive Impairment and Are Negatively Correlated with β Amyloid-42

Antioxidants
The role of tumor necrosis factor-α (TNF-α) in Alzheimer’s disease (AD) has recently become a topic of debate. TNF-α levels increase in the blood of patients with AD, and amyloid beta (Aβ) plaques contain TNF-α deposits.
Sara Serafini, Gabriella Ferretti, Paola Monterosso, Antonella Angiolillo, Alfonso Di Costanzo, Carmela Matrone   +5 more
doaj   +1 more source

High Level of Tumor Necrosis Factor (TNF)-α is a Risk Factor for Preeclampsia

Indonesian Journal of Obstetrics and Gynecology, 2016
Objective: To define that elevated TNF-α serum level was the risk factor of preeclampsia in pregnancy. Method: This research is a case-control study. From 56 pregnant women, there are 28 women with preeclampsia and the other 28 women with normal pregnancy. Then the serum level of TNF-α was obtained at Prodia’s clinical Laboratory Denpasar.
openaire   +2 more sources

PMS13 EXPERIMENTAL STUDY OF TOPICAL TREATMENT OF RHEUMATOID ARTHRITIS WITH TNF-Α ANTAGONIST [PDF]

Value in Health, 2019
openaire   +1 more source

Pengaruh Pemberian Minyak Atsiri Daun Kemangi (Ocimum Basillicum) terhadap Kadar Tnf-Α pada Tikus Wistar yang diberi Aktivitas Fisik Berlebih

Seminar Ilmiah Nasional Teknologi, Sains, dan Sosial Humaniora (SINTESA)
Penuaan merupakan salah satu penyebab utama kerusakan struktur dan fungsi molekul seluler. Salah satu teori mekanistik yang mendasari penuaan adalah "teori radikal bebas", yang menyatakan bahwa penuaan dan penyakit terkait dipicu oleh kerusakan radikal bebas pada makromolekul seluler dan ketidakmampuan sistem antioksidan endogen untuk mengatasi ...
Ari Tirtayasa, Made Jawi, Adiartha Griadhi   +2 more
openaire   +1 more source

The structural basis for the selective antagonism of soluble TNF-alpha by shark variable new antigen receptors

Nature Communications
The pro-inflammatory cytokine tumor necrosis factor-alpha (TNF-α) is synthesized as transmembrane TNF-α (tmTNF-α) where proteolytic processing releases soluble TNF-α (sTNF-α).
Obinna C. Ubah, Eric W. Lake, Kendahl L. Ott, Stella Priyanka, Sasha Celeda, Jayden L. West, Gihan S. Gunaratne, Ke Shi, Nicholas H. Moeller, Andrew J. Porter, Hideki Aihara, David Kosoff, Aaron M. LeBeau, Caroline J. Barelle   +13 more
doaj   +1 more source

Standardization and Comparison of an XTT-Based TNF-α Bioassay with a TNF-α ELISA

BioTechniques, 1998
Lloyd W. Turtinen, Brian D. Juran
doaj   +1 more source