Results 31 to 40 of about 3,516,666 (358)

Critical role of tumor necrosis factor-α in the early process of wound healing in skin

open access: yesJournal of Dermatology and Dermatologic Surgery, 2017
Tumor necrosis factor (TNF)-α is quickly released and initiates inflammation at wound tissues, but its precise role in wound healing is not fully understood.
Masae Ritsu   +7 more
doaj   +1 more source

Angiotensin II‐induced natriuresis is attenuated in knockout mice lacking the receptors for tumor necrosis factor‐α

open access: yesPhysiological Reports, 2021
Intravenous infusion of relatively higher doses of angiotensin II (AngII) elicits natriuresis as opposed to its usual anti‐natruretic response. As AngII can induce tumor necrosis factor‐α (TNFα) production which elicits natriuresis via its action on TNFα
Dewan S. A. Majid, Alexander Castillo
doaj   +1 more source

Complexity of TNF-α Signaling in Heart Disease

open access: yesJournal of Clinical Medicine, 2020
Heart disease is a leading cause of death with unmet clinical needs for targeted treatment options. Tumor necrosis factor alpha (TNF-α) represents a master pro-inflammatory cytokine that plays an important role in many immunopathogenic processes.
F. Rolski, P. Błyszczuk
semanticscholar   +1 more source

Pulmonary artery perfusion with anti-tumor necrosis factor alpha antibody reduces cardiopulmonary bypass-induced inflammatory lung injury in a rabbit model. [PDF]

open access: yesPLoS ONE, 2013
Inflammatory lung injury is one of the main complications associated with cardiopulmonary bypass (CPB). Tumor necrosis factor-α (TNF-α) is one of the key factors mediating the CPB-induced inflammatory reactions.
Yang Yu   +4 more
doaj   +1 more source

TNF-α levels and presence of SNP-308G/A of TNF-α gene in temporomandibular disorder patients

open access: yes, 2022
Introduction: Temporomandibular disorder (TMD) refers to a group of conditions that compromise the harmonious movement and function of the temporomandibular joint, masticatory muscles, and associated structures.
Renata Silva Melo FERNANDES (12853596)   +4 more
core   +1 more source

Activation of caspase-8 by tumour necrosis factor receptor 1 is necessary for caspase-3 activation and apoptosis in oxygen–glucose deprived cultured cortical cells

open access: yesNeurobiology of Disease, 2009
TNF-α has been reported to be relevant in stroke-induced neuronal death. However the precise function of TNF-α in brain ischemia remains controversial since there are data supporting either a detrimental or a protective effect. Here we show that TNF-α is
Nahuai Badiola   +6 more
doaj   +1 more source

TNF-α in Uveitis: From Bench to Clinic

open access: yesFrontiers in Pharmacology, 2021
Uveitis is an inflammation of the iris, ciliary body, vitreous, retina, or choroid, which has been shown to be the first manifestation of numerous systemic diseases.
Qi Jiang   +6 more
doaj   +1 more source

TNF‐α enhances TGF‐β‐induced endothelial‐to‐mesenchymal transition via TGF‐β signal augmentation

open access: yesCancer Science, 2020
The tumor microenvironment (TME) consists of various components including cancer cells, tumor vessels, cancer‐associated fibroblasts (CAFs), and inflammatory cells. These components interact with each other via various cytokines, which often induce tumor
Yasuhiro Yoshimatsu   +10 more
semanticscholar   +1 more source

TNF‐α polymorphisms affect persistence and progression of HBV infection

open access: yesMolecular Genetics & Genomic Medicine, 2019
Background Hepatitis B virus (HBV) infections are a major threat worldwide. Disease progression and outcome is diverse and depends on host genetic background. Recently, a high rate of HBV reactivation in individuals receiving tumor necrosis factor‐α (TNF‐
Anna Woziwodzka   +6 more
doaj   +1 more source

Regulatory T cells in Crohn's disease following anti‐TNF‐α therapy

open access: yesJGH Open, 2020
Background and Aim Anti‐tumor necrosis factor alpha (TNF‐α) therapy is an effective therapy for Crohn's disease (CD). We investigated FoxP3+ and CD127− regulatory T cells (Tregs) before and after administration of anti‐TNF‐α therapy in CD.
Toshimi Chiba   +6 more
doaj   +1 more source

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