Results 11 to 20 of about 1,383,229 (318)

Association between TNF-α polymorphisms and responsiveness to TNF-α blockers in ankylosing spondylitis and psoriatic arthritis: a meta-analysis [PDF]

Scientific Reports
To investigate the association between tumor necrosis factor-alpha (TNF-α) polymorphisms and the responsiveness to anti-TNF-α therapy in patients with ankylosing spondylitis (AS) and psoriatic arthritis (PsA).
Young Ho Lee, Gwan Gyu Song
doaj   +2 more sources

Assessment of IL6 and TNF α in Chronic Lymphocytic Leukemia [PDF]

International Journal of Medical Arts, 2022
Background: Among the cytokines and inflammatory markers, Interleukin 6 [IL6] and TNF α are the most common markers in the practice of medicine. Many studies determine the values of these two markers among the patients with chronic lymphocytic leukemia ...
Mohamed Abd-El-Haleem Mousa, Ibrahim ElSayed Eweis, Salem Ahmed, Abdullah Gaafar   +3 more
doaj   +1 more source

Study of TNF α gene polymorphism in Type 2 Diabetes [PDF]

Minia Journal of Medical Research, 2020
DM is one of the five principal causes of death universally. It is a growing heath problem of multifactorial origin, understanding its genetic background might help in early detection and disease prevention.
Sahar El-Hin, Amira Ahmed, Eglal Hamed, Yehia Mahmoud, Amel Eldin, Hend Abdelghany   +5 more
doaj   +1 more source

Assessment of Anti-TNF-α Activities in Keratinocytes Expressing Inducible TNF- α: A Novel Tool for Anti-TNF-α Drug Screening. [PDF]

PLoS ONE, 2016
Tumor necrosis factor alpha (TNF-α) is a pro-inflammatory cytokine important in normal and pathological biological processes. Newly synthesized pro-TNF-α is expressed on the plasma membrane and cleaved to release soluble TNF-α protein: both are ...
Sutthirat Udommethaporn, Tewin Tencomnao, Eileen M McGowan, Viroj Boonyaratanakornkit   +3 more
doaj   +1 more source

Anti-tumor necrosis factor-α is potentially better than tumor necrosis factor-α as the biomarker for sarcopenia: Results from the I-Lan longitudinal aging study

Experimental Gerontology, 2023
Tumor necrosis factor (TNF)-α is a proinflammatory cytokine involved in the pathogenesis of sarcopenia, but its short half-life and inconsistent reproducibility limit the potential of TNF-α to be an ideal sarcopenia biomarker.
Wei-Ju Lin, Wei-Ju Lee, Li-Ning Peng, Yi-Long Huang, Chien-Yi Tung, Chi-Hung Lin, Ting-Fen Tsai, Liang-Kung Chen   +7 more
doaj   +1 more source

Correlation of Serum Interleukin-6, TNF-α, Procalcitonin and Leukocyte Count in Patients with Suspected Sepsis [PDF]

INDONESIAN JOURNAL OF CLINICAL PATHOLOGY AND MEDICAL LABORATORY, 2020
Sepsis is a cause of non-cardiac death in the hospital. Early and rapid diagnosis of septic patients is a challenge toincrease the expectancy of life. IL-6 and TNF-α are groups of pro inflammatory cytokines that initiate an initial inflammatoryresponse. Procalcitonin is a specific marker of bacterial infection.
Erfina Lim, Jusak Nugraha
openaire   +1 more source

Tristetraprolin Down-Regulation Contributes to Persistent TNF-Alpha Expression Induced by Cigarette Smoke Extract through a Post-Transcriptional Mechanism. [PDF]

PLoS ONE, 2016
Tumor necrosis factor-alpha (TNF-α) is a potent pro-inflammatory mediator and its expression is up-regulated in chronic obstructive pulmonary disease (COPD).
Xue-Ke Zhao, Pulin Che, Ming-Liang Cheng, Quan Zhang, Mao Mu, Hong Li, Yuan Luo, Yue-Dong Liang, Xin-Hua Luo, Chang-Qing Gao, Patricia L Jackson, J Michael Wells, Yong Zhou, Meng Hu, Guoqiang Cai, Victor J Thannickal, Chad Steele, J Edwin Blalock, Xiaosi Han, Ching-Yi Chen, Qiang Ding   +20 more
doaj   +1 more source

Serum TGF-β and TNF-α During Psoriasis Therapy with Narrowband Ultraviolet B [PDF]

American Journal of Applied Sciences, 2014
Although it is now an accepted concept that narrow-band UVB therapy is an efficacious therapy for psoriasis, the relationship between the response rate and the potential effects on serum cytokines is less well-established. The purpose of this study was to investigate the correlation between the response rate and the changes of serum TGF-I² and TNF-I ...
Ahmad Taha Khalaf, Yan Yuehua
openaire   +1 more source

The correlation TNF-α gene promoter region -238G, -308G, -857, and -1031 polymorphism with psoriasis vulgaris

Bali Medical Journal, 2021
Background: Psoriasis vulgaris is a recurrent chronic skin disorder signed by hyperproliferation and epidermal inflammation. One of the etiology of psoriasis is genetic factors related to genetic polymorphism as disease susceptibility markers. This study was aimed to analyze the correlation of TNF-α gene promoter region polymorphism with psoriasis ...
Cashtri Meher, R. Lia Kusumawati Iswara, Irma D Roesyanto-Mahadi   +2 more
openaire   +1 more source

TNF-α evokes blood-brain barrier dysfunction through activation of Rho-kinase and neurokinin 1 receptor

, 2023
Ischaemic stroke, accompanied by neuroinflammation, impairs blood–brain barrier (BBB) integrity through a complex mechanism involving activation of both RhoA/Rho kinase/myosin light chain-2 and neurokinin 1 receptor (NK1R).
Gao, Xin, Ulvi Bayraktutan, Xin Gao, Bayraktutan, Ulvi   +3 more
core   +1 more source