Results 41 to 50 of about 820,645 (209)

Angiotensin II‐induced natriuresis is attenuated in knockout mice lacking the receptors for tumor necrosis factor‐α

Physiological Reports, 2021
Intravenous infusion of relatively higher doses of angiotensin II (AngII) elicits natriuresis as opposed to its usual anti‐natruretic response. As AngII can induce tumor necrosis factor‐α (TNFα) production which elicits natriuresis via its action on TNFα
Dewan S. A. Majid, Alexander Castillo
doaj   +1 more source

Macrophage TNF-α mediates parathion-induced airway hyperreactivity in guinea pigs. [PDF]

, 2013
Organophosphorus pesticides (OPs) are implicated in human asthma. We previously demonstrated that, at concentrations that do not inhibit acetylcholinesterase activity, the OP parathion causes airway hyperreactivity in guinea pigs as a result of ...
Allison D. Fryer, Becky J. Proskocil, Borish L, Crain EF, Crinnion WJ, David B. Jacoby, Donald A. Bruun, Gallo MA, Grodzki AC, Lu C, Nico van Rooijen, Pamela J. Lein, Rozyk KJ   +12 more
core   +1 more source

Regulatory T cells in Crohn's disease following anti‐TNF‐α therapy

JGH Open, 2020
Background and Aim Anti‐tumor necrosis factor alpha (TNF‐α) therapy is an effective therapy for Crohn's disease (CD). We investigated FoxP3+ and CD127− regulatory T cells (Tregs) before and after administration of anti‐TNF‐α therapy in CD.
Toshimi Chiba, Mikiya Endo, Shoko Miura, Yuko Hayashi, Yoshiko Asakura, Kotaro Oyama, Takayuki Matsumoto   +6 more
doaj   +1 more source

Human Bocavirus NS1 and NS1-70 Proteins Inhibit TNF-α-Mediated Activation of NF-κB by targeting p65. [PDF]

, 2016
Human bocavirus (HBoV), a parvovirus, is a single-stranded DNA etiologic agent causing lower respiratory tract infections in young children worldwide.
A Christensen, A Zhou, AY Chen, B Huang, ET Martin, F Mercurio, H Lukkarinen, HL Luo, J Hiscott, J Napetschnig, J Shen, KA Park, L Unterholzner, L Verstrepen, LF Chen, M Coiras, M Meriluoto, M Severa, MG Santoro, MS Hayden, N Edner, ND Perkins, Q Huang, R Dijkman, RE Randall, RN Silk, RW Korner, S Ghosh, SF Cotmore, T Allander, T Allander, T Lu, T Ursic, TD Gilmore, TE Morrison, W Shen, X Li, XF Deng, Y Hirose, Z Zheng, ZF Zhang   +40 more
core   +1 more source

Peran Magnesium Sulfat dalam Menurunkan Kadar TNF-α dan IL-1β pada Bayi Prematur

Jurnal Kedokteran Brawijaya, 2017
Prematuritas menyebabkan mortalitas dan morbiditas neonatus yaitu cerebral palsy (CP), gangguan kognitif dan gangguan tingkah laku. Sitokin proinflamasi TNF-α dan IL-1β diduga secara signifikan meningkat pada bayi prematur. Magnesium sulfat (MgSO4) diduga dapat sebagai neuroprotektor terhadap otak janin, melindungi jaringan terhadap aktivitas radikal
Sri Sulistyowati, Ferri Waluyo Wiwoho Pujojati, Supriyadi Hari Respati, Soetrisno - -   +3 more
openaire   +2 more sources

Penurunan Luaran Neurodevelopmental pada Sepsis Neonatal terjadi melalui Peningkatan IL- 6 dan bukan TNF-α

Jurnal Kedokteran Brawijaya, 2015
Bayi yang mengalami gangguan pada masa prenatal, natal dan paska natal mempunyai risiko tinggi untuk mendapatkan hambatan tumbuh kembang secara optimal dibandingkan bayi lainnya. IL-6 dan TNF-α merupakan salah satu sitokin yang diproduksi saat terjadi sepsis dan mempunyai peranan pada perkembangan otak sebagai sinyal proinflamasi.
Rahmawati Aminingrum, Ariani Ariani, M Istiadjid ES   +2 more
openaire   +2 more sources

Ex vivo innate immune cytokine signature of enhanced risk of relapsing brucellosis. [PDF]

, 2013
BackgroundBrucellosis, a zoonotic infection caused by one of the Gram-negative intracellular bacteria of the Brucella genus, is an ongoing public health problem in Perú.
Feldman, Kristyn E, Gilman, Robert H, Gotuzzo, Eduardo, Hoffmann, Alexander, Loriaux, Paul M, Saito, Mayuko, Siva, Tenaya, Tuero, Iskra, Villaverde, Homarh, Vinetz, Joseph M   +9 more
core   +3 more sources

The inflammatory cytokine tumor necrosis factor modulates the expression of Salmonella typhimurium effector proteins

Journal of Inflammation, 2010
Tumor necrosis factor α (TNF-α)is a host inflammatory factor. Bacteria increase TNF-α expression in a variety of human diseases including infectious diseases, inflammatory bowel diseases, and cancer.
Ma Jun, Zhang Yong-guo, Xia Yinglin, Sun Jun   +3 more
doaj   +1 more source

TNF-α in Uveitis: From Bench to Clinic

Frontiers in Pharmacology, 2021
Uveitis is an inflammation of the iris, ciliary body, vitreous, retina, or choroid, which has been shown to be the first manifestation of numerous systemic diseases.
Qi Jiang, Zhaohuai Li, Tianyu Tao, Runping Duan, Xianggui Wang, Xianggui Wang, Wenru Su   +6 more
doaj   +1 more source

Korelasi Kadar Vitamin D, dengan TNF-α dan Manifestasi Klinis pada Pasien Artritis Rematoid

Jurnal Kedokteran Brawijaya, 2014
Artritis rematoid (AR) adalah penyakit autoimun yang ditandai dengan sinovitis erosif simetrik, diawali dengan  aktivasi sel T dependent antigen yang akan mencetuskan respon imun, terutama tipe Th1. Tumor necrosis factor (TNF-α) adalah sitokin sentral pada patogenesis AR.  Diketahui bahwa defisiensi vitamin D berkaitan dengan eksaserbasi respon imun
Hanik Ruliani, Handono Kalim, BP Putra Suryana, Kusworini Handono   +3 more
openaire   +2 more sources