Results 61 to 70 of about 3,516,666 (358)
TNF-αは、アポトーシスを誘導することでLegionella pneumophilaの気道上皮細胞内での増殖を抑制する [PDF]
, 2017 Background: TNF-α plays an important role in the pathogenesis of Legionella pneumophila (Lp)-induced pneumonia. Patients undergoing anti-TNF-α therapy are at an increased risk of Lp infection.
川元, 康嗣
core +1 more source
TNF-α Directly Enhances Osteocyte RANKL Expression and Promotes Osteoclast Formation
Frontiers in Immunology, 2019 Osteoimmunology peeks into the interaction of bone and the immune system, which has largely proved to be a multiplex reaction. Osteocytes have been shown to regulate bone resorption through the expression of RANKL in physiologic and pathologic conditions.
A. Marahleh +9 more
semanticscholar +1 more source
Peran Magnesium Sulfat dalam Menurunkan Kadar TNF-α dan IL-1β pada Bayi Prematur
Jurnal Kedokteran Brawijaya, 2017 Prematuritas menyebabkan mortalitas dan morbiditas neonatus yaitu cerebral palsy (CP), gangguan kognitif dan gangguan tingkah laku. Sitokin proinflamasi TNF-α dan IL-1β diduga secara signifikan meningkat pada bayi prematur. Magnesium sulfat (MgSO4) diduga dapat sebagai neuroprotektor terhadap otak janin, melindungi jaringan terhadap aktivitas radikal
Sri Sulistyowati +3 more
openaire +2 more sources
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
TNF-α production in response to LPS.
, 2016 (A) Comparison of basal levels of TNFA mRNA in granulocytes among healthy controls, Group A and Group B. (B) Comparison of fold increase of TNFA mRNA induced by simulation with 1 μg/mL LPS for indicated times.
Hideo Kimura (402027) +10 more
core +1 more source
Modulation of autocrine TNF-α-stimulated matrix metalloproteinase 9 (MMP-9) expression by mitogenactivated protein kinases in THP-1 monocytic cells [PDF]
, 2006 Matrix metalloproteinase 9 (MMP-9) is implicated in various physiological processes by its ability to degrade the extracellular matrix (ECM) and process multiple regulatory proteins. Normally, MMP-9 expression is tightly controlled in cells. Sustained or
Helmut Kolb +9 more
core +1 more source
Indonesia Journal of Biomedical Science, 2012 Lifestyle changes to consumption of variegated instant food may be associated several heath hazards, such as obesity, dyslipidemia, and atheroschlerosis. This study was conducted to investigate the effects of orally administered Sardinella longiceps oil as an anti inflammatory agent on the serum levels of TNF-α and IL-6 considered as biomarkers for ...
S. Wahjuni +3 more
openaire +1 more source
Development of hematogenous pneumococcal meningitis in adult mice: the role of TNF-α [PDF]
FEMS Immunology & Medical Microbiology, 2002 Bacterial penetration across the blood-brain barrier (BBB) into the central nervous system is the first step in development of meningitis. The role of tumor necrosis factor-alpha (TNF-alpha) in the penetration process was examined with peripheral infection of Streptococcus pneumoniae type 6. After intraperitoneal infection of S.
N, Tsao, W W, Chang, C C, Liu, H Y, Lei
openaire +2 more sources
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
TNF-α-stimulated NF-κB activation assay.
, 2018 (A) and (B) Measurement of bioluminescence from cells without or with TNF-αstimulation. Monoclonal HeLa cells stably transfected with the NF-κB-secNluc-FLAG gene were inoculated at different densities (0 to 8000 cells per well) in 24-well plates for 12 h.
Dan Qian (343850) +12 more
core +1 more source