Results 51 to 60 of about 820,645 (209)

TNF-α and Interleukin-6 Levels in Clinical Early Onset Neonatal Sepsis Toward Acute Liver Injury

Jurnal Kedokteran Brawijaya, 2016
TNF-α and IL-6 level have an important role in acute liver injury during early onset neonatal sepsis. This study aims to investigate the correlation of TNF-α and IL-6 levels in neonates with clinical early onset neonatal sepsis toward the occurrence of acute liver injury 44 neonates with clinical early onset neonatal sepsis based on SIRS criteria and
Diani Dinarshanty, Noorhamdani AS, Siti Lintang Kawuryan, Satrio Wibowo   +3 more
openaire   +1 more source

Peptide-Based Regulation of TNF-α-Mediated Cytotoxicity

Biomolecules
Tumor necrosis factor alpha (TNF-α) is a pro-inflammatory cytokine associated with TNF receptor 1 (TNFR1) and TNF receptor 2 (TNFR2), which play important roles in several inflammatory diseases.
Betul Zehra Temur, Ahmet Can Timucin, Ahmet Emin Atik, Tanil Kocagoz, Ozge Can   +4 more
doaj   +1 more source

Establishment of a consistent L929 bioassay system for TNF-α quantitation to evaluate the effect of lipopolysaccharide, phytomitogens and cytodifferentiation agents on cytotoxicity of TNF-α secreted by adherent human mononuclear cells

Mediators of Inflammation, 2001
Tumor necrosis factor-α (TNF-α ) plays an important role in the pathogenesis of rheumatoid arthritis. The present study was to evaluate the effects of lipopolysaccharide (LPS), phytomitogens and cytodifferentiation agents on cytotoxicity of TNF-α ...
Ming-Yuh Shiau, Hui-Ling Chiou, Yao-Ling Lee, Tzer-Min Kuo, Yih-Hsin Chang   +4 more
doaj   +1 more source

Prospective assessment of body weight and body composition changes in patients with psoriasis receiving anti-TNF-α treatment [PDF]

, 2011
Tumor necrosis factor (TNF)-α is a pro-inflammatory cytokine associated with psoriasis pathogenesis. Anti-TNF-α therapies are effective in psoriasis. A significant weight gain has been reported in patients treated with anti-TNF-α agents.
Bianchi, A, Chimenti, S, DE Lorenzo, A, Di Renzo, L, Esposito, M, Noce, A, Rizzo, M, Saraceno, R, Schipani, C, Tiberti, S   +9 more
core   +1 more source

Injeksi Serum Mengandung TNF-α Tinggi Menurunkan Konsentrasi VEGF dan Ekspresi Nephrin Glomerulus Mencit Bunting

Jurnal Kedokteran Brawijaya, 2016
Preeklampsia ditandai dengan adanya hipertensi dan proteinuria pada usia kehamilan lebih dari 20 minggu. Preeklampsia diderita oleh 3%-8% wanita hamil dan menjadi penyebab utama kematian pada kehamilan. Tumor Necrosis Factor-α(TNF-α) diduga memiliki peranan penting dalam menimbulkan terjadinya preeklampsia.
Syahroni Yudistian Agmar, Siti Candra Windu Batiyani, Loeki E Fitri   +2 more
openaire   +1 more source

The TNF-α-308G/A Gene Polymorphism and Serum TNF-α Levels in Women With Preeclampsia

Journal of Family and Reproductive Health, 2022
Objective: Worldwide, preeclampsia (PE) is a multifactorial disorder reported in 2–5% of pregnancies, which increases mortality during pregnancy. In general, 10–15% of maternal deaths are directly related to PE and eclampsia.
Allahdad Khodadadi, Ata Ghadiri, Mehri Ghafourian, Sara Iranparast, Mahin Najafian   +4 more
doaj   +1 more source

TNF-α gene polymorphisms: association with age-related macular degeneration in Russian population [PDF]

International Journal of Ophthalmology, 2019
AIM: To study polymorphisms in promotor regions of tumor necrosis factor (TNF)-α TNF-863A/C (rs1800630), TNF-308A/G (rs1800629), and TNF-238A/G (rs361525) in patients with age-related macular degeneration (AMD) and associations of complex TNF-α genotypes
Valeriy Chernykh, Alla Shevchenko, Vladimir Konenkov, Viktor Prokofiev, Alena Eremina, Alexander Trunov   +5 more
doaj   +1 more source

Extracellular vesicles in osteoarthritis synovial fluid contain both transmembrane and intravesical TNF-α

Osteoarthritis and Cartilage Open
Objective: We previously identified extracellular vesicles (EVs) as a key source of TNF-α in the plasma of both knee osteoarthritis (OA) patients and healthy individuals.
Xin Zhang, Virginia Byers Kraus
doaj   +1 more source

Development of monoclonal antibodies for quantification of bovine tumor necrosis factor-α

JDS Communications, 2021
The expression of the proinflammatory cytokine tumor necrosis factor-α (TNF-α) is associated with production losses in dairy cows and is a hallmark of early inflammatory processes. Reliable tools for the detection and quantification of soluble as well as
Anja Sipka, Susanna Babasyan, Sabine Mann, Heather Freer, Suzanne Klaessig, Bettina Wagner   +5 more
doaj   +1 more source

Effect of Artemisia fruit extract on TNF- α and IL-6 levels in streptozotocin-induced diabetic mice

Journal of Contemporary Medical Sciences, 2019
Objective: The present study was conducted to investigate the effects of Artemisia extract on some immunological parameters in streptozotocin-induced diabetic mice. Methods: After preparation of Artemisia extract, many chemical tests were used to identify the type of element and compounds presented in this plant using many chemical techniques ...
Ekhlass N. Ali, Emad Mahmoud Eltyeaf, Ashwaq A. Kadhem, Jamela Jouda   +3 more
openaire   +2 more sources