Results 1 to 10 of about 1,176,895 (316)

Virus encoded cytokines and cytokine receptors

Parasitology, 1997
In order to replicate efficiently within the host, viruses have evolved multiple strategies to evade the host's immune system. In many cases viruses have actually hijacked various components of the host's immune system to ensure their own survival. One such strategy is the expression of virus encoded cytokines and cytokine receptors. Members of
M, Barry, G, McFadden
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Longitudinal, natural history study reveals the disease burden of idiopathic multicentric Castleman disease

Haematologica
Idiopathic multicentric Castleman disease (iMCD) is a rare hematologic disorder with heterogeneous presentations ranging from moderate constitutional symptoms to life-threatening multiorgan system involvement. iMCD patients present with vastly different
Mateo Sarmiento Bustamante, Sheila K. Pierson, Yue Ren, Adam Bagg, Joshua D. Brandstadter, Gordan Srkalovic, Natalie Mango, Daisy Alapat, Mary Jo Lechowicz, Hongzhe Li, Frits van Rhee, Megan S. Lim, David C. Fajgenbaum   +12 more
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SnapShot: Cytokines I

Cell, 2008
IL17RA or IL17RCTh17 cells and others Mucosal tissues, epithelial and endothelial cells Proinflammatory; protective immunity in lung; tight junction integrity; promotes mobilization of neutrophils and cytokine production by epithelial cells; promotes angiogenesis↓ = susceptibility to extracellular pathogens↑ = exacerbates organ-specific autoimmune ...
Tato, Cristina M., Cua, Daniel J.
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Common connective tissue disorder and anti-cytokine autoantibodies are enriched in idiopathic multicentric castleman disease patients

Frontiers in Immunology
IntroductionIdiopathic Multicentric Castleman Disease (iMCD) is a polyclonal lymphoproliferative disorder involving cytokine storms that can lead to organ failure and death.
Allan Feng, Allan Feng, Michael V. Gonzalez, Muge Kalaycioglu, Muge Kalaycioglu, Xihui Yin, Xihui Yin, Melanie Mumau, Saishravan Shyamsundar, Mateo Sarmiento Bustamante, Sarah E. Chang, Sarah E. Chang, Shaurya Dhingra, Shaurya Dhingra, Tea Dodig-Crnkovic, Jochen M. Schwenk, Tarun Garg, Kazuyuki Yoshizaki, Frits van Rhee, David C. Fajgenbaum, Paul J. Utz, Paul J. Utz   +21 more
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Cytokines and proteoglycans [PDF]

Experientia, 1993
Cytokines play an important regulatory role in the metabolism of proteoglycans. Proteoglycans are found in plasma membranes, but predominantly in the extra-cellular matrix. In the latter they are quantitatively and qualitatively essential components. Especially in a tissue like cartilage without any blood vessels, the cells are dependent on cytokines ...
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Bacterial peptidoglycan levels have brain area, time of day, and sleep loss-induced fluctuations

Frontiers in Neuroscience
Sleep-inducing bacterial cell wall components isolated from brain and urine of sleep deprived animals were identified as peptidoglycan (PG) and muropeptides in the 1980s.
Erika L. English, James M. Krueger
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Coxsackie B1 virus-like particle vaccine modified to exclude a highly conserved immunoreactive region from the capsid induces potent neutralizing antibodies and protects against infection in mice

Journal of Biomedical Science
Background Enteroviruses, including Coxsackie B (CVB) viruses, can cause severe diseases such as myocarditis, pancreatitis, and meningitis. Vaccines can prevent these complications, but conserved non-neutralizing epitopes in the viral capsid may limit ...
Saana Soppela, Martín González-Rodríguez, Virginia M. Stone, Iiris Mustonen, Niila V. V. Jouppila, Vili Lampinen, Teemu Haikarainen, Malin Flodström-Tullberg, Ilkka S. Junttila, Minna M. Hankaniemi   +9 more
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Peripheral blood inflammatory score using a cytokine multiplex assay predicts clinical outcomes in patients treated with atezolizumab-bevacizumab for unresectable HCC

Frontiers in Immunology
BackgroundSeveral serum cytokines have been proposed as biomarkers for predicting the outcomes of patients with hepatocellular carcinoma (HCC) receiving tyrosine kinase inhibitors. However, their role in atezolizumab plus bevacizumab (AB) treatment needs
Hee Sun Cho, Hee Sun Cho, Hee Sun Cho, Soon Kyu Lee, Soon Kyu Lee, Ji Won Han, Ji Won Han, Jung Hyun Kwon, Jung Hyun Kwon, Soon Woo Nam, Soon Woo Nam, Jaejun Lee, Jaejun Lee, Keungmo Yang, Keungmo Yang, Pil Soo Sung, Pil Soo Sung, Jeong Won Jang, Jeong Won Jang, Seung Kew Yoon, Seung Kew Yoon, Jong Young Choi, Jong Young Choi   +22 more
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Predictive survival modelings for HIV-related cryptococcosis: comparing machine learning approaches

Frontiers in Cellular and Infection Microbiology
IntroductionHIV-associated cryptococcosis is marked by unpredictable disease trajectories and persistently high mortality rates worldwide. Although improved risk stratification and tailored clinical management are urgently needed to enhance patient ...
Xuemin Fu, Luling Wu, Luling Wu, Jingna Xun, Benno Pütz, Zhihang Zheng, Yanpeng Li, Yanpeng Li, Yinzhong Shen, Hongzhou Lu, Jun Chen, Bertram Müller-Myhsok   +11 more
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Effect and clinical mechanism exploration of acupuncture intervention for chemotherapy-related cognitive impairment (CRCI) in triple-negative breast cancer: study protocol for a randomized controlled trial

Frontiers in Neurology
BackgroundChemotherapy-Related Cognitive Impairment (CRCI) significantly impacts the quality of life of breast cancer patients. Triple-negative breast cancer (TNBC) is associated with a higher risk of cognitive decline.
Wenqi Yang, Wenqi Yang, Qing Zhang, Chong Gao, Jingzhi Zhang, Jingzhi Zhang, Xingwei Guo, Xingwei Guo, Xin Liu, Xin Liu   +9 more
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