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Comparison of Serum Interleukin 10 Levels between Leprosy and Non-Leprosy Population
Mutiara Medika, 2021 Leprosy is a chronic granulomatous infectious disease that attacks the peripheral nerves, skin, and other organs. The cytokine IL-10 can deactivate macrophages, inhibit IL-12 production, which also inhibits IFN-ϒ production. IL-10 directly inhibits CD4+T
Adika Kodrati, Eddy Mart Salim, Zen Hafy
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The perspectives of interleukin-10 in the pathogenesis and therapeutics of multiple myeloma
Tzu Chi Medical Journal, 2021 Multiple myeloma (MM) is typically featured by the increased levels of inflammatory cytokines in the neoplastic plasma cells (PCs) producing monoclonal immunoglobulin.
Cheng-Der Liu +2 more
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Journal of Inflammation, 2021 Background The differences between adults and children in inflammatory bowel disease (IBD) phenotype, severity, complications, co-morbidities, and response to the therapy resulted in the extraction of paediatric IBD.
Paulina Krawiec +2 more
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Serum levels of interleukin-10 and its receptor in the multiple myeloma type I patients [PDF]
Journal of Research in Applied and Basic Medical Sciences, 2023 Background & Aims: Multiple myeloma is a malignancy of plasma cells that is associated with high morbidity rate. Inflammation is a common feature in malignancy and plays a pivotal role in the cancer pathogenesis.
Mehdi Rajabzadeh +4 more
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Biology of interleukin-10 [PDF]
Cytokine & Growth Factor Reviews, 2010 Interleukin (IL)-10 is the most important cytokine with anti-inflammatory properties besides TGF-β and IL-35. It is produced by activated immune cells, in particular monocytes/macrophages and T cell subsets including Tr1, Treg, and Th1 cells. IL-10 acts through a transmembrane receptor complex, which is composed of IL-10R1 and IL-10R2, and regulates ...
Robert, Sabat +6 more
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Tzu Chi Medical Journal, 2020 Objective: Human interleukin-10 (IL-10) is a dimeric and pleiotropic cytokine that plays a crucial role in cellular immunoregulatory responses. As IL-10 binds to its receptors, IL-10Ra and IL-10Rb, it will suppress or induce the downstream cellular ...
Chun-Chun Chang +5 more
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Mapping of the interleukin‐10/interleukin‐10 receptor combining site [PDF]
Protein Science, 1998 AbstractThe discontinuous interleukin‐10(IL‐10)/interleukin‐10 receptor (IL‐10R) combining site was mapped using sets of overlapping peptides derived from both binding partners bound to continuous cellulose membranes. Low affinity binding of single regions of the discontinuous contact sites on IL‐10 and IL‐10R could be identified due to (1) high ...
U, Reineke +3 more
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Role of interleukin 1β and interleukin 10 variants on ocular toxoplasmosis in Brazilian individuals
Frontiers in Ophthalmology, 2023 IntroductionOcular toxoplasmosis (OT) is an intraocular inflammation caused by Toxoplasma gondii infection that affects the retina and choroid, giving rise to posterior uveitis.
Warlen Miiller Rocha Araujo +12 more
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IDENTIFICATION OF -2849 IL-10 GENE PROMOTER POLYMORPHISM IN LEPROSY PATIENT
Jurnal Kedokteran dan Kesehatan, 2022 Leprosy is a chronic granulomatous disease. Leprosy is caused by M. leprae. However, not all exposure to M. leprae causes the disease. The condition of the host immune system determines the pathogenesis of leprosy.
Desi Oktariana +2 more
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Correlation Between Interleukin 6 and Interleukin 10 in Acute Myocardial Infarction
Biomolecules & Biomedicine, 2009 The aim of this study was to analyze (i) ratios between pro-inflammatory cytokines interleukin 6 (IL-6), interleukin 1 (IL-1), tumour necrosis factor α (TNF-α) and anti-inflammatory cytokine interleukin 10 (IL-10) in patients with acute myocardial ...
Larisa Dizdarević-Hudić +9 more
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