Results 1 to 10 of about 366,691 (317)

Neuronal synapse formation induced by microglia and interleukin 10. [PDF]

PLoS ONE, 2013
Recently, it was found that microglia regulated synaptic remodeling of the developing brain, but their mechanisms have not been well understood. In this study, the action of microglia on neuronal synapse formation was investigated, and the primary target
So-Hee Lim, Eunha Park, Boram You, Youngseob Jung, A-Reum Park, Sung Goo Park, Jae-Ran Lee   +6 more
doaj   +5 more sources

In Situ Identification of Both IL-4 and IL-10 Cytokine–Receptor Interactions during Tissue Regeneration

Cells, 2023
Cytokines secreted by individual immune cells regulate tissue regeneration and allow communication between various cell types. Cytokines bind to cognate receptors and trigger the healing process.
Krisztina Nikovics, Anne-Laure Favier, Mathilde Rocher, Céline Mayinga, Johanna Gomez, Frédérique Dufour-Gaume, Diane Riccobono   +6 more
doaj   +1 more source

Interleukin 10 and interleukin 10 receptor in paediatric inflammatory bowel disease: from bench to bedside lesson [PDF]

Journal of Inflammation, 2021
Abstract Background The differences between adults and children in inflammatory bowel disease (IBD) phenotype, severity, complications, co-morbidities, and response to the therapy resulted in the extraction of paediatric IBD.
Paulina Krawiec, Agnieszka Pawłowska-Kamieniak, Elżbieta Pac-Kożuchowska   +2 more
openaire   +3 more sources

Mapping of the interleukin‐10/interleukin‐10 receptor combining site [PDF]

Protein Science, 1998
AbstractThe discontinuous interleukin‐10(IL‐10)/interleukin‐10 receptor (IL‐10R) combining site was mapped using sets of overlapping peptides derived from both binding partners bound to continuous cellulose membranes. Low affinity binding of single regions of the discontinuous contact sites on IL‐10 and IL‐10R could be identified due to (1) high ...
U, Reineke, R, Sabat, H D, Volk, J, Schneider-Mergener   +3 more
openaire   +2 more sources

Evidence for Monocyte Reprogramming in a Long-Term Postsepsis Study

Critical Care Explorations, 2022
OBJECTIVES:. This study sought to identify monocyte alterations from septic patients after hospital discharge by evaluating gene expression of inflammatory mediators and monocyte polarization markers.
Raquel Bragante Gritte, PhD, Talita Souza-Siqueira, PhD, Eliane Borges da Silva, PhD, Laiane Cristina dos Santos de Oliveira, PhD, Rodrigo Cerqueira Borges, PhD, Heloísa H de Oliveira Alves, PhD, Laureane Nunes Masi, PhD, Gilson Masahiro Murata, PhD, Renata Gorjão, PhD, Adriana Cristina Levada-Pires, PhD, Antônio Carlos Nogueira, PhD, Tânia Cristina Pithon-Curi, PhD, Ricardo Bentes de Azevedo, PhD, Francisco Garcia Soriano, MD, PhD, Rui Curi, PhD, Marcel Cerqueira Cesar Machado, MD, PhD   +15 more
doaj   +1 more source

Gene polymorphisms in Toll-like receptors, interleukin-10, and interleukin-10 receptor alpha and lymphoma risk [PDF]

Genes & Immunity, 2006
Interactions between environment and immune system play an essential role in the aetiology of immunopathologies, including lymphomas. Toll-like receptors (TLR) belong to a group of pattern recognition receptors, with importance for innate immune response and inflammatory processes.
A, Nieters, L, Beckmann, E, Deeg, N, Becker   +3 more
openaire   +2 more sources

Escherichia coli–Specific CD4+ T Cells Have Public T-Cell Receptors and Low Interleukin 10 Production in Crohn’s DiseaseSummary

Cellular and Molecular Gastroenterology and Hepatology, 2020
Background & Aims: Crohn’s disease (CD) likely represents decreased immune tolerance to intestinal bacterial antigens. Most CD patients have high titers of antibodies to intestinal commensal proteins, including the outer membrane porin C (OmpC) of ...
Amiko M. Uchida, Elisa K. Boden, Eddie A. James, Donna M. Shows, Andrew J. Konecny, James D. Lord   +5 more
doaj   +1 more source

Involvement of suppressive B-lymphocytes in the mechanism of tolerogenic dendritic cell reversal of type 1 diabetes in NOD mice. [PDF]

PLoS ONE, 2014
The objective of the study was to identify immune cell populations, in addition to Foxp3+ T-regulatory cells, that participate in the mechanisms of action of tolerogenic dendritic cells shown to prevent and reverse type 1 diabetes in the Non-Obese ...
Valentina Di Caro, Brett Phillips, Carl Engman, Jo Harnaha, Massimo Trucco, Nick Giannoukakis   +5 more
doaj   +1 more source

Characterization of Endocannabinoid System and Interleukin Profiles in Ovine AEC: Cannabinoid Receptors Type-1 and Type-2 as Key Effectors of Pro-Inflammatory Response

Cells, 2020
Amniotic epithelial cells (AEC) have been proposed as promising clinical candidates for regenerative medicine therapies due to their immunomodulatory capacity.
Luana Greco, Valentina Russo, Cinzia Rapino, Clara Di Germanio, Filomena Fezza, Nicola Bernabò, Paolo Berardinelli, Alessia Peserico, Domenico Fazio, Mauro Maccarrone, Mauro Mattioli, Barbara Barboni   +11 more
doaj   +1 more source

Systemic inflammation in patients with chronic obstructive pulmonary disease and obesity [PDF]

Терапевтический архив, 2020
Chronic obstructive pulmonary disease (COPD) is an important public health problem. According to various studies, the prevalence of obesity in patients with COPD is as high as 50%. Aim.
E. S. Ovsyannikov, S. N. Avdeev, A. V. Budnevsky   +2 more
doaj   +1 more source