Results 1 to 10 of about 495,989 (311)

In Situ Identification of Both IL-4 and IL-10 Cytokine–Receptor Interactions during Tissue Regeneration

Cells, 2023
Cytokines secreted by individual immune cells regulate tissue regeneration and allow communication between various cell types. Cytokines bind to cognate receptors and trigger the healing process.
Krisztina Nikovics, Anne-Laure Favier, Mathilde Rocher, Céline Mayinga, Johanna Gomez, Frédérique Dufour-Gaume, Diane Riccobono   +6 more
doaj   +1 more source

Neuronal synapse formation induced by microglia and interleukin 10. [PDF]

PLoS ONE, 2013
Recently, it was found that microglia regulated synaptic remodeling of the developing brain, but their mechanisms have not been well understood. In this study, the action of microglia on neuronal synapse formation was investigated, and the primary target
So-Hee Lim, Eunha Park, Boram You, Youngseob Jung, A-Reum Park, Sung Goo Park, Jae-Ran Lee   +6 more
doaj   +1 more source

Evidence for Monocyte Reprogramming in a Long-Term Postsepsis Study

Critical Care Explorations, 2022
OBJECTIVES:. This study sought to identify monocyte alterations from septic patients after hospital discharge by evaluating gene expression of inflammatory mediators and monocyte polarization markers.
Raquel Bragante Gritte, PhD, Talita Souza-Siqueira, PhD, Eliane Borges da Silva, PhD, Laiane Cristina dos Santos de Oliveira, PhD, Rodrigo Cerqueira Borges, PhD, Heloísa H de Oliveira Alves, PhD, Laureane Nunes Masi, PhD, Gilson Masahiro Murata, PhD, Renata Gorjão, PhD, Adriana Cristina Levada-Pires, PhD, Antônio Carlos Nogueira, PhD, Tânia Cristina Pithon-Curi, PhD, Ricardo Bentes de Azevedo, PhD, Francisco Garcia Soriano, MD, PhD, Rui Curi, PhD, Marcel Cerqueira Cesar Machado, MD, PhD   +15 more
doaj   +1 more source

Escherichia coli–Specific CD4+ T Cells Have Public T-Cell Receptors and Low Interleukin 10 Production in Crohn’s DiseaseSummary

Cellular and Molecular Gastroenterology and Hepatology, 2020
Background & Aims: Crohn’s disease (CD) likely represents decreased immune tolerance to intestinal bacterial antigens. Most CD patients have high titers of antibodies to intestinal commensal proteins, including the outer membrane porin C (OmpC) of ...
Amiko M. Uchida, Elisa K. Boden, Eddie A. James, Donna M. Shows, Andrew J. Konecny, James D. Lord   +5 more
doaj   +1 more source

Involvement of suppressive B-lymphocytes in the mechanism of tolerogenic dendritic cell reversal of type 1 diabetes in NOD mice. [PDF]

PLoS ONE, 2014
The objective of the study was to identify immune cell populations, in addition to Foxp3+ T-regulatory cells, that participate in the mechanisms of action of tolerogenic dendritic cells shown to prevent and reverse type 1 diabetes in the Non-Obese ...
Valentina Di Caro, Brett Phillips, Carl Engman, Jo Harnaha, Massimo Trucco, Nick Giannoukakis   +5 more
doaj   +1 more source

Characterization of Endocannabinoid System and Interleukin Profiles in Ovine AEC: Cannabinoid Receptors Type-1 and Type-2 as Key Effectors of Pro-Inflammatory Response

Cells, 2020
Amniotic epithelial cells (AEC) have been proposed as promising clinical candidates for regenerative medicine therapies due to their immunomodulatory capacity.
Luana Greco, Valentina Russo, Cinzia Rapino, Clara Di Germanio, Filomena Fezza, Nicola Bernabò, Paolo Berardinelli, Alessia Peserico, Domenico Fazio, Mauro Maccarrone, Mauro Mattioli, Barbara Barboni   +11 more
doaj   +1 more source

Systemic inflammation in patients with chronic obstructive pulmonary disease and obesity [PDF]

Терапевтический архив, 2020
Chronic obstructive pulmonary disease (COPD) is an important public health problem. According to various studies, the prevalence of obesity in patients with COPD is as high as 50%. Aim.
E. S. Ovsyannikov, S. N. Avdeev, A. V. Budnevsky   +2 more
doaj   +1 more source

Differences in innate cytokine responses between European and African children. [PDF]

PLoS ONE, 2014
Although differences in immunological responses between populations have been found in terms of vaccine efficacy, immune responses to infections and prevalence of chronic inflammatory diseases, the mechanisms responsible for these differences are not ...
Lucja A Labuda, Sanne E de Jong, Lynn Meurs, Abena S Amoah, Moustapha Mbow, Ulysse Ateba-Ngoa, Alwin J van der Ham, André C Knulst, Maria Yazdanbakhsh, Ayola A Adegnika   +9 more
doaj   +1 more source

Atopic march in pediatrics: genotype-associated mechanisms Part 1. Genotype-associated mechanisms of the atopic march in children

Zdorovʹe Rebenka, 2017
The review deals with the data of studies over last 10 years of populations of different countries on association of atopic diseases being the components of the atopic march in children (atopic eczema, allergic rhinitis, allergic rhinoconjunctivitis ...
V.O. Dytiatkovsky
doaj   +1 more source

Reduction of circulating cholesterol and apolipoprotein levels during sepsis [PDF]

, 1999
Sepsis with multiple organ failure is frequently associated with a substantial decrease of cholesterol levels. This decrease of cholesterol is strongly associated with mortality suggesting a direct relation between inflammatory conditions and altered ...
Alvarez C, Chajek-Shaul T, Engelmann H, Ettinger WH, Ettinger WH, Ettinger WH, Feingold KR, Feingold KR, Flegel WA, Gouni I, Graham A, Greenberg AS, Grove RI, Grunfeld C, Hubsch AP, Ishibashi S, Kipp HA, Moran CS, Netea MG, Pacelli F, Pak YK, Read TE, Semb H, Stopeck AT, Van Gameren MM, Weinstock C, Wilson DE, Yokoyama K   +27 more
core   +1 more source