Results 31 to 40 of about 495,989 (311)
A model of the ternary complex of interleukin-10 with its soluble receptors [PDF]
BMC Structural Biology, 2005 AbstractBackgroundInterleukin-10 (IL-10) is a cytokine whose main biological function is to suppress the immune response by induction of a signal(s) leading to inhibition of synthesis of a number of cytokines and their cellular receptors. Signal transduction is initiated upon formation of a ternary complex of IL-10 with two of its receptor chains, IL ...
Pletnev, Sergei +3 more
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Molecular Mechanisms of Depression: Perspectives on New Treatment Strategies
Cellular Physiology and Biochemistry, 2013 Depression is a multicausal disorder and has been associated with the risk to develop cancer, dementia, diabetes, epilepsy and stroke. As a metabolic disorder depression has been associated with obesity, diabetes, insulin sensitivity, neuropeptide Y ...
Undine E. Lang, Stefan Borgwardt
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Interleukin-10: A double-edged sword in breast cancer
Tzu Chi Medical Journal, 2021 Breast cancer (BC) is a frequently diagnosed cancer among women worldwide. Currently, BC can be divided into different subgroups according to the presence of the following hormone receptors: estrogen receptor, progesterone receptor, and human epidermal ...
Chun-Ming Chang +3 more
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Characterization and Potential Applications of Dog Natural Killer Cells in Cancer Immunotherapy. [PDF]
, 2019 Natural killer (NK) cells of the innate immune system are a key focus of research within the field of immuno-oncology based on their ability to recognize and eliminate malignant cells without prior sensitization or priming.
Canter, Robert J +2 more
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Post-ischaemic immunological response in the brain: targeting microglia in ischaemic stroke therapy [PDF]
, 2020 Microglia, the major endogenous immune cells of the central nervous system, mediate critical degenerative and regenerative responses in ischaemic stroke.
Chen, Ruoli +4 more
core +3 more sources
Polymorphisms of interleukin-10 and its receptor and lung function in COPD [PDF]
European Respiratory Journal, 2007 Interleukin (IL)-10 is a type-2 T-helper cell cytokine with a broad spectrum of anti-inflammatory actions. Inflammation plays an important role in the pathogenesis of chronic obstructive pulmonary disease. It was hypothesised that single nucleotide polymorphisms (SNPs) of the genes encoding IL-10 (IL10) and the α subunit of its receptor (IL10RA) are ...
J-Q, He +5 more
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Frontiers in ImmunologyThere is an urgent need for alternative therapies targeting human dendritic cells (DCs) that could reverse inflammatory syndromes in many autoimmune and inflammatory diseases and organ transplantations.
Lucille Lamendour +16 more
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BMC Research Notes, 2018 Objective Human amniotic epithelial cells (hAECs) are a novel source of stem cells and have immunomodulatory effects on both the innate and adoptive immune system.
Ramezan Ali Taheri +6 more
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Journal of Immunology Research, 2020 The leishmanin skin test (LST) is an in vivo technique commonly used to evaluate the Leishmania-specific cellular immune response in dogs. However, information regarding the local immune response in LST-positive reactions is scarce.
Laura Ordeix +3 more
doaj +1 more source
Poultry Science, 2019 Coccidiosis is a major gastrointestinal disease caused by several Eimeria species in floor raised chickens. Feeding an antibody to interleukin 10 (aIL-10) ameliorates the negative symptoms of coccidiosis in broilers, i.e., lack of weight gain, decreased feed conversion, and mortality.
Maria K, Arendt +2 more
openaire +2 more sources