Results 1 to 10 of about 314,213 (267)

IL17A and IL17RA gene polymorphisms in Fanconi anemia [PDF]

Brazilian Oral Research, 2023
Fanconi anemia is a rare autosomal recessive disease. In this disease, cytokine pathways can induce the bone marrow failure that is observed in individuals with Fanconi anemia.
Rafael Zancan MOBILE, Monalisa Castilho MENDES, Cleber MACHADO-SOUZA, Priscila de Mattos QUEIROZ, Carmem Maria Sales BONFIM, Cassius Carvalho TORRES-PEREIRA, Juliana Lucena SCHUSSEL   +6 more
doaj   +1 more source

In Situ Identification of Both IL-4 and IL-10 Cytokine–Receptor Interactions during Tissue Regeneration

Cells, 2023
Cytokines secreted by individual immune cells regulate tissue regeneration and allow communication between various cell types. Cytokines bind to cognate receptors and trigger the healing process.
Krisztina Nikovics, Anne-Laure Favier, Mathilde Rocher, Céline Mayinga, Johanna Gomez, Frédérique Dufour-Gaume, Diane Riccobono   +6 more
doaj   +1 more source

Neuronal synapse formation induced by microglia and interleukin 10. [PDF]

PLoS ONE, 2013
Recently, it was found that microglia regulated synaptic remodeling of the developing brain, but their mechanisms have not been well understood. In this study, the action of microglia on neuronal synapse formation was investigated, and the primary target
So-Hee Lim, Eunha Park, Boram You, Youngseob Jung, A-Reum Park, Sung Goo Park, Jae-Ran Lee   +6 more
doaj   +1 more source

Relationship of Soluble Interleukin-6 Receptors With Asthma: A Mendelian Randomization Study

Frontiers in Medicine, 2021
Purpose: Emerging evidence suggests a potential role of interleukin-6 pathways—trans-signaling with soluble interleukin-6 receptors—in the asthma pathobiology.
Yoshihiko Raita, Zhaozhong Zhu, Carlos A. Camargo, Robert J. Freishtat, Robert J. Freishtat, Robert J. Freishtat, Debby Ngo, Liming Liang, Liming Liang, Kohei Hasegawa   +9 more
doaj   +1 more source

Imprint of Initial Education and Loss of Ly49C/I in Activated Natural Killer Cells of TAP1-KO and C57BL/6 Wildtype Mice

Frontiers in Immunology, 2022
Natural killer (NK) cells are important effectors of the innate immune system and participate in the first line of defense against infections and tumors.
Neha D. Patil, Neha D. Patil, Olivia Domingues, Cécile Masquelier, Maud Theresine, Oceane Schlienger, Clinton Njinju Amin Asaba, Marine Thomas, Carole Seguin-Devaux, Hortense Slevogt, Markus Ollert, Markus Ollert, Jacques Zimmer   +12 more
doaj   +1 more source

Gene-Edited Interleukin CAR-T Cells Therapy in the Treatment of Malignancies: Present and Future

Frontiers in Immunology, 2021
In recent years, chimeric antigen receptor T cells (CAR-T cells) have been faced with the problems of weak proliferation and poor persistence in the treatment of some malignancies.
Zhengchao Zhang, Zhengchao Zhang, Lele Miao, Lele Miao, Zhijian Ren, Zhijian Ren, Futian Tang, Futian Tang, Yumin Li, Yumin Li   +9 more
doaj   +1 more source

Genetic Deletion of mGlu3 Metabotropic Glutamate Receptors Amplifies Ischemic Brain Damage and Associated Neuroinflammation in Mice

Frontiers in Neurology, 2021
Backgroud: Type-3 metabotropic glutamate (mGlu3) receptors are found in both neurons and glial cells and regulate synaptic transmission, astrocyte function, and microglial reactivity.
Federica Mastroiacovo, Manuela Zinni, Giada Mascio, Valeria Bruno, Valeria Bruno, Giuseppe Battaglia, Giuseppe Battaglia, Julien Pansiot, Tiziana Imbriglio, Jerome Mairesse, Jerome Mairesse, Olivier Baud, Olivier Baud, Olivier Baud, Ferdinando Nicoletti, Ferdinando Nicoletti   +15 more
doaj   +1 more source

Presence of interleukin-8 and the IL-1 receptor antagonist in the cervical mucus of fertile and infertile women [PDF]

Vojnosanitetski Pregled, 2004
Background. Cytokines are involved in almost every aspect of reproduction and recent studies suggested a relationship between cytokines and male/female infertility.
Kataranovski Milena, Radojčić Ljiljana, Prokić Vera, Vojvodić Danilo   +3 more
doaj   +1 more source

Interleukin-2 Receptor γ Chain: a Functional Component of the Interleukin-7 Receptor [PDF]

Science, 1993
The interleukin-2 receptor γ chain (IL-2Rγ) is a necessary component of functional IL-2 receptors. IL-2Rγ mutations result in X-linked severe combined immunodeficiency (XSCID) in humans, a disease characterized by the presence of few or no T cells.
Noguchi, M., Nakamura, Y., Russell, S., Ziegler, S., Tsang, M., Cao, X., Leonard, W.   +6 more
openaire   +2 more sources

Interleukin-25 Produced by Synoviocytes Has Anti-inflammatory Effects by Acting As a Receptor Antagonist for Interleukin-17A Function

Frontiers in Immunology, 2017
The production and function of cytokines are highly regulated. One mechanism is the balance between pro- and anti-inflammatory cytokines. As interleukin (IL)-17A and IL-25 share the IL-17RA receptor chain, we hypothesize that IL-25 acts as an IL-17A ...
Fabien Lavocat, Ndiémé Ndongo-Thiam, Pierre Miossec   +2 more
doaj   +1 more source