Results 11 to 20 of about 314,213 (267)

Effects of CXCR1/2 Blockade with Ladarixin on Streptozotocin-Induced Type 1 Diabetes Mellitus and Peripheral Neuropathy and Retinopathy in Rat [PDF]

Diabetes & Metabolism Journal
Background The CXC motif chemokine ligand 8 (CXCL8)-CXC motif chemokine receptor 1/2 (CXCR1/2) axis has been implicated in type 1 diabetes mellitus (T1DM).
Serena Boccella, Andrea Maria Morace, Cristina Giorgio, Francesca Guida, Michela Perrone, Iolanda Manzo, Carmela Belardo, Meghan Jones, Sabatino Maione, Andrea Aramini, Marcello Allegretti, Livio Luongo, Laura Brandolini   +12 more
doaj   +1 more source

Soluble interleukin-2 receptors in ulcerative colitis

Mediators of Inflammation, 1993
T-Cell activation results in the release or shedding of a soluble form (45 kDa) of the cellular (55 kDa) low-affinity interleukin-2 receptor (α-chain) (slL-2R).
O. H. Nielsen, J. Brynskov
doaj   +1 more source

Expression of Interleukin-1 and Interleukin-1 Receptors Type 1 and Type 2 in Hodgkin Lymphoma. [PDF]

PLoS ONE, 2015
Signaling through the IL-1-receptor type 1 (IL-1R1), IL-1 is required for initiation and maintenance of diverse activities of the immune system. A second receptor, IL-1R2, blocks IL-1 signal transduction. We studied expression of IL-1beta, IL-1R1, and IL-
Elisabeth Oelmann, Harald Stein, Wolfgang E Berdel, Hermann Herbst   +3 more
doaj   +1 more source

Interleukin-1 in the Response of Follicular Helper and Follicular Regulatory T Cells

Frontiers in Immunology, 2019
The role of interleukin-1 in the regulation of humoral responses is poorly documented, in contrast to its role in inflammation. Recent findings suggest there is an interleukin-1 axis in the follicular T cell control of B cell responses, involving ...
Paul-Gydéon Ritvo, David Klatzmann, David Klatzmann   +2 more
doaj   +1 more source

Characterization of Endocannabinoid System and Interleukin Profiles in Ovine AEC: Cannabinoid Receptors Type-1 and Type-2 as Key Effectors of Pro-Inflammatory Response

Cells, 2020
Amniotic epithelial cells (AEC) have been proposed as promising clinical candidates for regenerative medicine therapies due to their immunomodulatory capacity.
Luana Greco, Valentina Russo, Cinzia Rapino, Clara Di Germanio, Filomena Fezza, Nicola Bernabò, Paolo Berardinelli, Alessia Peserico, Domenico Fazio, Mauro Maccarrone, Mauro Mattioli, Barbara Barboni   +11 more
doaj   +1 more source

Interleukin-17 Cytokines and Receptors: Potential Amplifiers of Tendon Inflammation

Frontiers in Bioengineering and Biotechnology, 2021
Interleukin (IL)-17A, a pro-inflammatory cytokine that is linked to the pathology of several inflammatory diseases, has been shown to be upregulated in early human tendinopathy and to mediate inflammatory and tissue remodelling events.
Jolet Y. Mimpen, Sarah J. B. Snelling, Andrew J. Carr, Stephanie G. Dakin   +3 more
doaj   +1 more source

Exploring causal associations between interleukins, their receptors, and acute respiratory distress syndrome: a bidirectional-Mendelian Randomization study

Frontiers in Genetics
BackgroundAcute Respiratory Distress Syndrome (ARDS) is a severe lung condition posing significant health risks. Observational studies have indicated a potential linkage between ARDS and various interleukins, such as Interleukin-8, −2, −6, and −1β ...
Jia-wei Ma, Jia-wei Ma, Ji-chun Tang, Hong-zhi Fang   +3 more
doaj   +1 more source

Suppression of interleukin-1 beta and LDL scavenger receptor expression in macrophages by a selective protein kinase C inhibitor.

Journal of Lipid Research, 1991
A human monocytic cell line, THP-1, stimulated with 40 nM phorbol myristate acetate (PMA), differentiated to macrophage-like cells, and exhibited increased expression and release of interleukin-1 beta and expression of acetylated low density lipoprotein (
AL Akeson, K Schroeder, C Woods, CJ Schmidt, W D Jones   +4 more
doaj   +1 more source

Interleukin-2 Receptor γ Chain: a Functional Component of the Interleukin-4 Receptor [PDF]

Science, 1993
The interleukin-2 (IL-2) receptor γ chain (IL-2Rγ) is an essential component of high- and intermediate-affinity IL-2 receptors. IL-2Rγ was demonstrated to be a component of the IL-4 receptor on the basis of chemical cross-linking data, the ability of IL-2Rγ to augment IL-4 binding affinity, and the requirement for IL-2Rγ in IL-4-mediated ...
Russell, S., Keegan, A., Harada, N., Nakamura, Y., Noguchi, M., Leland, P., Friedmann, M., Miyajima, A., Puri, R., Paul, W., Et, A.-L.   +10 more
openaire   +3 more sources

FEATURES OF THE RECEPTORS EXPRESSION FOR INTERLEUKIN 4 AND 5 IN THE FORMATION OF THE ATOPIC STATUS IN NEWBORNS

Педиатрическая фармакология, 2011
Identification of the early markers of the onset of atopic march in children remains important for the effective primary and secondary prevention of allergic diseases.
T.V. Turti, E.L. Semikina, L.S. Namazova-Baranova   +2 more
doaj   +2 more sources