Results 21 to 30 of about 511,016 (309)

Characterization of Endocannabinoid System and Interleukin Profiles in Ovine AEC: Cannabinoid Receptors Type-1 and Type-2 as Key Effectors of Pro-Inflammatory Response

Cells, 2020
Amniotic epithelial cells (AEC) have been proposed as promising clinical candidates for regenerative medicine therapies due to their immunomodulatory capacity.
Luana Greco, Valentina Russo, Cinzia Rapino, Clara Di Germanio, Filomena Fezza, Nicola Bernabò, Paolo Berardinelli, Alessia Peserico, Domenico Fazio, Mauro Maccarrone, Mauro Mattioli, Barbara Barboni   +11 more
doaj   +1 more source

The emerging role of IL‐38 in diseases: A comprehensive review

Immunity, Inflammation and Disease, 2023
Introduction Interleukin‐38 (IL‐38) is a new type of anti‐inflammatory cytokine, which is mainly expressed in the immunity‐related organs and is involved in various diseases including cardiovascular and cerebrovascular diseases, lung diseases, viral ...
Weijun Chen, Shuangyun Xi, Yong Ke, Yinlei Lei   +3 more
doaj   +1 more source

Interleukin-17 Cytokines and Receptors: Potential Amplifiers of Tendon Inflammation

Frontiers in Bioengineering and Biotechnology, 2021
Interleukin (IL)-17A, a pro-inflammatory cytokine that is linked to the pathology of several inflammatory diseases, has been shown to be upregulated in early human tendinopathy and to mediate inflammatory and tissue remodelling events.
Jolet Y. Mimpen, Sarah J. B. Snelling, Andrew J. Carr, Stephanie G. Dakin   +3 more
doaj   +1 more source

Exploring causal associations between interleukins, their receptors, and acute respiratory distress syndrome: a bidirectional-Mendelian Randomization study

Frontiers in Genetics
BackgroundAcute Respiratory Distress Syndrome (ARDS) is a severe lung condition posing significant health risks. Observational studies have indicated a potential linkage between ARDS and various interleukins, such as Interleukin-8, −2, −6, and −1β ...
Jia-wei Ma, Jia-wei Ma, Ji-chun Tang, Hong-zhi Fang   +3 more
doaj   +1 more source

Suppression of interleukin-1 beta and LDL scavenger receptor expression in macrophages by a selective protein kinase C inhibitor.

Journal of Lipid Research, 1991
A human monocytic cell line, THP-1, stimulated with 40 nM phorbol myristate acetate (PMA), differentiated to macrophage-like cells, and exhibited increased expression and release of interleukin-1 beta and expression of acetylated low density lipoprotein (
AL Akeson, K Schroeder, C Woods, CJ Schmidt, W D Jones   +4 more
doaj   +1 more source

FEATURES OF THE RECEPTORS EXPRESSION FOR INTERLEUKIN 4 AND 5 IN THE FORMATION OF THE ATOPIC STATUS IN NEWBORNS

Педиатрическая фармакология, 2011
Identification of the early markers of the onset of atopic march in children remains important for the effective primary and secondary prevention of allergic diseases.
T.V. Turti, E.L. Semikina, L.S. Namazova-Baranova   +2 more
doaj   +2 more sources

Memory Deficits Induced by Inflammation Are Regulated by α5-Subunit-Containing GABAA Receptors

Cell Reports, 2012
Systemic inflammation causes learning and memory deficits through mechanisms that remain poorly understood. Here, we studied the pathogenesis of memory loss associated with inflammation and found that we could reverse memory deficits by pharmacologically
Dian-Shi Wang, Agnieszka A. Zurek, Irene Lecker, Jieying Yu, Armen M. Abramian, Sinziana Avramescu, Paul A. Davies, Stephen J. Moss, Wei-Yang Lu, Beverley A. Orser   +9 more
doaj   +1 more source

In Silico Studies on Psilocybin Drug Derivatives Against SARS-CoV-2 and Cytokine Storm of Human Interleukin-6 Receptor

Frontiers in Immunology, 2022
Various metabolites identified with therapeutic mushrooms have been found from different sources and are known to have antibacterial, antiviral, and anticancer properties.
Faez Iqbal Khan, Fakhrul Hassan, Dakun Lai   +2 more
doaj   +1 more source

Interleukin-1 blockade in heart failure with preserved ejection fraction: rationale and design of the Diastolic Heart Failure Anakinra Response Trial 2 (D-HART2) [PDF]

, 2017
Heart failure with preserved ejection fraction (HFpEF) now accounts for the majority of con-firmed HF cases in the United States. However, there are no highly effective evidence-basedtreatments currently available for these patients.
Abbate, Antonio, Abouzaki, Nayef, Arena, Ross, Biondi-zoccai, Giuseppe, Buckley, Leo F., Canada, Justin M., Carbone, Salvatore, Dixon, Dave L., Oddi-erdle, Claudia, Trankle, Cory R., Van Tassell, Benjamin W.   +10 more
core   +1 more source

Interleukin-2 Receptor γ Chain: a Functional Component of the Interleukin-4 Receptor [PDF]

Science, 1993
The interleukin-2 (IL-2) receptor γ chain (IL-2Rγ) is an essential component of high- and intermediate-affinity IL-2 receptors. IL-2Rγ was demonstrated to be a component of the IL-4 receptor on the basis of chemical cross-linking data, the ability of IL-2Rγ to augment IL-4 binding affinity, and the requirement for IL-2Rγ in IL-4-mediated ...
Russell, S., Keegan, A., Harada, N., Nakamura, Y., Noguchi, M., Leland, P., Friedmann, M., Miyajima, A., Puri, R., Paul, W., Et, A.-L.   +10 more
openaire   +3 more sources