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Giant Cell Arteritis Refractory to Interleukin‐6 and Interleukin‐17 Inhibition Treated With Upadacitinib [PDF]
ACR Open RheumatologyGiant cell arteritis (GCA) is a granulomatous vasculitis that can involve both cranial and extracranial vessels. Although interleukin‐6 (IL‐6) receptor blockade is an established therapy, treatment options for medically refractory disease remain limited.
Luke S. Vest +4 more
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IL17A and IL17RA gene polymorphisms in Fanconi anemia [PDF]
Brazilian Oral Research, 2023 Fanconi anemia is a rare autosomal recessive disease. In this disease, cytokine pathways can induce the bone marrow failure that is observed in individuals with Fanconi anemia.
Rafael Zancan MOBILE +6 more
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Applied Sciences, 2022 Background: Periodontitis (P) is a chronic inflammatory disease characterized by the destruction of periodontium support tissue generated by different immuno-inflammatory mechanisms, including the RANK/RANKL/OPG and the IL-23/IL-17 axis.
Ruth Rodríguez-Montaño +7 more
doaj +1 more source
Interleukin 17 in early invasive breast cancer
Frontiers in Oncology, 2023 IntroductionInterleukin 17 (IL-17) has a key role in inflammatory responses. Increased serum concentrations of IL-17 have been reported in patients with different types of cancer.
Marina Popović +9 more
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Interleukin-17 Cytokines and Receptors: Potential Amplifiers of Tendon Inflammation
Frontiers in Bioengineering and Biotechnology, 2021 Interleukin (IL)-17A, a pro-inflammatory cytokine that is linked to the pathology of several inflammatory diseases, has been shown to be upregulated in early human tendinopathy and to mediate inflammatory and tissue remodelling events.
Jolet Y. Mimpen +3 more
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Relationship between interleukin 17 & 6 in patients with varicocele compare with a control group [PDF]
Journal of Medical and Life Science, 2019 The spermatogenesis process is very complex and involves many processes that lead to giving normal sperm, these sperms are very important for Fertility in the male.
Hayder AL-Msaid, Waleed H., Hydar Khalfa
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Revista da Sociedade Brasileira de Medicina Tropical, 2021 A 39-year-old woman was diagnosed with relapsed multibacillary leprosy and refractory neuritis. Here, we describe an evident loss of therapeutic effectiveness after the third pulse of corticosteroids, which may be attributed to tachyphylaxis and the ...
Patrícia Shu Kurizky +6 more
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Dental Research Journal, 2020 Background: Regarding the prevalence and importance of periodontal disease and the potential of salivary biomarkers for the early diagnosis of these diseases, this study was conducted to compare salivary concentrations of Interleukin-17 (IL-17) and ...
Surena Vahabi +2 more
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Current concepts in the pathogenesis of spondyloarthritis
Indian Journal of Rheumatology, 2020 Pathogenesis of spondyloarthritis (SpA) is multifactorial and still not understood entirely. The role of genetics including human leukocyte antigen B27 has been investigated extensively, which along with genome-wide association studies has helped us ...
Nibha Jain, Arumugam Moorthy
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Interleukin-17 Contributes to Chikungunya Virus-Induced Disease
mBio, 2022 Alphaviral arthritides caused by mosquito-borne arboviruses such as chikungunya virus (CHIKV) can persist for months after the initial acute disease.
Xiang Liu +10 more
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