Results 31 to 40 of about 579,314 (305)
Frontiers in Endocrinology, 2021 ObjectiveOsteoporosis is a common metabolic bone disease mainly involving bone remodeling and blood vessels. The current study aimed to explore the suppressive role of interleukin (IL)-35 in nuclear factor kappa-B ligand receptor activator (RANKL) and ...
Hui Zhang +7 more
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Targeting interleukin-17 receptors
Oncotarget, 2015 During the last decade, increasing evidence suggests a strong association between chronic inflammation and cancer development among different types of cancer. The dysregulation of pro-inflammatory cytokines or their receptors is a common feature observed in many cancers [1]. Cancer cells take advantage of cytokine or cytokine receptor overexpression to
Wen-Hwa, Lee +2 more
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Crohn's disease: Th1, Th17 or both? The change of a paradigm: new immunological and genetic insights implicate Th17 cells in the pathogenesis of Crohn's disease [PDF]
, 2009 Traditionally, Crohn's disease has been associated with a Th1 cytokine profile, while Th2 cytokines are modulators of ulcerative colitis. This concept has been challenged by the description of tolerising regulatory T cells (Treg) and by proinflammatory ...
Brand, Stephan
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International Journal of Occupational Medicine and Environmental Health, 2020 Objectives Venom immunotherapy (VIT) is an effective treatment method and is addressed to patients with a history of an anaphylactic reaction to Hymenoptera stings. However, the immunological mechanisms of protection have not been explained yet.
Krzysztof Pałgan +3 more
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Journal of Investigative Surgery, 2021 Background Idiopathic Granulomatous Mastitis (IGM) is a benign chronic inflammatory breast disease that mimics breast cancer, and the etiopathogenesis has not yet been fully evaluated. Autoimmunity has received the most focus as a possible etiology.
Mehmet Saydam +8 more
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Interleukin-17: A Revisited Study [PDF]
International Journal of Immunopathology and Pharmacology, 2004 Cytokine is a term used for a large group of proteins that are produced by a variety of cells in the body and act to stimulate, or inhibit, the functions of the same cells that produce them or of other cell types. The IL-17 family members are different in expressions and proinflammatory responses.
HUANG SH +14 more
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Faecalibacterium prausnitziiinhibits interleukin-17 to ameliorate colorectal colitis in rats [PDF]
, 2014 © 2014 Zhang et al. Results: The culture supernatant of F. prausnitzii increased plasma anti-Th17 cytokines (IL-10 and IL-12) and suppressed IL-17 levels in both plasma and colonic mucosa, with ameliorated colonic colitis lesions.
Chen, H +7 more
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Airway neutrophils and interleukin-17 [PDF]
European Respiratory Journal, 2000 It is well known that exacerbations of obstructive airways disease such as asthma and chronic obstructive pulmonary disease are associated with an increased number of neutrophils in the airways. However, the mechanisms behind this phenomenon are poorly understood.
A, Lindén, H, Hoshino, M, Laan
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Interleukin-17 Expression in the Barrett’s Metaplasia-Dysplasia-Adenocarcinoma Sequence [PDF]
, 2012 Original Research ArticleIntroduction. This pilot study evaluated the expression of the proinflammatory cytokine IL-17 along the Barrett’s metaplasia-dysplasia-adenocarcinoma sequence by establishing the expression levels of IL-17 in columnar epithelium,
Bannister, Jim R. +4 more
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The parasitic helminth product ES-62 suppresses pathogenesis in collagen-induced arthritis by targeting the interleukin-17–producing cellular network at multiple sites [PDF]
, 2012 Among many survival strategies, parasitic worms secrete molecules to modulate host immune responses. One such product, ES-62, is protective in the collagen-induced arthritis (CIA) model of rheumatoid arthritis.
Al-Riyami +47 more
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