Results 31 to 40 of about 4,561,988 (255)

Correlation of Interleukin-17 and 23 Inflammatory Markers with Genetically Transmitted Spondyloarthritis Patients at a Tertiary Care Facility, South India [PDF]

, 2023
Human leukocyte antigens (HLA) are genetically derived proteins in the major histocompatibility complex. They help distinguish “self” and “non-self” antigens and are essential in interacting with the immune cells inside the body.
K.V. Leela, Sujith Ravi, Balamurali Venkatesan, Om Lokesh Muthamilan, T. Jayaprakash   +4 more
core   +1 more source

Serum interleukin-17 (IL-17) in chronic periodontitis patients

Padjadjaran Journal of Dentistry, 2017
Introduction: Explorations into the periodontal medicine relationship have discovered interleukin-17 (IL-17) cytokine as one of the pro-inflammatory mediators that play a crucial role in the initiation and progression of the chronic periodontal disease ...
Erry Mochamad Arief, Marina binti Mubin, Siti Lailatul Akmar Zainuddin, Nurul Asma Abdullah, Basaruddin Ahmad   +4 more
doaj   +1 more source

The Treatment with Interleukin 17 Inhibitors and Immune-Mediated Inflammatory Diseases

Current Issues in Molecular Biology, 2022
IL-17 inhibitors (IL-17i) are medicines used to treat dermatological and rheumatic diseases They belong to a class of medicines called biological disease-modifying anti-rheumatic drugs (bDMARDs).
Laura Țiburcă, Marius Bembea, Dana Carmen Zaha, Alexandru Daniel Jurca, Cosmin Mihai Vesa, Ioana Adela Rațiu, Claudia Maria Jurca   +6 more
doaj   +1 more source

Interleukin-22 predicts severity and death in advanced liver cirrhosis: a prospective cohort study [PDF]

, 2012
Background: Interleukin-22 (IL-22), recently identified as a crucial parameter of pathology in experimental liver damage, may determine survival in clinical end-stage liver disease.
Stefan Zeuzem, Herrmann, Eva, Oliver Waidmann, Kronenberger, Bernd, Friederike Brunner, Rudloff, Ina, Bernd Kronenberger, Waidmann, Oliver, Albrecht Piiper, Pfeilschifter, Josef (Prof. Dr.), Piiper, Albrecht, Heiko Mühl, Filmann, Natalie, Ina Rudloff, Malte Bachmann, Eva Herrmann, Josef Pfeilschifter, Lisa Kapper, Bachmann, Malte, Brunner, Friederike, Kapper, Lisa, Mühl, Heiko, Natalie Filmann, Zeuzem, Stefan   +23 more
core   +2 more sources

Cytokines (interleukin-9, IL-17, IL-22, IL-25 and IL-33) and asthma

Advanced Biomedical Research, 2014
Asthma is a reversible airway obstruction that is characterized by constriction of airway smooth muscle, hyper secretion of mucus, edema and airway hyper responsiveness (AHR), mucus secretion and thickening of the basement membrane underlying the airway ...
Rahim Farahani, Roya Sherkat, Mazdak Ganjalikhani Hakemi, Nahid Eskandari, Reza Yazdani   +4 more
doaj   +1 more source

Comparative Evaluation of Hemodiafiltration, Hemoperfusion, and Standard Hemodialysis on Efficacy, Inflammatory Control, Dialysis Adequacy, and Safety in End‐Stage Renal Disease: A Prospective Observational Study

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo, Weisi Dai, Jie Mao, Mei Ye, Xingshan Lu, Xiaocui Zhang   +5 more
wiley   +1 more source

Interleukin-17: Potential Target for Chronic Wounds [PDF]

, 2019
Chronic wounds exhibit persistent inflammation with markedly delayed healing. The significant burden of chronic wounds, which are often resistant to standard therapy, prompts further research on novel therapies.
Dahle, Sara E, R. Rivkah Isseroff, Bagood, Michelle D, Isseroff, R Rivkah, Sood, Apra, Apra Sood, Sara E. Dahle, Hadian, Yasmin, Yasmin Hadian, Michelle D. Bagood   +9 more
core   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Th1/Th17 cell induction and corresponding reduction in ATP consumption following vaccination with the novel Mycobacterium tuberculosis vaccine MVA85A. [PDF]

, 2011
Vaccination with Bacille Calmette-Guérin (BCG) has traditionally been used for protection against disease caused by the bacterium Mycobacterium tuberculosis (M.tb). The efficacy of BCG, especially against pulmonary tuberculosis (TB) is variable. The best
Minassian, Angela M, Pathan, Ansar A, Sander Clare R., Hill, Adrian, Helen A. Fletcher, Fletcher, Helen A, Natalie E R Beveridge, Hill, AVS, Minassian Angela M., Angela M Minassian, Fletcher, HA, Kristin L. Griffiths, Pathan Ansar A., Kristin L Griffiths, Hill, Adrian VS, Griffiths Kristin L., Sander, CR, Hill Adrian V. S., McShane Helen, Beveridge Natalie E. R., Pathan, AA, Minassian, AM, Clare R. Sander, Ansar A. Pathan, Hill, AV, Griffiths, KL, Beveridge, NER, Clare R Sander, Helen McShane, Ansar A Pathan, Beveridge, NE, Natalie E. R. Beveridge, Griffiths , Kristin Lisa, Griffiths, Kristin L, Sander, Clare R, Adrian V S Hill, Adrian V. S. Hill, Helen A Fletcher, Fletcher Helen A., Beveridge, Natalie ER, McShane, H, Fletcher, Helen, Angela M. Minassian, McShane, Helen   +43 more
core   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source