Results 1 to 10 of about 3,701,935 (349)
Roles of interleukin-17 in uveitis [PDF]
Indian Journal of Ophthalmology, 2016 Th17 cells, a CD4+ T-cell subset, produce interleukin (IL)-17, a pro-inflammatory cytokine that has been shown to be involved in several forms of infectious and noninfectious uveitis.
Marta Catarina Esteves Guedes +2 more
doaj +8 more sources
Bioscience, Biotechnology, and Biochemistry, 2023 ABSTRACT This research is based on a Systematic Evolution of Ligands by EXponential enrichment, also referred to as in vitro selection against the extracellular domain of human interleukin-17 receptor A (IL-17RA). Pull-down assay via quantitative polymerase chain reaction and chemiluminescence detection showed that the cloned RNA with ...
Arifur Rahman Munshi +10 more
openaire +3 more sources
Interleukin-17 in Antifungal Immunity [PDF]
Pathogens, 2019 The field of IL-17 biology has received much attention over the last decade owing to the pathogenic role of this cytokine in psoriasis and other autoinflammatory disorders and the successful implementation of IL-17-targeting therapies in patients ...
Florian Sparber +1 more
doaj +6 more sources
The role of interleukin-17 in inflammation-related cancers. [PDF]
Front ImmunolEmerging evidence indicates a correlation between inflammation and the development and progression of cancer. Among the various inflammatory signals, interleukin-17 (IL-17) family cytokines serve as a critical link between inflammation and cancer.
Zhang X +6 more
europepmc +2 more sources
Interleukin‐17 and ischaemic stroke [PDF]
Immunology, 2020 SummaryInterleukin‐17 (IL‐17) is a cytokine family that includes 6 members, IL‐17A through IL‐17F, most of them are reported to have pro‐inflammatory role. Through binding to their receptors (IL‐17Rs), IL‐17 activates the intracellular signalling pathways to play an important role in autoimmune diseases, including rheumatoid arthritis (RA) and multiple
Qiaohui Zhang +6 more
openaire +3 more sources
Giant Cell Arteritis Refractory to Interleukin‐6 and Interleukin‐17 Inhibition Treated With Upadacitinib [PDF]
ACR Open RheumatologyGiant cell arteritis (GCA) is a granulomatous vasculitis that can involve both cranial and extracranial vessels. Although interleukin‐6 (IL‐6) receptor blockade is an established therapy, treatment options for medically refractory disease remain limited.
Luke S. Vest +4 more
doaj +2 more sources
IL17A and IL17RA gene polymorphisms in Fanconi anemia [PDF]
Brazilian Oral Research, 2023 Fanconi anemia is a rare autosomal recessive disease. In this disease, cytokine pathways can induce the bone marrow failure that is observed in individuals with Fanconi anemia.
Rafael Zancan MOBILE +6 more
doaj +1 more source
Applied Sciences, 2022 Background: Periodontitis (P) is a chronic inflammatory disease characterized by the destruction of periodontium support tissue generated by different immuno-inflammatory mechanisms, including the RANK/RANKL/OPG and the IL-23/IL-17 axis.
Ruth Rodríguez-Montaño +7 more
doaj +1 more source
Interleukin 17 in early invasive breast cancer
Frontiers in Oncology, 2023 IntroductionInterleukin 17 (IL-17) has a key role in inflammatory responses. Increased serum concentrations of IL-17 have been reported in patients with different types of cancer.
Marina Popović +9 more
doaj +1 more source
Nature Neuroscience, 2023 Hypertension can lead to cognitive impairment. However, the underlying mechanisms are unclear. Here, the authors show that meningeal T cell-produced interleukin-17 activates border-associated macrophages, affecting neurovascular and cognitive functions ...
Monica M. Santisteban +12 more
semanticscholar +1 more source