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Roles of interleukin-17 in uveitis [PDF]
Indian Journal of Ophthalmology, 2016 Th17 cells, a CD4+ T-cell subset, produce interleukin (IL)-17, a pro-inflammatory cytokine that has been shown to be involved in several forms of infectious and noninfectious uveitis.
Marta Catarina Esteves Guedes +2 more
doaj +6 more sources
Interleukin-17 in Antifungal Immunity [PDF]
Pathogens, 2019 The field of IL-17 biology has received much attention over the last decade owing to the pathogenic role of this cytokine in psoriasis and other autoinflammatory disorders and the successful implementation of IL-17-targeting therapies in patients ...
Florian Sparber +1 more
doaj +6 more sources
Interleukin-17 Contributes to Chikungunya Virus-Induced Disease
mBio, 2022 Alphaviral arthritides caused by mosquito-borne arboviruses such as chikungunya virus (CHIKV) can persist for months after the initial acute disease.
Xiang Liu +10 more
doaj +2 more sources
Interleukin-17: A Social Cytokine [PDF]
Cell, 2020 Some children with autism spectrum disorder (ASD) show behavioral improvements when experiencing inflammation accompanied by fever; however, little is known about the mechanisms that underlie these beneficial effects. In a recent issue of Nature, Reed and colleagues demonstrate that the production of interleukin-17 (IL-17) during inflammation promotes ...
Hoogenraad, Casper C. +1 more
openaire +4 more sources
Giant Cell Arteritis Refractory to Interleukin‐6 and Interleukin‐17 Inhibition Treated With Upadacitinib [PDF]
ACR Open RheumatologyGiant cell arteritis (GCA) is a granulomatous vasculitis that can involve both cranial and extracranial vessels. Although interleukin‐6 (IL‐6) receptor blockade is an established therapy, treatment options for medically refractory disease remain limited.
Luke S. Vest +4 more
doaj +2 more sources
The Saudi Journal of Gastroenterology, 2018 Background/Aim: We studied the expression of interleukin-17 and interleukin-22 in the serum and the lower esophageal sphincter (LES) in healthy individuals and in patients diagnosed with achalasia (AC) to gain a better understanding of the ...
Zeyu Wang +4 more
doaj +2 more sources
Interleukin-17 and fat: Timing is everything
ImmunityInterleukin-17 plays a major role in controlling adipose tissue homeostasis. In a recent study published in Nature, Douglas et al. demonstrate that time-of-day-dependent expression of interleukin-17 by tissue-resident innate lymphocytes in the adipose tissue drives circadian regulation of adipose tissue homeostasis and function.
Matthew C. Sinton +3 more
openaire +3 more sources
IL17A and IL17RA gene polymorphisms in Fanconi anemia [PDF]
Brazilian Oral Research, 2023 Fanconi anemia is a rare autosomal recessive disease. In this disease, cytokine pathways can induce the bone marrow failure that is observed in individuals with Fanconi anemia.
Rafael Zancan MOBILE +6 more
doaj +1 more source
Applied Sciences, 2022 Background: Periodontitis (P) is a chronic inflammatory disease characterized by the destruction of periodontium support tissue generated by different immuno-inflammatory mechanisms, including the RANK/RANKL/OPG and the IL-23/IL-17 axis.
Ruth Rodríguez-Montaño +7 more
doaj +1 more source
Interleukin 17 in early invasive breast cancer
Frontiers in Oncology, 2023 IntroductionInterleukin 17 (IL-17) has a key role in inflammatory responses. Increased serum concentrations of IL-17 have been reported in patients with different types of cancer.
Marina Popović +9 more
doaj +1 more source